Promotion of the Wound Healing of in vivo Rabbit Wound Infected With Methicillin-Resistant Staphylococcus aureus Treated by a Cold Atmospheric Plasma Jet.
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| Title: | Promotion of the Wound Healing of in vivo Rabbit Wound Infected With Methicillin-Resistant Staphylococcus aureus Treated by a Cold Atmospheric Plasma Jet. |
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| Authors: | Li, Guiling1, Li, Donghai2, Li, Jing3, Jia, Ya-Nan4, Zhu, Chenqi5, Zhang, Yu1 yuzhang2014@tsinghua.edu.cn, Li, He-Ping3 liheping@tsinghua.edu.cn |
| Source: | IEEE Transactions on Plasma Science. Aug2021, Vol. 49 Issue 8, p2329-2339. 11p. |
| Subjects: | Plasma jets, Wound healing, Methicillin-resistant staphylococcus aureus, Low temperature plasmas, Helium plasmas, Bacterial inactivation |
| Abstract: | Surgical incision infection of multidrug-resistant microorganisms (e.g., methicillin-resistant Staphylococcus aureus, MRSA) is a severe cause of poor wound healing, which is prevalent in healthcare facilities and constitutes a huge infectious disease burden in the world. The purpose of this study is to investigate the medical application and possible mechanisms of the cold atmospheric plasma jet on infected wounds. In this article, the New Zealand rabbit in vivo wound infected with MRSA is used as the wound healing animal model. The helium atmospheric-pressure dielectric-barrier-discharge (AP-DBD) plasma jet is employed to treat the wounds infected with MRSA. The wound healing, histological, and cytokine analyses are conducted to evaluate the efficacy of the helium AP-DBD plasma jet on the MRSA-infected wound healing process. The experimental results show that the helium AP-DBD plasma jet treatment on the wounds infected with MRSA can regulate the secretion of the cytokines, limit the inflammatory response and cell excessive proliferation, accelerate the process of re-epithelialization, and consequently, promote the wound healing process and the inactivation of the bacteria. [ABSTRACT FROM AUTHOR] |
| Copyright of IEEE Transactions on Plasma Science is the property of IEEE and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 153764129 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Promotion of the Wound Healing of in vivo Rabbit Wound Infected With Methicillin-Resistant Staphylococcus aureus Treated by a Cold Atmospheric Plasma Jet. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Li%2C+Guiling%22">Li, Guiling</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Li%2C+Donghai%22">Li, Donghai</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Li%2C+Jing%22">Li, Jing</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Jia%2C+Ya-Nan%22">Jia, Ya-Nan</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Zhu%2C+Chenqi%22">Zhu, Chenqi</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Zhang%2C+Yu%22">Zhang, Yu</searchLink><relatesTo>1</relatesTo><i> yuzhang2014@tsinghua.edu.cn</i><br /><searchLink fieldCode="AR" term="%22Li%2C+He-Ping%22">Li, He-Ping</searchLink><relatesTo>3</relatesTo><i> liheping@tsinghua.edu.cn</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22IEEE+Transactions+on+Plasma+Science%22">IEEE Transactions on Plasma Science</searchLink>. Aug2021, Vol. 49 Issue 8, p2329-2339. 11p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Plasma+jets%22">Plasma jets</searchLink><br /><searchLink fieldCode="DE" term="%22Wound+healing%22">Wound healing</searchLink><br /><searchLink fieldCode="DE" term="%22Methicillin-resistant+staphylococcus+aureus%22">Methicillin-resistant staphylococcus aureus</searchLink><br /><searchLink fieldCode="DE" term="%22Low+temperature+plasmas%22">Low temperature plasmas</searchLink><br /><searchLink fieldCode="DE" term="%22Helium+plasmas%22">Helium plasmas</searchLink><br /><searchLink fieldCode="DE" term="%22Bacterial+inactivation%22">Bacterial inactivation</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Surgical incision infection of multidrug-resistant microorganisms (e.g., methicillin-resistant Staphylococcus aureus, MRSA) is a severe cause of poor wound healing, which is prevalent in healthcare facilities and constitutes a huge infectious disease burden in the world. The purpose of this study is to investigate the medical application and possible mechanisms of the cold atmospheric plasma jet on infected wounds. In this article, the New Zealand rabbit in vivo wound infected with MRSA is used as the wound healing animal model. The helium atmospheric-pressure dielectric-barrier-discharge (AP-DBD) plasma jet is employed to treat the wounds infected with MRSA. The wound healing, histological, and cytokine analyses are conducted to evaluate the efficacy of the helium AP-DBD plasma jet on the MRSA-infected wound healing process. The experimental results show that the helium AP-DBD plasma jet treatment on the wounds infected with MRSA can regulate the secretion of the cytokines, limit the inflammatory response and cell excessive proliferation, accelerate the process of re-epithelialization, and consequently, promote the wound healing process and the inactivation of the bacteria. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of IEEE Transactions on Plasma Science is the property of IEEE and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1109/TPS.2021.3092946 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 11 StartPage: 2329 Subjects: – SubjectFull: Plasma jets Type: general – SubjectFull: Wound healing Type: general – SubjectFull: Methicillin-resistant staphylococcus aureus Type: general – SubjectFull: Low temperature plasmas Type: general – SubjectFull: Helium plasmas Type: general – SubjectFull: Bacterial inactivation Type: general Titles: – TitleFull: Promotion of the Wound Healing of in vivo Rabbit Wound Infected With Methicillin-Resistant Staphylococcus aureus Treated by a Cold Atmospheric Plasma Jet. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Li, Guiling – PersonEntity: Name: NameFull: Li, Donghai – PersonEntity: Name: NameFull: Li, Jing – PersonEntity: Name: NameFull: Jia, Ya-Nan – PersonEntity: Name: NameFull: Zhu, Chenqi – PersonEntity: Name: NameFull: Zhang, Yu – PersonEntity: Name: NameFull: Li, He-Ping IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: Aug2021 Type: published Y: 2021 Identifiers: – Type: issn-print Value: 00933813 Numbering: – Type: volume Value: 49 – Type: issue Value: 8 Titles: – TitleFull: IEEE Transactions on Plasma Science Type: main |
| ResultId | 1 |
