View in EDS

The anti-inflammatory and osteogenic activity of chitosan/polyvinyl alcohol/graphene oxide/astaxanthin nanofibers membranes in vitro study.

Saved in:
Bibliographic Details
Title: The anti-inflammatory and osteogenic activity of chitosan/polyvinyl alcohol/graphene oxide/astaxanthin nanofibers membranes in vitro study.
Authors: Dang, Xuan1 (AUTHOR), Zhang, Hengfang1 (AUTHOR), Lin, Lexun2 (AUTHOR), Li, Pie1 (AUTHOR), Ren, Liping1 (AUTHOR), Zhang, Wei3 (AUTHOR), Song, Rong1 (AUTHOR) songrong1977@126.com
Source: Journal of Biomaterials Applications. May2022, Vol. 36 Issue 10, p1873-1881. 9p.
Subjects: Astaxanthin, Polyvinyl alcohol, Graphene oxide, Nanofibers, Anti-inflammatory agents, Chitosan, Mesenchymal stem cells
Abstract: Anti-inflammation and bone regeneration are the two major goals of periodontal therapy. We have demonstrated that chitosan (CS)/polyvinyl alcohol (PVA)/graphene oxide (GO)/astaxanthin (ASTA) nanofibers membranes prepared by electrospinning had favorable micro-morphology, good mechanical properties, and no cytotoxicity. In this study, CS/PVA/GO/ASTA nanofibers membranes were prepared to modulate both inflammatory response and osteogenic induction in vitro study. When the nanofibers membranes were co-cultured with RAW264.7 cells, glycoprotein nonmetastatic melanoma protein in the cells was highly expressed and RAW264.7 cells were polarized to M2 phenotype at the same time. In addition, following stimulation with nanofibers membranes, the messenger RNA (mRNA) and protein levels of Osteocalcin (OCN) and Runx2 in Bone marrow mesenchymal stem cells (BMSCs) were highly expressed. Taken together, these results suggested CS/PVA/GO/ASTA nanofibers membranes may promote the dissipation of inflammation and stimulate the differentiation of BMSCs into osteoblasts. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Biomaterials Applications is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 156187697
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: The anti-inflammatory and osteogenic activity of chitosan/polyvinyl alcohol/graphene oxide/astaxanthin nanofibers membranes in vitro study.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Dang%2C+Xuan%22">Dang, Xuan</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhang%2C+Hengfang%22">Zhang, Hengfang</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lin%2C+Lexun%22">Lin, Lexun</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Li%2C+Pie%22">Li, Pie</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ren%2C+Liping%22">Ren, Liping</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhang%2C+Wei%22">Zhang, Wei</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Song%2C+Rong%22">Song, Rong</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> songrong1977@126.com</i>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Journal+of+Biomaterials+Applications%22">Journal of Biomaterials Applications</searchLink>. May2022, Vol. 36 Issue 10, p1873-1881. 9p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Astaxanthin%22">Astaxanthin</searchLink><br /><searchLink fieldCode="DE" term="%22Polyvinyl+alcohol%22">Polyvinyl alcohol</searchLink><br /><searchLink fieldCode="DE" term="%22Graphene+oxide%22">Graphene oxide</searchLink><br /><searchLink fieldCode="DE" term="%22Nanofibers%22">Nanofibers</searchLink><br /><searchLink fieldCode="DE" term="%22Anti-inflammatory+agents%22">Anti-inflammatory agents</searchLink><br /><searchLink fieldCode="DE" term="%22Chitosan%22">Chitosan</searchLink><br /><searchLink fieldCode="DE" term="%22Mesenchymal+stem+cells%22">Mesenchymal stem cells</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Anti-inflammation and bone regeneration are the two major goals of periodontal therapy. We have demonstrated that chitosan (CS)/polyvinyl alcohol (PVA)/graphene oxide (GO)/astaxanthin (ASTA) nanofibers membranes prepared by electrospinning had favorable micro-morphology, good mechanical properties, and no cytotoxicity. In this study, CS/PVA/GO/ASTA nanofibers membranes were prepared to modulate both inflammatory response and osteogenic induction in vitro study. When the nanofibers membranes were co-cultured with RAW264.7 cells, glycoprotein nonmetastatic melanoma protein in the cells was highly expressed and RAW264.7 cells were polarized to M2 phenotype at the same time. In addition, following stimulation with nanofibers membranes, the messenger RNA (mRNA) and protein levels of Osteocalcin (OCN) and Runx2 in Bone marrow mesenchymal stem cells (BMSCs) were highly expressed. Taken together, these results suggested CS/PVA/GO/ASTA nanofibers membranes may promote the dissipation of inflammation and stimulate the differentiation of BMSCs into osteoblasts. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Biomaterials Applications is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=156187697
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1177/08853282221076229
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 9
        StartPage: 1873
    Subjects:
      – SubjectFull: Astaxanthin
        Type: general
      – SubjectFull: Polyvinyl alcohol
        Type: general
      – SubjectFull: Graphene oxide
        Type: general
      – SubjectFull: Nanofibers
        Type: general
      – SubjectFull: Anti-inflammatory agents
        Type: general
      – SubjectFull: Chitosan
        Type: general
      – SubjectFull: Mesenchymal stem cells
        Type: general
    Titles:
      – TitleFull: The anti-inflammatory and osteogenic activity of chitosan/polyvinyl alcohol/graphene oxide/astaxanthin nanofibers membranes in vitro study.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Dang, Xuan
      – PersonEntity:
          Name:
            NameFull: Zhang, Hengfang
      – PersonEntity:
          Name:
            NameFull: Lin, Lexun
      – PersonEntity:
          Name:
            NameFull: Li, Pie
      – PersonEntity:
          Name:
            NameFull: Ren, Liping
      – PersonEntity:
          Name:
            NameFull: Zhang, Wei
      – PersonEntity:
          Name:
            NameFull: Song, Rong
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 05
              Text: May2022
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-print
              Value: 08853282
          Numbering:
            – Type: volume
              Value: 36
            – Type: issue
              Value: 10
          Titles:
            – TitleFull: Journal of Biomaterials Applications
              Type: main
ResultId 1