View in EDS

Optimization of Triterpenoid Extracted from Vietnamese Ganoderma lucidum via Supercritical Extraction Method and Biological Tests.

Saved in:
Bibliographic Details
Title: Optimization of Triterpenoid Extracted from Vietnamese Ganoderma lucidum via Supercritical Extraction Method and Biological Tests.
Authors: Dat, Tran Do1,2,3 (AUTHOR), Viet, Nguyen Duc1,2,3 (AUTHOR), Thanh, Vuong Hoai1,2,3 (AUTHOR), Nhi, Ho Nguyen Dieu1,2,3 (AUTHOR), Linh, Ngo Thi Thuy1,2,3 (AUTHOR), Ngan, Nguyen Thi Kim1,2,3 (AUTHOR), Nam, Hoang Minh1,2,3 (AUTHOR), Thanh Phong, Mai1,2,3 (AUTHOR), Hieu, Nguyen Huu1,2,3 (AUTHOR) nhhieubk@hcmut.edu.vn
Source: Separation Science & Technology. 2022, Vol. 57 Issue 14, p2211-2226. 16p.
Subjects: Ganoderma lucidum, Gas chromatography/Mass spectrometry (GC-MS), High performance liquid chromatography, Scanning electron microscopy, Test methods, Ethanol
Abstract: Herein, supercritical CO2 (SC–CO2) technique has been utilized to extract triterpenoid from Vietnamese Ganoderma lucidum (G. lucidum). Box–Behnken design was utilized to study the simultaneous effects between factors on triterpenoid content including extraction pressure, extraction time, and extraction temperature. Triterpenoid content was analyzed by using reversed-phase high-performance liquid chromatography with a diode array detector, using Pursuit XRs C18 reversed-phase column, the highest triterpenoid content was quantitatively analyzed for 2.735 ± 0.007 mg/g dry weight of material under optimal extraction conditions. Gas chromatography-mass spectrometry analysis revealed the presence of various compounds such as fatty acids and squalene in the ethanol extract of G. lucidum. Also, scanning electron microscopy images were used to evaluate material surfaces before and after extraction, thus proving the proposed mechanism of the extraction process by SC-CO2. The presence of triterpenoid and its derivatives were validated by the result of Fourier transform infrared spectra. SFE-CO2 extract has strong antioxidant, antibacterial and anti-cancer properties. As a result, SC–CO2 may be considered as a viable technique for triterpenoid extraction from G. lucidum. [ABSTRACT FROM AUTHOR]
Copyright of Separation Science & Technology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 158110142
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Optimization of Triterpenoid Extracted from Vietnamese Ganoderma lucidum via Supercritical Extraction Method and Biological Tests.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Dat%2C+Tran+Do%22">Dat, Tran Do</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Viet%2C+Nguyen+Duc%22">Viet, Nguyen Duc</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Thanh%2C+Vuong+Hoai%22">Thanh, Vuong Hoai</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nhi%2C+Ho+Nguyen+Dieu%22">Nhi, Ho Nguyen Dieu</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Linh%2C+Ngo+Thi+Thuy%22">Linh, Ngo Thi Thuy</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ngan%2C+Nguyen+Thi+Kim%22">Ngan, Nguyen Thi Kim</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nam%2C+Hoang+Minh%22">Nam, Hoang Minh</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Thanh+Phong%2C+Mai%22">Thanh Phong, Mai</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hieu%2C+Nguyen+Huu%22">Hieu, Nguyen Huu</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<i> nhhieubk@hcmut.edu.vn</i>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Separation+Science+%26+Technology%22">Separation Science & Technology</searchLink>. 2022, Vol. 57 Issue 14, p2211-2226. 16p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Ganoderma+lucidum%22">Ganoderma lucidum</searchLink><br /><searchLink fieldCode="DE" term="%22Gas+chromatography%2FMass+spectrometry+%28GC-MS%29%22">Gas chromatography/Mass spectrometry (GC-MS)</searchLink><br /><searchLink fieldCode="DE" term="%22High+performance+liquid+chromatography%22">High performance liquid chromatography</searchLink><br /><searchLink fieldCode="DE" term="%22Scanning+electron+microscopy%22">Scanning electron microscopy</searchLink><br /><searchLink fieldCode="DE" term="%22Test+methods%22">Test methods</searchLink><br /><searchLink fieldCode="DE" term="%22Ethanol%22">Ethanol</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Herein, supercritical CO2 (SC–CO2) technique has been utilized to extract triterpenoid from Vietnamese Ganoderma lucidum (G. lucidum). Box–Behnken design was utilized to study the simultaneous effects between factors on triterpenoid content including extraction pressure, extraction time, and extraction temperature. Triterpenoid content was analyzed by using reversed-phase high-performance liquid chromatography with a diode array detector, using Pursuit XRs C18 reversed-phase column, the highest triterpenoid content was quantitatively analyzed for 2.735 ± 0.007 mg/g dry weight of material under optimal extraction conditions. Gas chromatography-mass spectrometry analysis revealed the presence of various compounds such as fatty acids and squalene in the ethanol extract of G. lucidum. Also, scanning electron microscopy images were used to evaluate material surfaces before and after extraction, thus proving the proposed mechanism of the extraction process by SC-CO2. The presence of triterpenoid and its derivatives were validated by the result of Fourier transform infrared spectra. SFE-CO2 extract has strong antioxidant, antibacterial and anti-cancer properties. As a result, SC–CO2 may be considered as a viable technique for triterpenoid extraction from G. lucidum. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Separation Science & Technology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=158110142
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/01496395.2022.2032750
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 16
        StartPage: 2211
    Subjects:
      – SubjectFull: Ganoderma lucidum
        Type: general
      – SubjectFull: Gas chromatography/Mass spectrometry (GC-MS)
        Type: general
      – SubjectFull: High performance liquid chromatography
        Type: general
      – SubjectFull: Scanning electron microscopy
        Type: general
      – SubjectFull: Test methods
        Type: general
      – SubjectFull: Ethanol
        Type: general
    Titles:
      – TitleFull: Optimization of Triterpenoid Extracted from Vietnamese Ganoderma lucidum via Supercritical Extraction Method and Biological Tests.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Dat, Tran Do
      – PersonEntity:
          Name:
            NameFull: Viet, Nguyen Duc
      – PersonEntity:
          Name:
            NameFull: Thanh, Vuong Hoai
      – PersonEntity:
          Name:
            NameFull: Nhi, Ho Nguyen Dieu
      – PersonEntity:
          Name:
            NameFull: Linh, Ngo Thi Thuy
      – PersonEntity:
          Name:
            NameFull: Ngan, Nguyen Thi Kim
      – PersonEntity:
          Name:
            NameFull: Nam, Hoang Minh
      – PersonEntity:
          Name:
            NameFull: Thanh Phong, Mai
      – PersonEntity:
          Name:
            NameFull: Hieu, Nguyen Huu
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 15
              M: 09
              Text: 2022
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-print
              Value: 01496395
          Numbering:
            – Type: volume
              Value: 57
            – Type: issue
              Value: 14
          Titles:
            – TitleFull: Separation Science & Technology
              Type: main
ResultId 1