Methods of monitoring thermal ablation of soft tissue tumors – A comprehensive review.
Saved in:
| Title: | Methods of monitoring thermal ablation of soft tissue tumors – A comprehensive review. |
|---|---|
| Authors: | Geoghegan, Rory1 (AUTHOR) rory.geoghegan@ucla.edu, ter Haar, Gail2 (AUTHOR), Nightingale, Kathryn3 (AUTHOR), Marks, Leonard1 (AUTHOR), Natarajan, Shyam4 (AUTHOR) |
| Source: | Medical Physics. Feb2022, Vol. 49 Issue 2, p769-791. 23p. |
| Subjects: | Soft tissue tumors, Tissue mechanics, Damage models, Optical properties, Catheter ablation, Tissues |
| Abstract: | Thermal ablation is a form of hyperthermia in which oncologic control can be achieved by briefly inducing elevated temperatures, typically in the range 50–80°C, within a target tissue. Ablation modalities include high intensity focused ultrasound, radiofrequency ablation, microwave ablation, and laser interstitial thermal therapy which are all capable of generating confined zones of tissue destruction, resulting in fewer complications than conventional cancer therapies. Oncologic control is contingent upon achieving predefined coagulation zones; therefore, intraoperative assessment of treatment progress is highly desirable. Consequently, there is a growing interest in the development of ablation monitoring modalities. The first section of this review presents the mechanism of action and common applications of the primary ablation modalities. The following section outlines the state‐of‐the‐art in thermal dosimetry which includes interstitial thermal probes and radiologic imaging. Both the physical mechanism of measurement and clinical or pre‐clinical performance are discussed for each ablation modality. Thermal dosimetry must be coupled with a thermal damage model as outlined in Section 4. These models estimate cell death based on temperature‐time history and are inherently tissue specific. In the absence of a reliable thermal model, the utility of thermal monitoring is greatly reduced. The final section of this review paper covers technologies that have been developed to directly assess tissue conditions. These approaches include visualization of non‐perfused tissue with contrast‐enhanced imaging, assessment of tissue mechanical properties using ultrasound and magnetic resonance elastography, and finally interrogation of tissue optical properties with interstitial probes. In summary, monitoring thermal ablation is critical for consistent clinical success and many promising technologies are under development but an optimal solution has yet to achieve widespread adoption. [ABSTRACT FROM AUTHOR] |
| Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
|
Full text is not displayed to guests.
Login for full access.
|
|
| FullText | Links: – Type: pdflink Text: Availability: 1 |
|---|---|
| Header | DbId: egs DbLabel: Engineering Source An: 155147397 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Methods of monitoring thermal ablation of soft tissue tumors – A comprehensive review. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Geoghegan%2C+Rory%22">Geoghegan, Rory</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> rory.geoghegan@ucla.edu</i><br /><searchLink fieldCode="AR" term="%22ter+Haar%2C+Gail%22">ter Haar, Gail</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nightingale%2C+Kathryn%22">Nightingale, Kathryn</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Marks%2C+Leonard%22">Marks, Leonard</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Natarajan%2C+Shyam%22">Natarajan, Shyam</searchLink><relatesTo>4</relatesTo> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Medical+Physics%22">Medical Physics</searchLink>. Feb2022, Vol. 49 Issue 2, p769-791. 23p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Soft+tissue+tumors%22">Soft tissue tumors</searchLink><br /><searchLink fieldCode="DE" term="%22Tissue+mechanics%22">Tissue mechanics</searchLink><br /><searchLink fieldCode="DE" term="%22Damage+models%22">Damage models</searchLink><br /><searchLink fieldCode="DE" term="%22Optical+properties%22">Optical properties</searchLink><br /><searchLink fieldCode="DE" term="%22Catheter+ablation%22">Catheter ablation</searchLink><br /><searchLink fieldCode="DE" term="%22Tissues%22">Tissues</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Thermal ablation is a form of hyperthermia in which oncologic control can be achieved by briefly inducing elevated temperatures, typically in the range 50–80°C, within a target tissue. Ablation modalities include high intensity focused ultrasound, radiofrequency ablation, microwave ablation, and laser interstitial thermal therapy which are all capable of generating confined zones of tissue destruction, resulting in fewer complications than conventional cancer therapies. Oncologic control is contingent upon achieving predefined coagulation zones; therefore, intraoperative assessment of treatment progress is highly desirable. Consequently, there is a growing interest in the development of ablation monitoring modalities. The first section of this review presents the mechanism of action and common applications of the primary ablation modalities. The following section outlines the state‐of‐the‐art in thermal dosimetry which includes interstitial thermal probes and radiologic imaging. Both the physical mechanism of measurement and clinical or pre‐clinical performance are discussed for each ablation modality. Thermal dosimetry must be coupled with a thermal damage model as outlined in Section 4. These models estimate cell death based on temperature‐time history and are inherently tissue specific. In the absence of a reliable thermal model, the utility of thermal monitoring is greatly reduced. The final section of this review paper covers technologies that have been developed to directly assess tissue conditions. These approaches include visualization of non‐perfused tissue with contrast‐enhanced imaging, assessment of tissue mechanical properties using ultrasound and magnetic resonance elastography, and finally interrogation of tissue optical properties with interstitial probes. In summary, monitoring thermal ablation is critical for consistent clinical success and many promising technologies are under development but an optimal solution has yet to achieve widespread adoption. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Medical Physics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=155147397 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/mp.15439 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 23 StartPage: 769 Subjects: – SubjectFull: Soft tissue tumors Type: general – SubjectFull: Tissue mechanics Type: general – SubjectFull: Damage models Type: general – SubjectFull: Optical properties Type: general – SubjectFull: Catheter ablation Type: general – SubjectFull: Tissues Type: general Titles: – TitleFull: Methods of monitoring thermal ablation of soft tissue tumors – A comprehensive review. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Geoghegan, Rory – PersonEntity: Name: NameFull: ter Haar, Gail – PersonEntity: Name: NameFull: Nightingale, Kathryn – PersonEntity: Name: NameFull: Marks, Leonard – PersonEntity: Name: NameFull: Natarajan, Shyam IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: Feb2022 Type: published Y: 2022 Identifiers: – Type: issn-print Value: 00942405 Numbering: – Type: volume Value: 49 – Type: issue Value: 2 Titles: – TitleFull: Medical Physics Type: main |
| ResultId | 1 |
