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Enzyme engineering and its industrial applications.

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Title: Enzyme engineering and its industrial applications.
Authors: Victorino da Silva Amatto, Isabela1,2 (AUTHOR), Gonsales da Rosa‐Garzon, Nathalia1 (AUTHOR), Antônio de Oliveira Simões, Flávio1,3 (AUTHOR), Santiago, Fernanda1,2 (AUTHOR), Pereira da Silva Leite, Nathália4 (AUTHOR), Raspante Martins, Júlia1,2 (AUTHOR), Cabral, Hamilton1,2,3 (AUTHOR) hamilton@fcfrp.usp.br
Source: Biotechnology & Applied Biochemistry. Apr2022, Vol. 69 Issue 2, p389-409. 21p.
Subjects: Industrial enzymology, Manufacturing processes
Abstract: Recently, there has been an increase in the demand for enzymes with modified activity, specificity, and stability. Enzyme engineering is an important tool to meet the demand for enzymes adjusted to different industrial processes. Knowledge of the structure and function of enzymes guides the choice of the best strategy for engineering enzymes. Each enzyme engineering strategy, such as rational design, directed evolution, and semi‐rational design, has specific applications, as well as limitations, which must be considered when choosing a suitable strategy. Engineered enzymes can be optimized for different industrial applications by choosing the appropriate strategy. This review features engineered enzymes that have been applied in food, animal feed, pharmaceuticals, medical applications, bioremediation, biofuels, and detergents. [ABSTRACT FROM AUTHOR]
Copyright of Biotechnology & Applied Biochemistry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Enzyme engineering and its industrial applications.
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  Data: <searchLink fieldCode="AR" term="%22Victorino+da+Silva+Amatto%2C+Isabela%22">Victorino da Silva Amatto, Isabela</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gonsales+da+Rosa‐Garzon%2C+Nathalia%22">Gonsales da Rosa‐Garzon, Nathalia</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Antônio+de+Oliveira+Simões%2C+Flávio%22">Antônio de Oliveira Simões, Flávio</searchLink><relatesTo>1,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Santiago%2C+Fernanda%22">Santiago, Fernanda</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pereira+da+Silva+Leite%2C+Nathália%22">Pereira da Silva Leite, Nathália</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Raspante+Martins%2C+Júlia%22">Raspante Martins, Júlia</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cabral%2C+Hamilton%22">Cabral, Hamilton</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<i> hamilton@fcfrp.usp.br</i>
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  Data: <searchLink fieldCode="JN" term="%22Biotechnology+%26+Applied+Biochemistry%22">Biotechnology & Applied Biochemistry</searchLink>. Apr2022, Vol. 69 Issue 2, p389-409. 21p.
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  Data: <searchLink fieldCode="DE" term="%22Industrial+enzymology%22">Industrial enzymology</searchLink><br /><searchLink fieldCode="DE" term="%22Manufacturing+processes%22">Manufacturing processes</searchLink>
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  Data: Recently, there has been an increase in the demand for enzymes with modified activity, specificity, and stability. Enzyme engineering is an important tool to meet the demand for enzymes adjusted to different industrial processes. Knowledge of the structure and function of enzymes guides the choice of the best strategy for engineering enzymes. Each enzyme engineering strategy, such as rational design, directed evolution, and semi‐rational design, has specific applications, as well as limitations, which must be considered when choosing a suitable strategy. Engineered enzymes can be optimized for different industrial applications by choosing the appropriate strategy. This review features engineered enzymes that have been applied in food, animal feed, pharmaceuticals, medical applications, bioremediation, biofuels, and detergents. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Biotechnology & Applied Biochemistry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1002/bab.2117
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        Text: English
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              Text: Apr2022
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              Y: 2022
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