Vessel-selective 4D-MR angiography using super-selective pseudo-continuous arterial spin labeling may be a useful tool for assessing brain AVM hemodynamics.
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| Title: | Vessel-selective 4D-MR angiography using super-selective pseudo-continuous arterial spin labeling may be a useful tool for assessing brain AVM hemodynamics. |
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| Authors: | Togao, Osamu1 (AUTHOR), Obara, Makoto2 (AUTHOR), Helle, Michael3 (AUTHOR), Yamashita, Koji1 (AUTHOR), Kikuchi, Kazufumi1 (AUTHOR), Momosaka, Daichi1 (AUTHOR), Kikuchi, Yoshitomo1 (AUTHOR), Nishimura, Ataru4 (AUTHOR), Arimura, Koichi4 (AUTHOR), Wada, Tatsuhiro5 (AUTHOR), Murazaki, Hiroo5 (AUTHOR), Iihara, Koji4 (AUTHOR), Van Cauteren, Marc2 (AUTHOR), Hiwatashi, Akio6 (AUTHOR) hiwatasi@radiol.med.kyushu-u.ac.jp |
| Source: | European Radiology. Dec2020, Vol. 30 Issue 12, p6452-6463. 12p. 3 Black and White Photographs, 1 Diagram, 4 Charts, 1 Graph. |
| Subjects: | Spin labels, Digital subtraction angiography, Cerebral arteriovenous malformations, Angiography, Magnetic resonance angiography |
| Abstract: | Objectives: To evaluate the usefulness of 4D-MR angiography based on super-selective pseudo-continuous ASL combined with keyhole and view-sharing (4D-S-PACK) for vessel-selective visualization and to examine the ability of this technique to visualize brain arteriovenous malformations (AVMs). Methods: In this retrospective study, 15 patients (ten men and five women, mean age 44.0 ± 16.9 years) with brain AVMs were enrolled. All patients were imaged with 4D-PACK (non-selective), 4D-S-PACK, and digital subtraction angiography (DSA). Observers evaluated vessel selectivity, identification of feeding arteries and venous drainage patterns, visualization scores, and contrast-to-noise ratio (CNR) for each AVM component. Measurements were compared between the MR methods. Results: Vessel selectivity was graded 4 in 43/45 (95.6%, observer 1) and 42/45 (93.3%, observer 2) territories and graded 3 in two (observer 1) and three (observer 2) territories. The sensitivity and specificity for identification of feeding arteries for both observers was 88.9% and 100% on 4D-PACK, and 100% and 100% on 4D-S-PACK, respectively. For venous drainage, the sensitivity and specificity was 100% on both methods for observer 1. The sensitivity and specificity for observer 2 was 94.4% and 83.3% on 4D-PACK, and 94.4% and 91.7% on 4D-S-PACK, respectively. The CNRs at the timepoint of 1600 ms were slightly lower in 4D-S-PACK than in 4D-PACK for all AVM components (Feeding artery, p =.02; nidus, p =.001; and draining artery, p =.02). The visualization scores for both observers were not significantly different between 4D-PACK and 4D-S-PACK for all components. Conclusions: 4D-S-PACK could be a useful non-invasive clinical tool for assessing hemodynamics in brain AVMs. Key Points: • The 4D-MR angiography based on super-selective pseudo-continuous arterial spin labeling combined with CENTRA-keyhole and view-sharing (4D-S-PACK) enabled excellent vessel selectivity. • The 4D-S-PACK enabled the perfect identification of feeding arteries of brain arteriovenous malformation (AVM). • 4D-S-PACK could be a non-invasive clinical tool for assessing hemodynamics in brain AVMs. [ABSTRACT FROM AUTHOR] |
| Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
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| Items | – Name: Title Label: Title Group: Ti Data: Vessel-selective 4D-MR angiography using super-selective pseudo-continuous arterial spin labeling may be a useful tool for assessing brain AVM hemodynamics. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Togao%2C+Osamu%22">Togao, Osamu</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Obara%2C+Makoto%22">Obara, Makoto</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Helle%2C+Michael%22">Helle, Michael</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yamashita%2C+Koji%22">Yamashita, Koji</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kikuchi%2C+Kazufumi%22">Kikuchi, Kazufumi</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Momosaka%2C+Daichi%22">Momosaka, Daichi</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kikuchi%2C+Yoshitomo%22">Kikuchi, Yoshitomo</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nishimura%2C+Ataru%22">Nishimura, Ataru</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Arimura%2C+Koichi%22">Arimura, Koichi</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wada%2C+Tatsuhiro%22">Wada, Tatsuhiro</searchLink><relatesTo>5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Murazaki%2C+Hiroo%22">Murazaki, Hiroo</searchLink><relatesTo>5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Iihara%2C+Koji%22">Iihara, Koji</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Van+Cauteren%2C+Marc%22">Van Cauteren, Marc</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hiwatashi%2C+Akio%22">Hiwatashi, Akio</searchLink><relatesTo>6</relatesTo> (AUTHOR)<i> hiwatasi@radiol.med.kyushu-u.ac.jp</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22European+Radiology%22">European Radiology</searchLink>. Dec2020, Vol. 30 Issue 12, p6452-6463. 