High spatial resolution spiral first‐pass myocardial perfusion imaging with whole‐heart coverage at 3 T.
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| Title: | High spatial resolution spiral first‐pass myocardial perfusion imaging with whole‐heart coverage at 3 T. |
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| Authors: | Wang, Junyu1 (AUTHOR), Yang, Yang2,3 (AUTHOR), Weller, Daniel S.4 (AUTHOR), Zhou, Ruixi1 (AUTHOR), Van Houten, Matthew1 (AUTHOR), Sun, Changyu1 (AUTHOR), Epstein, Frederick H.1,5 (AUTHOR), Meyer, Craig H.1,5 (AUTHOR), Kramer, Christopher M.3,5 (AUTHOR), Salerno, Michael1,3,5 (AUTHOR) ms5pc@virginia.edu |
| Source: | Magnetic Resonance in Medicine. Aug2021, Vol. 86 Issue 2, p648-662. 15p. |
| Subjects: | Myocardial perfusion imaging, High resolution imaging, Coronary disease, Endocardium |
| Abstract: | Purpose: To develop and evaluate a high spatial resolution (1.25 × 1.25 mm2) spiral first‐pass myocardial perfusion imaging technique with whole‐heart coverage at 3T, to better assess transmural differences in perfusion between the endocardium and epicardium, to quantify the myocardial ischemic burden, and to improve the detection of obstructive coronary artery disease. Methods: Whole‐heart high‐resolution spiral perfusion pulse sequences and corresponding motion‐compensated reconstruction techniques for both interleaved single‐slice (SS) and simultaneous multi‐slice (SMS) acquisition with or without outer‐volume suppression (OVS) were developed. The proposed techniques were evaluated in 34 healthy volunteers and 8 patients (55 data sets). SS and SMS images were reconstructed using motion‐compensated L1‐SPIRiT and SMS‐Slice‐L1‐SPIRiT, respectively. Images were blindly graded by 2 experienced cardiologists on a 5‐point scale (5, excellent; 1, poor). Results: High‐quality perfusion imaging was achieved for both SS and SMS acquisitions with or without OVS. The SS technique without OVS had the highest scores (4.5 [4, 5]), which were greater than scores for SS with OVS (3.5 [3.25, 3.75], P <.05), MB = 2 without OVS (3.75 [3.25, 4], P <.05), and MB = 2 with OVS (3.75 [2.75, 4], P <.05), but significantly higher than those for MB = 3 without OVS (4 [4, 4], P =.95). SMS image quality was improved using SMS‐Slice‐L1‐SPIRiT as compared to SMS‐L1‐SPIRiT (P <.05 for both reviewers). Conclusion: We demonstrated the successful implementation of whole‐heart spiral perfusion imaging with high resolution at 3T. Good image quality was achieved, and the SS without OVS showed the best image quality. Evaluation in patients with expected ischemic heart disease is warranted. [ABSTRACT FROM AUTHOR] |
| Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Header | DbId: egs DbLabel: Engineering Source An: 150003488 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: High spatial resolution spiral first‐pass myocardial perfusion imaging with whole‐heart coverage at 3 T. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Wang%2C+Junyu%22">Wang, Junyu</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yang%2C+Yang%22">Yang, Yang</searchLink><relatesTo>2,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Weller%2C+Daniel+S%2E%22">Weller, Daniel S.</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhou%2C+Ruixi%22">Zhou, Ruixi</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Van+Houten%2C+Matthew%22">Van Houten, Matthew</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sun%2C+Changyu%22">Sun, Changyu</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Epstein%2C+Frederick+H%2E%22">Epstein, Frederick H.</searchLink><relatesTo>1,5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Meyer%2C+Craig+H%2E%22">Meyer, Craig H.</searchLink><relatesTo>1,5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kramer%2C+Christopher+M%2E%22">Kramer, Christopher M.</searchLink><relatesTo>3,5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Salerno%2C+Michael%22">Salerno, Michael</searchLink><relatesTo>1,3,5</relatesTo> (AUTHOR)<i> ms5pc@virginia.edu</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Magnetic+Resonance+in+Medicine%22">Magnetic Resonance in Medicine</searchLink>. Aug2021, Vol. 86 Issue 2, p648-662. 15p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Myocardial+perfusion+imaging%22">Myocardial perfusion imaging</searchLink><br /><searchLink fieldCode="DE" term="%22High+resolution+imaging%22">High resolution imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Coronary+disease%22">Coronary disease</searchLink><br /><searchLink fieldCode="DE" term="%22Endocardium%22">Endocardium</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Purpose: To develop and evaluate a high spatial resolution (1.25 × 1.25 mm2) spiral first‐pass myocardial perfusion imaging technique with whole‐heart coverage at 3T, to better assess transmural differences in perfusion between the endocardium and epicardium, to quantify the myocardial ischemic burden, and to improve the detection of obstructive coronary artery disease. Methods: Whole‐heart high‐resolution spiral perfusion pulse sequences and corresponding motion‐compensated reconstruction techniques for both interleaved single‐slice (SS) and simultaneous multi‐slice (SMS) acquisition with or without outer‐volume suppression (OVS) were developed. The proposed techniques were evaluated in 34 healthy volunteers and 8 patients (55 data sets). SS and SMS images were reconstructed using motion‐compensated L1‐SPIRiT and SMS‐Slice‐L1‐SPIRiT, respectively. Images were blindly graded by 2 experienced cardiologists on a 5‐point scale (5, excellent; 1, poor). Results: High‐quality perfusion imaging was achieved for both SS and SMS acquisitions with or without OVS. The SS technique without OVS had the highest scores (4.5 [4, 5]), which were greater than scores for SS with OVS (3.5 [3.25, 3.75], P <.05), MB = 2 without OVS (3.75 [3.25, 4], P <.05), and MB = 2 with OVS (3.75 [2.75, 4], P <.05), but significantly higher than those for MB = 3 without OVS (4 [4, 4], P =.95). SMS image quality was improved using SMS‐Slice‐L1‐SPIRiT as compared to SMS‐L1‐SPIRiT (P <.05 for both reviewers). Conclusion: We demonstrated the successful implementation of whole‐heart spiral perfusion imaging with high resolution at 3T. Good image quality was achieved, and the SS without OVS showed the best image quality. Evaluation in patients with expected ischemic heart disease is warranted. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/mrm.28701 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 15 StartPage: 648 Subjects: – SubjectFull: Myocardial perfusion imaging Type: general – SubjectFull: High resolution imaging Type: general – SubjectFull: Coronary disease Type: general – SubjectFull: Endocardium Type: general Titles: – TitleFull: High spatial resolution spiral first‐pass myocardial perfusion imaging with whole‐heart coverage at 3 T. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wang, Junyu – PersonEntity: Name: NameFull: Yang, Yang – PersonEntity: Name: NameFull: Weller, Daniel S. – PersonEntity: Name: NameFull: Zhou, Ruixi – PersonEntity: Name: NameFull: Van Houten, Matthew – PersonEntity: Name: NameFull: Sun, Changyu – PersonEntity: Name: NameFull: Epstein, Frederick H. – PersonEntity: Name: NameFull: Meyer, Craig H. – PersonEntity: Name: NameFull: Kramer, Christopher M. – PersonEntity: Name: NameFull: Salerno, Michael IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: Aug2021 Type: published Y: 2021 Identifiers: – Type: issn-print Value: 07403194 Numbering: – Type: volume Value: 86 – Type: issue Value: 2 Titles: – TitleFull: Magnetic Resonance in Medicine Type: main |
| ResultId | 1 |
