Layer by Layer Antimicrobial Coatings Based on Nafion, Lysozyme, and Chitosan.

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Title: Layer by Layer Antimicrobial Coatings Based on Nafion, Lysozyme, and Chitosan.
Authors: Gibbons, Ella N.1 (AUTHOR), Winder, Charis2 (AUTHOR), Barron, Elliot2 (AUTHOR), Fernandes, Diogo3 (AUTHOR), Krysmann, Marta J.1 (AUTHOR) mkrysmann@uclan.ac.uk, Kelarakis, Antonios2 (AUTHOR) mkrysmann@uclan.ac.uk, Parry, Adam V. S.4 (AUTHOR), Yeates, Stephen G.4 (AUTHOR)
Source: Nanomaterials (2079-4991). Nov2019, Vol. 9 Issue 11, p1563-1563. 1p.
Subjects: Lysozymes, Nafion, Quartz crystal microbalances, Chitosan, Atomic force microscopy, Contact angle
Abstract: The study focuses on the development of a new family of layer-by-layer coatings comprising Nafion, lysozyme and chitosan to address challenges related to microbial contamination. Circular dichroism was employed to gain insights on the interactions of the building blocks at the molecular level. Quartz crystal microbalance tests were used to monitor in real time the build-up of multilayer coatings, while atomic force microscopy, contact angle and surface zeta potential measurements were performed to assess the surface characteristics of the multilayer assemblies. Remarkably, the nanocoated surfaces show almost 100% reduction in the population of both Escherichia coli and Staphylococcus aureus. The study suggests that Nafion based synergistic platforms can offer an effective line of defence against bacteria, facilitating antimicrobial mechanisms that go beyond the concept of exclusion zone. [ABSTRACT FROM AUTHOR]
Copyright of Nanomaterials (2079-4991) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Layer by Layer Antimicrobial Coatings Based on Nafion, Lysozyme, and Chitosan.
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  Data: <searchLink fieldCode="JN" term="%22Nanomaterials+%282079-4991%29%22">Nanomaterials (2079-4991)</searchLink>. Nov2019, Vol. 9 Issue 11, p1563-1563. 1p.
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  Data: <searchLink fieldCode="DE" term="%22Lysozymes%22">Lysozymes</searchLink><br /><searchLink fieldCode="DE" term="%22Nafion%22">Nafion</searchLink><br /><searchLink fieldCode="DE" term="%22Quartz+crystal+microbalances%22">Quartz crystal microbalances</searchLink><br /><searchLink fieldCode="DE" term="%22Chitosan%22">Chitosan</searchLink><br /><searchLink fieldCode="DE" term="%22Atomic+force+microscopy%22">Atomic force microscopy</searchLink><br /><searchLink fieldCode="DE" term="%22Contact+angle%22">Contact angle</searchLink>
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  Data: The study focuses on the development of a new family of layer-by-layer coatings comprising Nafion, lysozyme and chitosan to address challenges related to microbial contamination. Circular dichroism was employed to gain insights on the interactions of the building blocks at the molecular level. Quartz crystal microbalance tests were used to monitor in real time the build-up of multilayer coatings, while atomic force microscopy, contact angle and surface zeta potential measurements were performed to assess the surface characteristics of the multilayer assemblies. Remarkably, the nanocoated surfaces show almost 100% reduction in the population of both Escherichia coli and Staphylococcus aureus. The study suggests that Nafion based synergistic platforms can offer an effective line of defence against bacteria, facilitating antimicrobial mechanisms that go beyond the concept of exclusion zone. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Nanomaterials (2079-4991) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – SubjectFull: Quartz crystal microbalances
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      – SubjectFull: Chitosan
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      – SubjectFull: Contact angle
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      – TitleFull: Layer by Layer Antimicrobial Coatings Based on Nafion, Lysozyme, and Chitosan.
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              Text: Nov2019
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