Bio-Inspired Surface Modification of Magnetite Nanoparticles with Dopamine Conjugates.
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| Title: | Bio-Inspired Surface Modification of Magnetite Nanoparticles with Dopamine Conjugates. |
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| Authors: | Volov, Alexander1 (AUTHOR) volovalexander@gmail.com, Shkodenko, Liubov2 (AUTHOR) shkodenko@scamt-itmo.ru, Koshel, Elena2 (AUTHOR) koshel@scamt-itmo.ru, Drozdov, Andrey S.3 (AUTHOR) drozdov.science@gmail.com |
| Source: | Nanomaterials (2079-4991). Jul2022, Vol. 12 Issue 13, p2230-N.PAG. 13p. |
| Subjects: | Dopamine, Materials science, Nanoparticles, Magnetite, Amino group, Functional groups |
| Abstract: | Organically-coated nanomaterials are intensively studied and find numerous applications in a wide range of areas from optics to biomedicine. One of the recent trends in material science is the application of bio-mimetic polydopamine coatings that can be produced on a variety of substrates in a cost-efficient way under mild conditions. Such coatings not only modify the biocompatibility of the material but also add functional amino groups to the surface that can be further modified by classic conjugation techniques. Here we show an alternative strategy for substrates modification using dopamine conjugates instead of native dopamine. Compared to the classic scheme, the proposed strategy allows separation of the "organic" and "colloidal" stages, and simplified identification and purification steps. Modification with pre-modified dopamine made it possible to achieve high loading capacities with active components up to 10.5% wt. A series of organo-inorganic hybrids were synthesized and their bioactivity was analyzed. [ABSTRACT FROM AUTHOR] |
| Copyright of Nanomaterials (2079-4991) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Header | DbId: egs DbLabel: Engineering Source An: 157994701 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Bio-Inspired Surface Modification of Magnetite Nanoparticles with Dopamine Conjugates. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Volov%2C+Alexander%22">Volov, Alexander</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> volovalexander@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Shkodenko%2C+Liubov%22">Shkodenko, Liubov</searchLink><relatesTo>2</relatesTo> (AUTHOR)<i> shkodenko@scamt-itmo.ru</i><br /><searchLink fieldCode="AR" term="%22Koshel%2C+Elena%22">Koshel, Elena</searchLink><relatesTo>2</relatesTo> (AUTHOR)<i> koshel@scamt-itmo.ru</i><br /><searchLink fieldCode="AR" term="%22Drozdov%2C+Andrey+S%2E%22">Drozdov, Andrey S.</searchLink><relatesTo>3</relatesTo> (AUTHOR)<i> drozdov.science@gmail.com</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Nanomaterials+%282079-4991%29%22">Nanomaterials (2079-4991)</searchLink>. Jul2022, Vol. 12 Issue 13, p2230-N.PAG. 13p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Dopamine%22">Dopamine</searchLink><br /><searchLink fieldCode="DE" term="%22Materials+science%22">Materials science</searchLink><br /><searchLink fieldCode="DE" term="%22Nanoparticles%22">Nanoparticles</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetite%22">Magnetite</searchLink><br /><searchLink fieldCode="DE" term="%22Amino+group%22">Amino group</searchLink><br /><searchLink fieldCode="DE" term="%22Functional+groups%22">Functional groups</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Organically-coated nanomaterials are intensively studied and find numerous applications in a wide range of areas from optics to biomedicine. One of the recent trends in material science is the application of bio-mimetic polydopamine coatings that can be produced on a variety of substrates in a cost-efficient way under mild conditions. Such coatings not only modify the biocompatibility of the material but also add functional amino groups to the surface that can be further modified by classic conjugation techniques. Here we show an alternative strategy for substrates modification using dopamine conjugates instead of native dopamine. Compared to the classic scheme, the proposed strategy allows separation of the "organic" and "colloidal" stages, and simplified identification and purification steps. Modification with pre-modified dopamine made it possible to achieve high loading capacities with active components up to 10.5% wt. A series of organo-inorganic hybrids were synthesized and their bioactivity was analyzed. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Nanomaterials (2079-4991) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3390/nano12132230 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 13 StartPage: 2230 Subjects: – SubjectFull: Dopamine Type: general – SubjectFull: Materials science Type: general – SubjectFull: Nanoparticles Type: general – SubjectFull: Magnetite Type: general – SubjectFull: Amino group Type: general – SubjectFull: Functional groups Type: general Titles: – TitleFull: Bio-Inspired Surface Modification of Magnetite Nanoparticles with Dopamine Conjugates. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Volov, Alexander – PersonEntity: Name: NameFull: Shkodenko, Liubov – PersonEntity: Name: NameFull: Koshel, Elena – PersonEntity: Name: NameFull: Drozdov, Andrey S. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: Jul2022 Type: published Y: 2022 Identifiers: – Type: issn-print Value: 20794991 Numbering: – Type: volume Value: 12 – Type: issue Value: 13 Titles: – TitleFull: Nanomaterials (2079-4991) Type: main |
| ResultId | 1 |
