Broadband lung dielectric properties over the ablative temperature range: Experimental measurements and parametric models.
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| Title: | Broadband lung dielectric properties over the ablative temperature range: Experimental measurements and parametric models. |
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| Authors: | Sebek, Jan1,2 (AUTHOR), Bortel, Radoslav2 (AUTHOR), Prakash, Punit1 (AUTHOR) prakashp@ksu.edu |
| Source: | Medical Physics. Oct2019, Vol. 46 Issue 10, p4291-4303. 13p. |
| Subjects: | Dielectric properties, Parametric modeling, Permittivity, Standard deviations, Lungs |
| Abstract: | Purpose: Computational models of microwave tissue ablation are widely used to guide the development of ablation devices, and are increasingly being used for the development of treatment planning and monitoring platforms. Knowledge of temperature‐dependent dielectric properties of lung tissue is essential for accurate modeling of microwave ablation (MWA) of the lung. Methods: We employed the open‐ended coaxial probe method, coupled with a custom tissue heating apparatus, to measure dielectric properties of ex vivo porcine and bovine lung tissue at temperatures ranging between 31 and 150 ∘C, over the frequency range 500 MHz to 6 GHz. Furthermore, we employed numerical optimization techniques to provide parametric models for characterizing the broadband temperature‐dependent dielectric properties of tissue, and their variability across tissue samples, suitable for use in computational models of microwave tissue ablation. Results: Rapid decreases in both relative permittivity and effective conductivity were observed in the temperature range from 94 to 108 ∘C. Over the measured frequency range, both relative permittivity and effective conductivity were suitably modeled by piecewise linear functions [root mean square error (RMSE) = 1.0952 for permittivity and 0.0650 S/m for conductivity]. Detailed characterization of the variability in lung tissue properties was provided to enable uncertainty quantification of models of MWA. Conclusions: The reported dielectric properties of lung tissue, and parametric models which also capture their distribution, will aid the development of computational models of microwave lung ablation. [ABSTRACT FROM AUTHOR] |
| Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Header | DbId: egs DbLabel: Engineering Source An: 139190154 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Broadband lung dielectric properties over the ablative temperature range: Experimental measurements and parametric models. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Sebek%2C+Jan%22">Sebek, Jan</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bortel%2C+Radoslav%22">Bortel, Radoslav</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Prakash%2C+Punit%22">Prakash, Punit</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> prakashp@ksu.edu</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Medical+Physics%22">Medical Physics</searchLink>. Oct2019, Vol. 46 Issue 10, p4291-4303. 13p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Dielectric+properties%22">Dielectric properties</searchLink><br /><searchLink fieldCode="DE" term="%22Parametric+modeling%22">Parametric modeling</searchLink><br /><searchLink fieldCode="DE" term="%22Permittivity%22">Permittivity</searchLink><br /><searchLink fieldCode="DE" term="%22Standard+deviations%22">Standard deviations</searchLink><br /><searchLink fieldCode="DE" term="%22Lungs%22">Lungs</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Purpose: Computational models of microwave tissue ablation are widely used to guide the development of ablation devices, and are increasingly being used for the development of treatment planning and monitoring platforms. Knowledge of temperature‐dependent dielectric properties of lung tissue is essential for accurate modeling of microwave ablation (MWA) of the lung. Methods: We employed the open‐ended coaxial probe method, coupled with a custom tissue heating apparatus, to measure dielectric properties of ex vivo porcine and bovine lung tissue at temperatures ranging between 31 and 150 ∘C, over the frequency range 500 MHz to 6 GHz. Furthermore, we employed numerical optimization techniques to provide parametric models for characterizing the broadband temperature‐dependent dielectric properties of tissue, and their variability across tissue samples, suitable for use in computational models of microwave tissue ablation. Results: Rapid decreases in both relative permittivity and effective conductivity were observed in the temperature range from 94 to 108 ∘C. Over the measured frequency range, both relative permittivity and effective conductivity were suitably modeled by piecewise linear functions [root mean square error (RMSE) = 1.0952 for permittivity and 0.0650 S/m for conductivity]. Detailed characterization of the variability in lung tissue properties was provided to enable uncertainty quantification of models of MWA. Conclusions: The reported dielectric properties of lung tissue, and parametric models which also capture their distribution, will aid the development of computational models of microwave lung ablation. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=139190154 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/mp.13704 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 13 StartPage: 4291 Subjects: – SubjectFull: Dielectric properties Type: general – SubjectFull: Parametric modeling Type: general – SubjectFull: Permittivity Type: general – SubjectFull: Standard deviations Type: general – SubjectFull: Lungs Type: general Titles: – TitleFull: Broadband lung dielectric properties over the ablative temperature range: Experimental measurements and parametric models. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sebek, Jan – PersonEntity: Name: NameFull: Bortel, Radoslav – PersonEntity: Name: NameFull: Prakash, Punit IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: Oct2019 Type: published Y: 2019 Identifiers: – Type: issn-print Value: 00942405 Numbering: – Type: volume Value: 46 – Type: issue Value: 10 Titles: – TitleFull: Medical Physics Type: main |
| ResultId | 1 |
