Biophysical Characterization of (Silica-coated) Cobalt Ferrite Nanoparticles for Hyperthermia Treatment.
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| Title: | Biophysical Characterization of (Silica-coated) Cobalt Ferrite Nanoparticles for Hyperthermia Treatment. |
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| Authors: | Lucht, Niklas1 (AUTHOR), Friedrich, Ralf P.2 (AUTHOR), Draack, Sebastian3 (AUTHOR), Alexiou, Christoph2 (AUTHOR), Viereck, Thilo3 (AUTHOR), Ludwig, Frank3 (AUTHOR), Hankiewicz, Birgit1 (AUTHOR) birgit.hankiewicz@chemie.uni-hamburg.de |
| Source: | Nanomaterials (2079-4991). Dec2019, Vol. 9 Issue 12, p1713-1713. 1p. |
| Subjects: | Heat stroke, Ferrites, Cobalt, Copper ferrite, Nickel ferrite, Nanoparticles |
| Abstract: | Magnetic hyperthermia is a technique that describes the heating of material through an external magnetic field. Classic hyperthermia is a medical condition where the human body overheats, being usually triggered by a heat stroke, which can lead to severe damage to organs and tissue due to the denaturation of cells. In modern medicine, hyperthermia can be deliberately induced to specified parts of the body to destroy malignant cells. Magnetic hyperthermia describes the way that this overheating is induced and it has the inherent advantage of being a minimal invasive method when compared to traditional surgery methods. This work presents a particle system that offers huge potential for hyperthermia treatments, given its good loss value, i.e., the particles dissipate a lot of heat to their surroundings when treated with an ac magnetic field. The measurements were performed in a low-cost custom hyperthermia setup. Additional toxicity assessments on Jurkat cells show a very low short-term toxicity on the particles and a moderate low toxicity after two days due to the prevalent health concerns towards nanoparticles in organisms. [ABSTRACT FROM AUTHOR] |
| Copyright of Nanomaterials (2079-4991) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Header | DbId: egs DbLabel: Engineering Source An: 140941595 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Biophysical Characterization of (Silica-coated) Cobalt Ferrite Nanoparticles for Hyperthermia Treatment. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Lucht%2C+Niklas%22">Lucht, Niklas</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Friedrich%2C+Ralf+P%2E%22">Friedrich, Ralf P.</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Draack%2C+Sebastian%22">Draack, Sebastian</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Alexiou%2C+Christoph%22">Alexiou, Christoph</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Viereck%2C+Thilo%22">Viereck, Thilo</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ludwig%2C+Frank%22">Ludwig, Frank</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hankiewicz%2C+Birgit%22">Hankiewicz, Birgit</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> birgit.hankiewicz@chemie.uni-hamburg.de</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Nanomaterials+%282079-4991%29%22">Nanomaterials (2079-4991)</searchLink>. Dec2019, Vol. 9 Issue 12, p1713-1713. 1p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Heat+stroke%22">Heat stroke</searchLink><br /><searchLink fieldCode="DE" term="%22Ferrites%22">Ferrites</searchLink><br /><searchLink fieldCode="DE" term="%22Cobalt%22">Cobalt</searchLink><br /><searchLink fieldCode="DE" term="%22Copper+ferrite%22">Copper ferrite</searchLink><br /><searchLink fieldCode="DE" term="%22Nickel+ferrite%22">Nickel ferrite</searchLink><br /><searchLink fieldCode="DE" term="%22Nanoparticles%22">Nanoparticles</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Magnetic hyperthermia is a technique that describes the heating of material through an external magnetic field. Classic hyperthermia is a medical condition where the human body overheats, being usually triggered by a heat stroke, which can lead to severe damage to organs and tissue due to the denaturation of cells. In modern medicine, hyperthermia can be deliberately induced to specified parts of the body to destroy malignant cells. Magnetic hyperthermia describes the way that this overheating is induced and it has the inherent advantage of being a minimal invasive method when compared to traditional surgery methods. This work presents a particle system that offers huge potential for hyperthermia treatments, given its good loss value, i.e., the particles dissipate a lot of heat to their surroundings when treated with an ac magnetic field. The measurements were performed in a low-cost custom hyperthermia setup. Additional toxicity assessments on Jurkat cells show a very low short-term toxicity on the particles and a moderate low toxicity after two days due to the prevalent health concerns towards nanoparticles in organisms. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Nanomaterials (2079-4991) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3390/nano9121713 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 1 StartPage: 1713 Subjects: – SubjectFull: Heat stroke Type: general – SubjectFull: Ferrites Type: general – SubjectFull: Cobalt Type: general – SubjectFull: Copper ferrite Type: general – SubjectFull: Nickel ferrite Type: general – SubjectFull: Nanoparticles Type: general Titles: – TitleFull: Biophysical Characterization of (Silica-coated) Cobalt Ferrite Nanoparticles for Hyperthermia Treatment. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lucht, Niklas – PersonEntity: Name: NameFull: Friedrich, Ralf P. – PersonEntity: Name: NameFull: Draack, Sebastian – PersonEntity: Name: NameFull: Alexiou, Christoph – PersonEntity: Name: NameFull: Viereck, Thilo – PersonEntity: Name: NameFull: Ludwig, Frank – PersonEntity: Name: NameFull: Hankiewicz, Birgit IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: Dec2019 Type: published Y: 2019 Identifiers: – Type: issn-print Value: 20794991 Numbering: – Type: volume Value: 9 – Type: issue Value: 12 Titles: – TitleFull: Nanomaterials (2079-4991) Type: main |
| ResultId | 1 |
