Comprehensive two-dimensional gas chromatography thermodynamic modeling and selectivity evaluation for the separation of polychlorinated dibenzo-p-dioxins and dibenzofurans in fish tissue matrix.
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| Title: | Comprehensive two-dimensional gas chromatography thermodynamic modeling and selectivity evaluation for the separation of polychlorinated dibenzo-p-dioxins and dibenzofurans in fish tissue matrix. |
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| Authors: | Stultz, Conner1 (AUTHOR), Jaramillo, Roman1 (AUTHOR), Teehan, Paige2 (AUTHOR), Dorman, Frank1,2 (AUTHOR) fld3@psu.edu |
| Source: | Journal of Chromatography A. Aug2020, Vol. 1626, pN.PAG-N.PAG. 1p. |
| Subjects: | Polychlorinated dibenzofurans, Gas chromatography, Capillary columns, Dioxins, Pattern matching |
| Abstract: | • Rxi-17SilMS crossed with Rtx-Dioxin2 can be used for dioxin analysis in GC×GC. • All 17 toxic dioxins are separated from each other in a single separation. • 11 toxic dioxins are fully resolved from interfering dioxin congeners. • Successful GC×GC modeling of 40 dioxin congeners. Comprehensive two-dimensional gas chromatography (GC×GC) is a powerful tool for complex separations. The selectivity and sensitivity benefits from thermally modulated GC×GC were applied to the analysis of polychlorinated dibenzo- p -dioxins and dibenzofurans (PCDD/Fs). Thermodynamic indices of 50 PCDD/Fs, including the 17 toxic 2378-substituted congeners, were collected and used to model one-dimensional and two-dimensional separations with the Rtx-Dioxin2 and Rxi-17SilMS capillary GC columns. Thermodynamic modeling was used to determine the optimal conditions to take advantage of the selectivity differences between the Rxi-17SilMS and Rtx-Dioxin2 to separate all PCDD/Fs congeners from the 2378-substituted compounds by GC×GC. The modeled elution order patterns closely matched the experimental elution order in 40 of the 45 tetrachlorinated through hexchlorinated compounds analyzed. The heptachlorinated and octachlorinated congeners were not included in the elution order modeling as they are readily resolved from other dioxin congeners. The Rxi-17SilMS crossed with the Rtx-Dioxin2 was able to separate all 2378-substituted compounds in a single separation in a fish matrix. Thirty-three additional PCDD/F congeners were added to the fish matrix that coelute with the 2378-substituted congeners. The Rxi-17SilMS crossed with the Rtx-Dioxin2 was able to fully resolve 11 of the 2378-substituted congeners with the other six congeners exhibiting coelutions with only one other congener. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Chromatography A is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 145068402 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Comprehensive two-dimensional gas chromatography thermodynamic modeling and selectivity evaluation for the separation of polychlorinated dibenzo-p-dioxins and dibenzofurans in fish tissue matrix. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Stultz%2C+Conner%22">Stultz, Conner</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Jaramillo%2C+Roman%22">Jaramillo, Roman</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Teehan%2C+Paige%22">Teehan, Paige</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Dorman%2C+Frank%22">Dorman, Frank</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> fld3@psu.edu</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Chromatography+A%22">Journal of Chromatography A</searchLink>. Aug2020, Vol. 1626, pN.PAG-N.PAG. 1p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Polychlorinated+dibenzofurans%22">Polychlorinated dibenzofurans</searchLink><br /><searchLink fieldCode="DE" term="%22Gas+chromatography%22">Gas chromatography</searchLink><br /><searchLink fieldCode="DE" term="%22Capillary+columns%22">Capillary columns</searchLink><br /><searchLink fieldCode="DE" term="%22Dioxins%22">Dioxins</searchLink><br /><searchLink fieldCode="DE" term="%22Pattern+matching%22">Pattern matching</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: • Rxi-17SilMS crossed with Rtx-Dioxin2 can be used for dioxin analysis in GC×GC. • All 17 toxic dioxins are separated from each other in a single separation. • 11 toxic dioxins are fully resolved from interfering dioxin congeners. • Successful GC×GC modeling of 40 dioxin congeners. Comprehensive two-dimensional gas chromatography (GC×GC) is a powerful tool for complex separations. The selectivity and sensitivity benefits from thermally modulated GC×GC were applied to the analysis of polychlorinated dibenzo- p -dioxins and dibenzofurans (PCDD/Fs). Thermodynamic indices of 50 PCDD/Fs, including the 17 toxic 2378-substituted congeners, were collected and used to model one-dimensional and two-dimensional separations with the Rtx-Dioxin2 and Rxi-17SilMS capillary GC columns. Thermodynamic modeling was used to determine the optimal conditions to take advantage of the selectivity differences between the Rxi-17SilMS and Rtx-Dioxin2 to separate all PCDD/Fs congeners from the 2378-substituted compounds by GC×GC. The modeled elution order patterns closely matched the experimental elution order in 40 of the 45 tetrachlorinated through hexchlorinated compounds analyzed. The heptachlorinated and octachlorinated congeners were not included in the elution order modeling as they are readily resolved from other dioxin congeners. The Rxi-17SilMS crossed with the Rtx-Dioxin2 was able to separate all 2378-substituted compounds in a single separation in a fish matrix. Thirty-three additional PCDD/F congeners were added to the fish matrix that coelute with the 2378-substituted congeners. The Rxi-17SilMS crossed with the Rtx-Dioxin2 was able to fully resolve 11 of the 2378-substituted congeners with the other six congeners exhibiting coelutions with only one other congener. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Chromatography A is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.chroma.2020.461311 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 1 StartPage: N.PAG Subjects: – SubjectFull: Polychlorinated dibenzofurans Type: general – SubjectFull: Gas chromatography Type: general – SubjectFull: Capillary columns Type: general – SubjectFull: Dioxins Type: general – SubjectFull: Pattern matching Type: general Titles: – TitleFull: Comprehensive two-dimensional gas chromatography thermodynamic modeling and selectivity evaluation for the separation of polychlorinated dibenzo-p-dioxins and dibenzofurans in fish tissue matrix. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Stultz, Conner – PersonEntity: Name: NameFull: Jaramillo, Roman – PersonEntity: Name: NameFull: Teehan, Paige – PersonEntity: Name: NameFull: Dorman, Frank IsPartOfRelationships: – BibEntity: Dates: – D: 30 M: 08 Text: Aug2020 Type: published Y: 2020 Identifiers: – Type: issn-print Value: 00219673 Numbering: – Type: volume Value: 1626 Titles: – TitleFull: Journal of Chromatography A Type: main |
| ResultId | 1 |
