Enzyme engineering and its industrial applications.
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| Title: | Enzyme engineering and its industrial applications. |
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| Authors: | Victorino da Silva Amatto, Isabela1,2 (AUTHOR), Gonsales da Rosa‐Garzon, Nathalia1 (AUTHOR), Antônio de Oliveira Simões, Flávio1,3 (AUTHOR), Santiago, Fernanda1,2 (AUTHOR), Pereira da Silva Leite, Nathália4 (AUTHOR), Raspante Martins, Júlia1,2 (AUTHOR), Cabral, Hamilton1,2,3 (AUTHOR) hamilton@fcfrp.usp.br |
| Source: | Biotechnology & Applied Biochemistry. Apr2022, Vol. 69 Issue 2, p389-409. 21p. |
| Subjects: | Industrial enzymology, Manufacturing processes |
| Abstract: | Recently, there has been an increase in the demand for enzymes with modified activity, specificity, and stability. Enzyme engineering is an important tool to meet the demand for enzymes adjusted to different industrial processes. Knowledge of the structure and function of enzymes guides the choice of the best strategy for engineering enzymes. Each enzyme engineering strategy, such as rational design, directed evolution, and semi‐rational design, has specific applications, as well as limitations, which must be considered when choosing a suitable strategy. Engineered enzymes can be optimized for different industrial applications by choosing the appropriate strategy. This review features engineered enzymes that have been applied in food, animal feed, pharmaceuticals, medical applications, bioremediation, biofuels, and detergents. [ABSTRACT FROM AUTHOR] |
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| Database: | Engineering Source |
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| Abstract: | Recently, there has been an increase in the demand for enzymes with modified activity, specificity, and stability. Enzyme engineering is an important tool to meet the demand for enzymes adjusted to different industrial processes. Knowledge of the structure and function of enzymes guides the choice of the best strategy for engineering enzymes. Each enzyme engineering strategy, such as rational design, directed evolution, and semi‐rational design, has specific applications, as well as limitations, which must be considered when choosing a suitable strategy. Engineered enzymes can be optimized for different industrial applications by choosing the appropriate strategy. This review features engineered enzymes that have been applied in food, animal feed, pharmaceuticals, medical applications, bioremediation, biofuels, and detergents. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 08854513 |
| DOI: | 10.1002/bab.2117 |
