Asymmetric ruthenium tricarbonyl cyclopentadienone complexes; synthesis and application to asymmetric hydrogenation of ketones.
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| Title: | Asymmetric ruthenium tricarbonyl cyclopentadienone complexes; synthesis and application to asymmetric hydrogenation of ketones. |
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| Authors: | Del Grosso, Alessandro1 (AUTHOR), Clarkson, Guy J.1 (AUTHOR), Wills, Martin1 (AUTHOR) m.wills@warwick.ac.uk |
| Source: | Inorganica Chimica Acta. Oct2019, Vol. 496, pN.PAG-N.PAG. 1p. |
| Subjects: | Asymmetric synthesis, Ruthenium, Transfer hydrogenation, Hydrogenation, Ketones, Dialkylzinc |
| Abstract: | • Novel enantiomerically-pure ruthenium tricarbonyl cyclopentadienones are reported. • Complexes were prepared via the cyclisation of C2-symmetric dialkynes with Ru3(CO) 12. • The new catalysts are effective in the asymmetric hydrogenation of ketones. • The new catalysts are prepared via an operationally simple procedure. A series of enantiomerically-pure ruthenium tricarbonyl cyclopentadienone complexes were prepared via the cyclisation of C2-symmetric dialkynes with Ru 3 (CO) 12. Four complexes were characterised by X-ray crystallography and a hydride derivative of one of these was characterised. The complexes were tested in the asymmetric hydrogenation and transfer hydrogenation of acetophenone. Whilst the catalysts were active, acetophenone was reduced in low ee, however a reduction product of up to 46% ee could be obtained when a mild base (i Pr 2 NEt or pyridine) was added to the reaction. [ABSTRACT FROM AUTHOR] |
| Copyright of Inorganica Chimica Acta is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 138888770 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Asymmetric ruthenium tricarbonyl cyclopentadienone complexes; synthesis and application to asymmetric hydrogenation of ketones. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Del+Grosso%2C+Alessandro%22">Del Grosso, Alessandro</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Clarkson%2C+Guy+J%2E%22">Clarkson, Guy J.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wills%2C+Martin%22">Wills, Martin</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> m.wills@warwick.ac.uk</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Inorganica+Chimica+Acta%22">Inorganica Chimica Acta</searchLink>. Oct2019, Vol. 496, pN.PAG-N.PAG. 1p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Asymmetric+synthesis%22">Asymmetric synthesis</searchLink><br /><searchLink fieldCode="DE" term="%22Ruthenium%22">Ruthenium</searchLink><br /><searchLink fieldCode="DE" term="%22Transfer+hydrogenation%22">Transfer hydrogenation</searchLink><br /><searchLink fieldCode="DE" term="%22Hydrogenation%22">Hydrogenation</searchLink><br /><searchLink fieldCode="DE" term="%22Ketones%22">Ketones</searchLink><br /><searchLink fieldCode="DE" term="%22Dialkylzinc%22">Dialkylzinc</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: • Novel enantiomerically-pure ruthenium tricarbonyl cyclopentadienones are reported. • Complexes were prepared via the cyclisation of C2-symmetric dialkynes with Ru3(CO) 12. • The new catalysts are effective in the asymmetric hydrogenation of ketones. • The new catalysts are prepared via an operationally simple procedure. A series of enantiomerically-pure ruthenium tricarbonyl cyclopentadienone complexes were prepared via the cyclisation of C2-symmetric dialkynes with Ru 3 (CO) 12. Four complexes were characterised by X-ray crystallography and a hydride derivative of one of these was characterised. The complexes were tested in the asymmetric hydrogenation and transfer hydrogenation of acetophenone. Whilst the catalysts were active, acetophenone was reduced in low ee, however a reduction product of up to 46% ee could be obtained when a mild base (i Pr 2 NEt or pyridine) was added to the reaction. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Inorganica Chimica Acta is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ica.2019.119043 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 1 StartPage: N.PAG Subjects: – SubjectFull: Asymmetric synthesis Type: general – SubjectFull: Ruthenium Type: general – SubjectFull: Transfer hydrogenation Type: general – SubjectFull: Hydrogenation Type: general – SubjectFull: Ketones Type: general – SubjectFull: Dialkylzinc Type: general Titles: – TitleFull: Asymmetric ruthenium tricarbonyl cyclopentadienone complexes; synthesis and application to asymmetric hydrogenation of ketones. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Del Grosso, Alessandro – PersonEntity: Name: NameFull: Clarkson, Guy J. – PersonEntity: Name: NameFull: Wills, Martin IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: Oct2019 Type: published Y: 2019 Identifiers: – Type: issn-print Value: 00201693 Numbering: – Type: volume Value: 496 Titles: – TitleFull: Inorganica Chimica Acta Type: main |
| ResultId | 1 |
