A modified polyvinylchloride surface with antibacterial and antifouling functions.
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| Title: | A modified polyvinylchloride surface with antibacterial and antifouling functions. |
|---|---|
| Authors: | Almousa, Rashed1,2 (AUTHOR), Wen, Xin1 (AUTHOR), Na, Sungsoo1 (AUTHOR), Anderson, Gregory3 (AUTHOR), Xie, Dong1 (AUTHOR) dxie@iupui.edu |
| Source: | Polymers for Advanced Technologies. May2019, Vol. 30 Issue 5, p1216-1225. 10p. |
| Subjects: | Bacterial adhesion, Cell adhesion, Surface coatings, Polyvinyl chloride, Bacterial growth, Staphylococcus aureus |
| Abstract: | Surfaces with antibacterial and hydrophilic properties are very attractive to cardiovascular applications. The objective of this study was to synthesize and immobilize a novel antibacterial and hydrophilic polymer onto surface of polyvinylchloride via an effective and mild surface coating technique. The surface coated with a terpolymer constructed with N‐vinylpyrrolidone, 3,4‐dichloro‐5‐hydroxy‐2(5H)‐furanone derivative, and succinimide residue was evaluated with cell adhesion, bacterial adhesion, and bacterial viability. 3T3 mouse fibroblast cells and two bacteria species were used to evaluate surface adhesion and antibacterial activity. Results showed that the polymer‐modified polyvinylchloride surface exhibited not only significantly decreased 3T3 fibroblast cell adhesion with a 66% to 87% reduction but also significantly decreased bacterial adhesion with 69% to 87% and 52% to 74% reduction of Pseudomonas aeruginosa and Staphylococcus aureus attachment, respectively, as compared with original polyvinylchloride. Furthermore, the modified polyvinylchloride surfaces exhibited significant antibacterial functions by inhibiting bacterial growth (75%‐84% and 78–94% inhibition of P aeruginosa and S aureus, respectively, as compared to original polyvinylchloride) and killing bacteria. These results demonstrate that covalent polymer attachment conferred antifouling and antibacterial properties to the polyvinylchloride surface. [ABSTRACT FROM AUTHOR] |
| Copyright of Polymers for Advanced Technologies is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Header | DbId: egs DbLabel: Engineering Source An: 135668631 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A modified polyvinylchloride surface with antibacterial and antifouling functions. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Almousa%2C+Rashed%22">Almousa, Rashed</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wen%2C+Xin%22">Wen, Xin</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Na%2C+Sungsoo%22">Na, Sungsoo</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Anderson%2C+Gregory%22">Anderson, Gregory</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Xie%2C+Dong%22">Xie, Dong</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> dxie@iupui.edu</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Polymers+for+Advanced+Technologies%22">Polymers for Advanced Technologies</searchLink>. May2019, Vol. 30 Issue 5, p1216-1225. 10p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Bacterial+adhesion%22">Bacterial adhesion</searchLink><br /><searchLink fieldCode="DE" term="%22Cell+adhesion%22">Cell adhesion</searchLink><br /><searchLink fieldCode="DE" term="%22Surface+coatings%22">Surface coatings</searchLink><br /><searchLink fieldCode="DE" term="%22Polyvinyl+chloride%22">Polyvinyl chloride</searchLink><br /><searchLink fieldCode="DE" term="%22Bacterial+growth%22">Bacterial growth</searchLink><br /><searchLink fieldCode="DE" term="%22Staphylococcus+aureus%22">Staphylococcus aureus</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Surfaces with antibacterial and hydrophilic properties are very attractive to cardiovascular applications. The objective of this study was to synthesize and immobilize a novel antibacterial and hydrophilic polymer onto surface of polyvinylchloride via an effective and mild surface coating technique. The surface coated with a terpolymer constructed with N‐vinylpyrrolidone, 3,4‐dichloro‐5‐hydroxy‐2(5H)‐furanone derivative, and succinimide residue was evaluated with cell adhesion, bacterial adhesion, and bacterial viability. 3T3 mouse fibroblast cells and two bacteria species were used to evaluate surface adhesion and antibacterial activity. Results showed that the polymer‐modified polyvinylchloride surface exhibited not only significantly decreased 3T3 fibroblast cell adhesion with a 66% to 87% reduction but also significantly decreased bacterial adhesion with 69% to 87% and 52% to 74% reduction of Pseudomonas aeruginosa and Staphylococcus aureus attachment, respectively, as compared with original polyvinylchloride. Furthermore, the modified polyvinylchloride surfaces exhibited significant antibacterial functions by inhibiting bacterial growth (75%‐84% and 78–94% inhibition of P aeruginosa and S aureus, respectively, as compared to original polyvinylchloride) and killing bacteria. These results demonstrate that covalent polymer attachment conferred antifouling and antibacterial properties to the polyvinylchloride surface. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Polymers for Advanced Technologies is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/pat.4554 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 10 StartPage: 1216 Subjects: – SubjectFull: Bacterial adhesion Type: general – SubjectFull: Cell adhesion Type: general – SubjectFull: Surface coatings Type: general – SubjectFull: Polyvinyl chloride Type: general – SubjectFull: Bacterial growth Type: general – SubjectFull: Staphylococcus aureus Type: general Titles: – TitleFull: A modified polyvinylchloride surface with antibacterial and antifouling functions. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Almousa, Rashed – PersonEntity: Name: NameFull: Wen, Xin – PersonEntity: Name: NameFull: Na, Sungsoo – PersonEntity: Name: NameFull: Anderson, Gregory – PersonEntity: Name: NameFull: Xie, Dong IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: May2019 Type: published Y: 2019 Identifiers: – Type: issn-print Value: 10427147 Numbering: – Type: volume Value: 30 – Type: issue Value: 5 Titles: – TitleFull: Polymers for Advanced Technologies Type: main |
| ResultId | 1 |
