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Advances in biosensors for the detection of ochratoxin A: Bio-receptors, nanomaterials, and their applications.

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Title: Advances in biosensors for the detection of ochratoxin A: Bio-receptors, nanomaterials, and their applications.
Authors: Alhamoud, Yasmin1 (AUTHOR), Yang, Danting1,2 (AUTHOR) yangdanting@nbu.edu.cn, Fiati Kenston, Samuel Selorm1 (AUTHOR), Liu, Guozhen2 (AUTHOR), Liu, Linyang2 (AUTHOR), Zhou, Haibo3 (AUTHOR), Ahmed, Fatma1 (AUTHOR), Zhao, Jinshun1 (AUTHOR) zhaojinshun@nbu.edu.cn
Source: Biosensors & Bioelectronics. Sep2019, Vol. 141, pN.PAG-N.PAG. 1p.
Subjects: Ochratoxins, Nanostructured materials, Biosensors, Bioelectronics, Brain diseases, Liver diseases, Penicillium
Abstract: Ochratoxin A (OTA) is a class of mycotoxin mainly produced by the genera Aspergillus and Penicillium. OTA can cause various forms of kidney, liver and brain diseases in both humans and animals although trace amount of OTA is normally present in food. Therefore, development of fast and sensitive detection technique is essential for accurate diagnosis of OTA. Currently, the most commonly used detection methods are enzyme-linked immune sorbent assays (ELISA) and chromatographic techniques. These techniques are sensitive but time consuming, and require expensive equipment, highly trained operators, as well as extensive preparation steps. These drawbacks limit their wide application in OTA detection. On the contrary, biosensors hold a great potential for OTA detection at for both research and industry because they are less expensive, rapid, sensitive, specific, simple and portable. This paper aims to provide an extensive overview on biosensors for OTA detection by highlighting the main biosensing recognition elements for OTA, the most commonly used nanomaterials for fabricating the sensing interface, and their applications in different read-out types of biosensors. Current challenges and future perspectives are discussed as well. • Four types of bio-receptors (antibodies/nanobodies, peptides, aptamers/DNases, MIPs) are introduced. • Different nanomaterials (CNMs, MBs/MNPs, QDs, UCNPs, MOFs) are investigated and compared. • Applications of different read-out biosensors (Optical, EC, Mass-sensitivity, and SERS biosensors) are discussed. • Future perspectives for biosensors of OTA are proposed. [ABSTRACT FROM AUTHOR]
Copyright of Biosensors & Bioelectronics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
An: 138253750
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  Data: Advances in biosensors for the detection of ochratoxin A: Bio-receptors, nanomaterials, and their applications.
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  Data: <searchLink fieldCode="AR" term="%22Alhamoud%2C+Yasmin%22">Alhamoud, Yasmin</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yang%2C+Danting%22">Yang, Danting</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> yangdanting@nbu.edu.cn</i><br /><searchLink fieldCode="AR" term="%22Fiati+Kenston%2C+Samuel+Selorm%22">Fiati Kenston, Samuel Selorm</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liu%2C+Guozhen%22">Liu, Guozhen</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liu%2C+Linyang%22">Liu, Linyang</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhou%2C+Haibo%22">Zhou, Haibo</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ahmed%2C+Fatma%22">Ahmed, Fatma</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhao%2C+Jinshun%22">Zhao, Jinshun</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> zhaojinshun@nbu.edu.cn</i>
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  Data: <searchLink fieldCode="JN" term="%22Biosensors+%26+Bioelectronics%22">Biosensors & Bioelectronics</searchLink>. Sep2019, Vol. 141, pN.PAG-N.PAG. 1p.
– Name: Subject
  Label: Subjects
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  Data: <searchLink fieldCode="DE" term="%22Ochratoxins%22">Ochratoxins</searchLink><br /><searchLink fieldCode="DE" term="%22Nanostructured+materials%22">Nanostructured materials</searchLink><br /><searchLink fieldCode="DE" term="%22Biosensors%22">Biosensors</searchLink><br /><searchLink fieldCode="DE" term="%22Bioelectronics%22">Bioelectronics</searchLink><br /><searchLink fieldCode="DE" term="%22Brain+diseases%22">Brain diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Liver+diseases%22">Liver diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Penicillium%22">Penicillium</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Ochratoxin A (OTA) is a class of mycotoxin mainly produced by the genera Aspergillus and Penicillium. OTA can cause various forms of kidney, liver and brain diseases in both humans and animals although trace amount of OTA is normally present in food. Therefore, development of fast and sensitive detection technique is essential for accurate diagnosis of OTA. Currently, the most commonly used detection methods are enzyme-linked immune sorbent assays (ELISA) and chromatographic techniques. These techniques are sensitive but time consuming, and require expensive equipment, highly trained operators, as well as extensive preparation steps. These drawbacks limit their wide application in OTA detection. On the contrary, biosensors hold a great potential for OTA detection at for both research and industry because they are less expensive, rapid, sensitive, specific, simple and portable. This paper aims to provide an extensive overview on biosensors for OTA detection by highlighting the main biosensing recognition elements for OTA, the most commonly used nanomaterials for fabricating the sensing interface, and their applications in different read-out types of biosensors. Current challenges and future perspectives are discussed as well. • Four types of bio-receptors (antibodies/nanobodies, peptides, aptamers/DNases, MIPs) are introduced. • Different nanomaterials (CNMs, MBs/MNPs, QDs, UCNPs, MOFs) are investigated and compared. • Applications of different read-out biosensors (Optical, EC, Mass-sensitivity, and SERS biosensors) are discussed. • Future perspectives for biosensors of OTA are proposed. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Biosensors & Bioelectronics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.bios.2019.111418
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 1
        StartPage: N.PAG
    Subjects:
      – SubjectFull: Ochratoxins
        Type: general
      – SubjectFull: Nanostructured materials
        Type: general
      – SubjectFull: Biosensors
        Type: general
      – SubjectFull: Bioelectronics
        Type: general
      – SubjectFull: Brain diseases
        Type: general
      – SubjectFull: Liver diseases
        Type: general
      – SubjectFull: Penicillium
        Type: general
    Titles:
      – TitleFull: Advances in biosensors for the detection of ochratoxin A: Bio-receptors, nanomaterials, and their applications.
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            NameFull: Alhamoud, Yasmin
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            – D: 15
              M: 09
              Text: Sep2019
              Type: published
              Y: 2019
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