12p. 3 Black and White Photographs, 1 Diagram, 4 Charts, 1 Graph. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Spin+labels%22">Spin labels</searchLink><br /><searchLink fieldCode="DE" term="%22Digital+subtraction+angiography%22">Digital subtraction angiography</searchLink><br /><searchLink fieldCode="DE" term="%22Cerebral+arteriovenous+malformations%22">Cerebral arteriovenous malformations</searchLink><br /><searchLink fieldCode="DE" term="%22Angiography%22">Angiography</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetic+resonance+angiography%22">Magnetic resonance angiography</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Objectives: To evaluate the usefulness of 4D-MR angiography based on super-selective pseudo-continuous ASL combined with keyhole and view-sharing (4D-S-PACK) for vessel-selective visualization and to examine the ability of this technique to visualize brain arteriovenous malformations (AVMs). Methods: In this retrospective study, 15 patients (ten men and five women, mean age 44.0 ± 16.9 years) with brain AVMs were enrolled. All patients were imaged with 4D-PACK (non-selective), 4D-S-PACK, and digital subtraction angiography (DSA). Observers evaluated vessel selectivity, identification of feeding arteries and venous drainage patterns, visualization scores, and contrast-to-noise ratio (CNR) for each AVM component. Measurements were compared between the MR methods. Results: Vessel selectivity was graded 4 in 43/45 (95.6%, observer 1) and 42/45 (93.3%, observer 2) territories and graded 3 in two (observer 1) and three (observer 2) territories. The sensitivity and specificity for identification of feeding arteries for both observers was 88.9% and 100% on 4D-PACK, and 100% and 100% on 4D-S-PACK, respectively. For venous drainage, the sensitivity and specificity was 100% on both methods for observer 1. The sensitivity and specificity for observer 2 was 94.4% and 83.3% on 4D-PACK, and 94.4% and 91.7% on 4D-S-PACK, respectively. The CNRs at the timepoint of 1600 ms were slightly lower in 4D-S-PACK than in 4D-PACK for all AVM components (Feeding artery, p =.02; nidus, p =.001; and draining artery, p =.02). The visualization scores for both observers were not significantly different between 4D-PACK and 4D-S-PACK for all components. Conclusions: 4D-S-PACK could be a useful non-invasive clinical tool for assessing hemodynamics in brain AVMs. Key Points: • The 4D-MR angiography based on super-selective pseudo-continuous arterial spin labeling combined with CENTRA-keyhole and view-sharing (4D-S-PACK) enabled excellent vessel selectivity. • The 4D-S-PACK enabled the perfect identification of feeding arteries of brain arteriovenous malformation (AVM). • 4D-S-PACK could be a non-invasive clinical tool for assessing hemodynamics in brain AVMs. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00330-020-07057-4 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 12 StartPage: 6452 Subjects: – SubjectFull: Spin labels Type: general – SubjectFull: Digital subtraction angiography Type: general – SubjectFull: Cerebral arteriovenous malformations Type: general – SubjectFull: Angiography Type: general – SubjectFull: Magnetic resonance angiography Type: general Titles: – TitleFull: Vessel-selective 4D-MR angiography using super-selective pseudo-continuous arterial spin labeling may be a useful tool for assessing brain AVM hemodynamics. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Togao, Osamu – PersonEntity: Name: NameFull: Obara, Makoto – PersonEntity: Name: NameFull: Helle, Michael – PersonEntity: Name: NameFull: Yamashita, Koji – PersonEntity: Name: NameFull: Kikuchi, Kazufumi – PersonEntity: Name: NameFull: Momosaka, Daichi – PersonEntity: Name: NameFull: Kikuchi, Yoshitomo – PersonEntity: Name: NameFull: Nishimura, Ataru – PersonEntity: Name: NameFull: Arimura, Koichi – PersonEntity: Name: NameFull: Wada, Tatsuhiro – PersonEntity: Name: NameFull: Murazaki, Hiroo – PersonEntity: Name: NameFull: Iihara, Koji – PersonEntity: Name: NameFull: Van Cauteren, Marc – PersonEntity: Name: NameFull: Hiwatashi, Akio IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: Dec2020 Type: published Y: 2020 Identifiers: – Type: issn-print Value: 09387994 Numbering: – Type: volume Value: 30 – Type: issue Value: 12 Titles: – TitleFull: European Radiology Type: main |
| ResultId | 1 |
