The use of photobiomodulation therapy or LED and mineral trioxide aggregate improves the repair of complete tibial fractures treated with wire osteosynthesis in rodents.
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| Title: | The use of photobiomodulation therapy or LED and mineral trioxide aggregate improves the repair of complete tibial fractures treated with wire osteosynthesis in rodents. |
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| Authors: | Pinheiro, Antônio L. B.1,2,3 albp@ufba.br, Soares, Luiz G. P.1,2,4, da Silva, Aline C. P.1, Santos, Nicole R. S.1, da Silva, Anna Paula L. T.1, Neves, Bruno Luiz R. C.1, Soares, Amanda P.1, Gerbi, Marleny Elizabeth M. M.5, dos Santos, Jean Nunes6 |
| Source: | Lasers in Medical Science. Jun2021, Vol. 36 Issue 4, p735-742. 8p. |
| Subjects: | Bone abnormalities, Biomaterials, Histomorphometry, Phototherapy, Microscopy |
| Abstract: | The repair of large bone defects is lengthy and complex. Both biomaterials and phototherapy have been used to improve bone repair. We aimed to describe histologically the repair of tibial fractures treated by wiring (W), irradiated or not, with laser (λ780 nm, 70 mW, CW, spot area of 0.5 cm2, 20.4 J/cm2 (4 × 5.1 J/cm2, Twin Flex Evolution®, MM Optics, Sao Carlos, SP, Brazil) per session, 300 s, 142.8 J/cm2 per treatment) or LED (λ850 ± 10 nm, 150 mW, spot area of 0.5 cm2, 20.4 J/cm2 per session, 64 s, 142.8 J/cm2 per treatment, Fisioled®, MM Optics, Sao Carlos, Sao Paulo, Brazil) and associated or not to the use of mineral trioxide aggregate (MTA, Angelus®, Londrina, PR, Brazil). Inflammation was discrete on groups W and W + LEDPT and absent on the others. Phototherapy protocols started immediately before suturing and repeated at every other day for 15 days. Collagen deposition intense on groups W + LEDPT, W + BIO-MTA + LaserPT and W + BIO-MTA + LEDPT and discrete or moderate on the other groups. Reabsorption was discrete on groups W and W + LEDPT and absent on the other groups. Neoformation varied greatly between groups. Most groups were partial and moderately filed with new-formed bone (W, W + LaserPT, W + LEDPT, W + BIO-MTA + LEDPT). On groups W + BIO-MTA and W + BIO-MTA + LaserPT bone, neoformation was intense and complete. Our results are indicative that the association of MTA and PBMT (λ = 780 nm) improves the repair of complete tibial fracture treated with wire osteosynthesis in a rodent model more efficiently than LED (λ = 850 ± 10 nm). [ABSTRACT FROM AUTHOR] |
| Copyright of Lasers in Medical Science is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 150305113 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The use of photobiomodulation therapy or LED and mineral trioxide aggregate improves the repair of complete tibial fractures treated with wire osteosynthesis in rodents. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Pinheiro%2C+Antônio+L%2E+B%2E%22">Pinheiro, Antônio L. B.</searchLink><relatesTo>1,2,3</relatesTo><i> albp@ufba.br</i><br /><searchLink fieldCode="AR" term="%22Soares%2C+Luiz+G%2E+P%2E%22">Soares, Luiz G. P.</searchLink><relatesTo>1,2,4</relatesTo><br /><searchLink fieldCode="AR" term="%22da+Silva%2C+Aline+C%2E+P%2E%22">da Silva, Aline C. P.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Santos%2C+Nicole+R%2E+S%2E%22">Santos, Nicole R. S.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22da+Silva%2C+Anna+Paula+L%2E+T%2E%22">da Silva, Anna Paula L. T.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Neves%2C+Bruno+Luiz+R%2E+C%2E%22">Neves, Bruno Luiz R. C.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Soares%2C+Amanda+P%2E%22">Soares, Amanda P.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Gerbi%2C+Marleny+Elizabeth+M%2E+M%2E%22">Gerbi, Marleny Elizabeth M. M.