1,3‐Dioleoyl‐2‐palmitoyl glycerol (OPO)—Enzymatic synthesis and use as an important supplement in infant formulas.
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| Title: | 1,3‐Dioleoyl‐2‐palmitoyl glycerol (OPO)—Enzymatic synthesis and use as an important supplement in infant formulas. |
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| Authors: | Ghide, Michael Kidane1 (AUTHOR), Yan, Yunjun1 (AUTHOR) yanyunjun@hust.edu.cn |
| Source: | Journal of Food Biochemistry. Jul2021, Vol. 45 Issue 7, p1-13. 13p. |
| Subjects: | Infant formulas, Milk substitutes, Milkfat, Breast milk, Fat substitutes, Lipases, Infant growth |
| Abstract: | 1,3‐dioleolyl‐2‐palmitate (OPO) is an important component of the human milk fat. Its unique fatty acid composition and distribution play an important role in proper infant growth and development. Owing to this, it has been attracting researchers and manufacturers to synthesize and commercialize OPO as an important human milk fat substitute added to infant formulas. In this review, the role of OPO in human milk, the benefits of OPO (sn‐2 palmitate)‐supplemented infant formulas over the conventional infant formulas on infant growth, and lipase‐catalyzed synthesis of OPO are discussed. Over the last 20 years of research on the benefits of OPO (sn2 palmitate)‐supplemented infant formulas are summarized. Similarly, studies carried out on lipase catalyzed production of OPO for the last 21 years (1999–2019) are also done focusing on the raw materials, sn1,3‐regiospecific lipases, immobilization materials, and solvents used in the laboratory‐scale experiments. In addition, OPO‐based products currently in the market and future research trends are briefly covered in this review. Practical applications: This work focuses on lipase‐catalyzed synthesis of 1,3‐dioleoyl‐2‐palmitoylglycerol (the most abundant triacyl glycerol in human milk fat) and its benefits to infants when it is added in infant formulas. Over the last 20 years of published research from the literature are summarized and future research trends for efficient OPO synthesis are also covered. This will provide current and future researchers on the field with the necessary background information on OPO synthesis and design their research plans accordingly for cost‐effective production of OPO and OPO‐supplemented infant formulas. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Food Biochemistry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Header | DbId: egs DbLabel: Engineering Source An: 151209521 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: 1,3‐Dioleoyl‐2‐palmitoyl glycerol (OPO)—Enzymatic synthesis and use as an important supplement in infant formulas. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Ghide%2C+Michael+Kidane%22">Ghide, Michael Kidane</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yan%2C+Yunjun%22">Yan, Yunjun</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> yanyunjun@hust.edu.cn</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Food+Biochemistry%22">Journal of Food Biochemistry</searchLink>. Jul2021, Vol. 45 Issue 7, p1-13. 13p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Infant+formulas%22">Infant formulas</searchLink><br /><searchLink fieldCode="DE" term="%22Milk+substitutes%22">Milk substitutes</searchLink><br /><searchLink fieldCode="DE" term="%22Milkfat%22">Milkfat</searchLink><br /><searchLink fieldCode="DE" term="%22Breast+milk%22">Breast milk</searchLink><br /><searchLink fieldCode="DE" term="%22Fat+substitutes%22">Fat substitutes</searchLink><br /><searchLink fieldCode="DE" term="%22Lipases%22">Lipases</searchLink><br /><searchLink fieldCode="DE" term="%22Infant+growth%22">Infant growth</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: 1,3‐dioleolyl‐2‐palmitate (OPO) is an important component of the human milk fat. Its unique fatty acid composition and distribution play an important role in proper infant growth and development. Owing to this, it has been attracting researchers and manufacturers to synthesize and commercialize OPO as an important human milk fat substitute added to infant formulas. In this review, the role of OPO in human milk, the benefits of OPO (sn‐2 palmitate)‐supplemented infant formulas over the conventional infant formulas on infant growth, and lipase‐catalyzed synthesis of OPO are discussed. Over the last 20 years of research on the benefits of OPO (sn2 palmitate)‐supplemented infant formulas are summarized. Similarly, studies carried out on lipase catalyzed production of OPO for the last 21 years (1999–2019) are also done focusing on the raw materials, sn1,3‐regiospecific lipases, immobilization materials, and solvents used in the laboratory‐scale experiments. In addition, OPO‐based products currently in the market and future research trends are briefly covered in this review. Practical applications: This work focuses on lipase‐catalyzed synthesis of 1,3‐dioleoyl‐2‐palmitoylglycerol (the most abundant triacyl glycerol in human milk fat) and its benefits to infants when it is added in infant formulas. Over the last 20 years of published research from the literature are summarized and future research trends for efficient OPO synthesis are also covered. This will provide current and future researchers on the field with the necessary background information on OPO synthesis and design their research plans accordingly for cost‐effective production of OPO and OPO‐supplemented infant formulas. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Food Biochemistry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/jfbc.13799 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 13 StartPage: 1 Subjects: – SubjectFull: Infant formulas Type: general – SubjectFull: Milk substitutes Type: general – SubjectFull: Milkfat Type: general – SubjectFull: Breast milk Type: general – SubjectFull: Fat substitutes Type: general – SubjectFull: Lipases Type: general – SubjectFull: Infant growth Type: general Titles: – TitleFull: 1,3‐Dioleoyl‐2‐palmitoyl glycerol (OPO)—Enzymatic synthesis and use as an important supplement in infant formulas. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ghide, Michael Kidane – PersonEntity: Name: NameFull: Yan, Yunjun IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: Jul2021 Type: published Y: 2021 Identifiers: – Type: issn-print Value: 01458884 Numbering: – Type: volume Value: 45 – Type: issue Value: 7 Titles: – TitleFull: Journal of Food Biochemistry Type: main |
| ResultId | 1 |
