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The Diagnostic Performance of 18F-FDG PET/CT in Recurrent Pancreatic Cancer: A Systematic Review and Meta-analysis.

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Title: The Diagnostic Performance of 18F-FDG PET/CT in Recurrent Pancreatic Cancer: A Systematic Review and Meta-analysis.
Authors: A, Gu1 (AUTHOR), Shan, Yuezhan1 (AUTHOR), Huo, Huasong2 (AUTHOR), Ding, Chao1 (AUTHOR), Sun, Caixia1 (AUTHOR)
Source: Applied Bionics & Biomechanics. 6/15/2022, p1-7. 7p.
Subjects: Pancreatic cancer, Fluorodeoxyglucose F18, Cancer relapse, Cancer diagnosis, Pancreatic tumors, Positron emission tomography, Progression-free survival, Endoscopic ultrasonography
Abstract: Purpose. The CT scan is the best common screening test for pancreatic cancer recurrence after surgery. The goal of our meta-analysis was to assess the diagnostic accuracy of 18F-FDG PET/CT for pancreatic cancer recurrence. Methods. We examined PubMed and Embase for suitable papers between 2009 and 2022. The researchers considered studies that looked at the diagnostic usefulness of 18F-FDG PET/CT in identifying local and/or distant disease recurrence throughout the follow-up following pancreatic cancer resection. The Quality Assessment of Diagnostic Performance Studies-2 (QUADAS-2) method was used to evaluate the quality of each study. For each of the publications included, two researchers extracted data independently. The extracted data included general data (authors, year of publication), literature characteristics (country, type of literature, and design of study), characteristics of the patient (patients' number, mean or median age, and treatment regimen), and technical aspects (scanner, injection activity, and image analysis). Results. The analysis includes 7 trials with a total of 263 patients. The sensitivity and specificity of 18F-FDG PET/CT in detecting recurrent pancreatic cancer following definitive treatment were 0.89 (95 percent CI: 0.83-0.93) and 0.88 (95 percent CI: 0.72-0.96), respectively, according to the pooled estimates. PET/CT performed well in the diagnosis of recurrent pancreatic cancer, with an AUC of 0.94. (0.91-0.95). Conclusions. 18F-FDG PET-CT was found to be a reliable detection method in recurrent pancreatic tumor. [ABSTRACT FROM AUTHOR]
Copyright of Applied Bionics & Biomechanics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Label: Title
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  Data: The Diagnostic Performance of 18F-FDG PET/CT in Recurrent Pancreatic Cancer: A Systematic Review and Meta-analysis.
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  Data: <searchLink fieldCode="AR" term="%22A%2C+Gu%22">A, Gu</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Shan%2C+Yuezhan%22">Shan, Yuezhan</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Huo%2C+Huasong%22">Huo, Huasong</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ding%2C+Chao%22">Ding, Chao</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sun%2C+Caixia%22">Sun, Caixia</searchLink><relatesTo>1</relatesTo> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Applied+Bionics+%26+Biomechanics%22">Applied Bionics & Biomechanics</searchLink>. 6/15/2022, p1-7. 7p.
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  Data: <searchLink fieldCode="DE" term="%22Pancreatic+cancer%22">Pancreatic cancer</searchLink><br /><searchLink fieldCode="DE" term="%22Fluorodeoxyglucose+F18%22">Fluorodeoxyglucose F18</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer+relapse%22">Cancer relapse</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer+diagnosis%22">Cancer diagnosis</searchLink><br /><searchLink fieldCode="DE" term="%22Pancreatic+tumors%22">Pancreatic tumors</searchLink><br /><searchLink fieldCode="DE" term="%22Positron+emission+tomography%22">Positron emission tomography</searchLink><br /><searchLink fieldCode="DE" term="%22Progression-free+survival%22">Progression-free survival</searchLink><br /><searchLink fieldCode="DE" term="%22Endoscopic+ultrasonography%22">Endoscopic ultrasonography</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Purpose. The CT scan is the best common screening test for pancreatic cancer recurrence after surgery. The goal of our meta-analysis was to assess the diagnostic accuracy of 18F-FDG PET/CT for pancreatic cancer recurrence. Methods. We examined PubMed and Embase for suitable papers between 2009 and 2022. The researchers considered studies that looked at the diagnostic usefulness of 18F-FDG PET/CT in identifying local and/or distant disease recurrence throughout the follow-up following pancreatic cancer resection. The Quality Assessment of Diagnostic Performance Studies-2 (QUADAS-2) method was used to evaluate the quality of each study. For each of the publications included, two researchers extracted data independently. The extracted data included general data (authors, year of publication), literature characteristics (country, type of literature, and design of study), characteristics of the patient (patients' number, mean or median age, and treatment regimen), and technical aspects (scanner, injection activity, and image analysis). Results. The analysis includes 7 trials with a total of 263 patients. The sensitivity and specificity of 18F-FDG PET/CT in detecting recurrent pancreatic cancer following definitive treatment were 0.89 (95 percent CI: 0.83-0.93) and 0.88 (95 percent CI: 0.72-0.96), respectively, according to the pooled estimates. PET/CT performed well in the diagnosis of recurrent pancreatic cancer, with an AUC of 0.94. (0.91-0.95). Conclusions. 18F-FDG PET-CT was found to be a reliable detection method in recurrent pancreatic tumor. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Applied Bionics & Biomechanics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1155/2022/3655225
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      – Code: eng
        Text: English
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        PageCount: 7
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      – SubjectFull: Pancreatic cancer
        Type: general
      – SubjectFull: Fluorodeoxyglucose F18
        Type: general
      – SubjectFull: Cancer relapse
        Type: general
      – SubjectFull: Cancer diagnosis
        Type: general
      – SubjectFull: Pancreatic tumors
        Type: general
      – SubjectFull: Positron emission tomography
        Type: general
      – SubjectFull: Progression-free survival
        Type: general
      – SubjectFull: Endoscopic ultrasonography
        Type: general
    Titles:
      – TitleFull: The Diagnostic Performance of 18F-FDG PET/CT in Recurrent Pancreatic Cancer: A Systematic Review and Meta-analysis.
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            NameFull: A, Gu
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            – D: 15
              M: 06
              Text: 6/15/2022
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              Y: 2022
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