</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22dos+Santos%2C+Jean+Nunes%22">dos Santos, Jean Nunes</searchLink><relatesTo>6</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Lasers+in+Medical+Science%22">Lasers in Medical Science</searchLink>. Jun2021, Vol. 36 Issue 4, p735-742. 8p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Bone+abnormalities%22">Bone abnormalities</searchLink><br /><searchLink fieldCode="DE" term="%22Biomaterials%22">Biomaterials</searchLink><br /><searchLink fieldCode="DE" term="%22Histomorphometry%22">Histomorphometry</searchLink><br /><searchLink fieldCode="DE" term="%22Phototherapy%22">Phototherapy</searchLink><br /><searchLink fieldCode="DE" term="%22Microscopy%22">Microscopy</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: The repair of large bone defects is lengthy and complex. Both biomaterials and phototherapy have been used to improve bone repair. We aimed to describe histologically the repair of tibial fractures treated by wiring (W), irradiated or not, with laser (λ780 nm, 70 mW, CW, spot area of 0.5 cm2, 20.4 J/cm2 (4 × 5.1 J/cm2, Twin Flex Evolution®, MM Optics, Sao Carlos, SP, Brazil) per session, 300 s, 142.8 J/cm2 per treatment) or LED (λ850 ± 10 nm, 150 mW, spot area of 0.5 cm2, 20.4 J/cm2 per session, 64 s, 142.8 J/cm2 per treatment, Fisioled®, MM Optics, Sao Carlos, Sao Paulo, Brazil) and associated or not to the use of mineral trioxide aggregate (MTA, Angelus®, Londrina, PR, Brazil). Inflammation was discrete on groups W and W + LEDPT and absent on the others. Phototherapy protocols started immediately before suturing and repeated at every other day for 15 days. Collagen deposition intense on groups W + LEDPT, W + BIO-MTA + LaserPT and W + BIO-MTA + LEDPT and discrete or moderate on the other groups. Reabsorption was discrete on groups W and W + LEDPT and absent on the other groups. Neoformation varied greatly between groups. Most groups were partial and moderately filed with new-formed bone (W, W + LaserPT, W + LEDPT, W + BIO-MTA + LEDPT). On groups W + BIO-MTA and W + BIO-MTA + LaserPT bone, neoformation was intense and complete. Our results are indicative that the association of MTA and PBMT (λ = 780 nm) improves the repair of complete tibial fracture treated with wire osteosynthesis in a rodent model more efficiently than LED (λ = 850 ± 10 nm). [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Lasers in Medical Science is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=150305113 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10103-020-03074-3 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 735 Subjects: – SubjectFull: Bone abnormalities Type: general – SubjectFull: Biomaterials Type: general – SubjectFull: Histomorphometry Type: general – SubjectFull: Phototherapy Type: general – SubjectFull: Microscopy Type: general Titles: – TitleFull: The use of photobiomodulation therapy or LED and mineral trioxide aggregate improves the repair of complete tibial fractures treated with wire osteosynthesis in rodents. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Pinheiro, Antônio L. B. – PersonEntity: Name: NameFull: Soares, Luiz G. P. – PersonEntity: Name: NameFull: da Silva, Aline C. P. – PersonEntity: Name: NameFull: Santos, Nicole R. S. – PersonEntity: Name: NameFull: da Silva, Anna Paula L. T. – PersonEntity: Name: NameFull: Neves, Bruno Luiz R. C. – PersonEntity: Name: NameFull: Soares, Amanda P. – PersonEntity: Name: NameFull: Gerbi, Marleny Elizabeth M. M. – PersonEntity: Name: NameFull: dos Santos, Jean Nunes IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: Jun2021 Type: published Y: 2021 Identifiers: – Type: issn-print Value: 02688921 Numbering: – Type: volume Value: 36 – Type: issue Value: 4 Titles: – TitleFull: Lasers in Medical Science Type: main |
| ResultId | 1 |
