View in EDS HTML Full Text PDF Full Text

Magnetocaloric materials as switchable high contrast ratio MRI labels.

Saved in:
Bibliographic Details
Title: Magnetocaloric materials as switchable high contrast ratio MRI labels.
Authors: Barbic, Mladen1 (AUTHOR) barbicm@janelia.hhmi.org, Dodd, Stephen J.2 (AUTHOR), Morris, H. Douglas3 (AUTHOR), Dilley, Neil4 (AUTHOR), Marcheschi, Barbara5 (AUTHOR), Huston, Alan5 (AUTHOR), Harris, Tim D.1 (AUTHOR), Koretsky, Alan P.2 (AUTHOR)
Source: Magnetic Resonance in Medicine. Apr2019, Vol. 81 Issue 4, p2238-2246. 9p.
Abstract: Purpose: To develop switchable and tunable labels with high contrast ratio for MRI using magnetocaloric materials that have sharp first‐order magnetic phase transitions at physiological temperatures and typical MRI magnetic field strengths. Methods: A prototypical magnetocaloric material iron‐rhodium (FeRh) was prepared by melt mixing, high‐temperature annealing, and ice‐water quenching. Temperature‐ and magnetic field‐dependent magnetization measurements of wire‐cut FeRh samples were performed on a vibrating sample magnetometer. Temperature‐dependent MRI of FeRh samples was performed on a 4.7T MRI. Results: Temperature‐dependent MRI clearly demonstrated image contrast changes due to the sharp magnetic state transition of the FeRh samples in the MRI magnetic field (4.7T) and at a physiologically relevant temperature (~37°C). Conclusion: A magnetocaloric material, FeRh, was demonstrated to act as a high contrast ratio switchable MRI contrast agent due to its sharp first‐order magnetic phase transition in the DC magnetic field of MRI and at physiologically relevant temperatures. A wide range of magnetocaloric materials are available that can be tuned by materials science techniques to optimize their response under MRI‐appropriate conditions and be controllably switched in situ with temperature, magnetic field, or a combination of both. [ABSTRACT FROM AUTHOR]
Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: egs
DbLabel: Engineering Source
An: 134666154
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Magnetocaloric materials as switchable high contrast ratio MRI labels.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Barbic%2C+Mladen%22">Barbic, Mladen</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> barbicm@janelia.hhmi.org</i><br /><searchLink fieldCode="AR" term="%22Dodd%2C+Stephen+J%2E%22">Dodd, Stephen J.</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Morris%2C+H%2E+Douglas%22">Morris, H. Douglas</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Dilley%2C+Neil%22">Dilley, Neil</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Marcheschi%2C+Barbara%22">Marcheschi, Barbara</searchLink><relatesTo>5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Huston%2C+Alan%22">Huston, Alan</searchLink><relatesTo>5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Harris%2C+Tim+D%2E%22">Harris, Tim D.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Koretsky%2C+Alan+P%2E%22">Koretsky, Alan P.</searchLink><relatesTo>2</relatesTo> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Magnetic+Resonance+in+Medicine%22">Magnetic Resonance in Medicine</searchLink>. Apr2019, Vol. 81 Issue 4, p2238-2246. 9p.
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Purpose: To develop switchable and tunable labels with high contrast ratio for MRI using magnetocaloric materials that have sharp first‐order magnetic phase transitions at physiological temperatures and typical MRI magnetic field strengths. Methods: A prototypical magnetocaloric material iron‐rhodium (FeRh) was prepared by melt mixing, high‐temperature annealing, and ice‐water quenching. Temperature‐ and magnetic field‐dependent magnetization measurements of wire‐cut FeRh samples were performed on a vibrating sample magnetometer. Temperature‐dependent MRI of FeRh samples was performed on a 4.7T MRI. Results: Temperature‐dependent MRI clearly demonstrated image contrast changes due to the sharp magnetic state transition of the FeRh samples in the MRI magnetic field (4.7T) and at a physiologically relevant temperature (~37°C). Conclusion: A magnetocaloric material, FeRh, was demonstrated to act as a high contrast ratio switchable MRI contrast agent due to its sharp first‐order magnetic phase transition in the DC magnetic field of MRI and at physiologically relevant temperatures. A wide range of magnetocaloric materials are available that can be tuned by materials science techniques to optimize their response under MRI‐appropriate conditions and be controllably switched in situ with temperature, magnetic field, or a combination of both. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=134666154
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1002/mrm.27615
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 9
        StartPage: 2238
    Titles:
      – TitleFull: Magnetocaloric materials as switchable high contrast ratio MRI labels.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Barbic, Mladen
      – PersonEntity:
          Name:
            NameFull: Dodd, Stephen J.
      – PersonEntity:
          Name:
            NameFull: Morris, H. Douglas
      – PersonEntity:
          Name:
            NameFull: Dilley, Neil
      – PersonEntity:
          Name:
            NameFull: Marcheschi, Barbara
      – PersonEntity:
          Name:
            NameFull: Huston, Alan
      – PersonEntity:
          Name:
            NameFull: Harris, Tim D.
      – PersonEntity:
          Name:
            NameFull: Koretsky, Alan P.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 04
              Text: Apr2019
              Type: published
              Y: 2019
          Identifiers:
            – Type: issn-print
              Value: 07403194
          Numbering:
            – Type: volume
              Value: 81
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: Magnetic Resonance in Medicine
              Type: main
ResultId 1