Presentation of Chloromas in B-Mode Ultrasound and Contrast-Enhanced Ultrasound.

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Title: Presentation of Chloromas in B-Mode Ultrasound and Contrast-Enhanced Ultrasound.
Authors: Trenker, Corinna1 (AUTHOR) Trenker@med.uni-marburg.de, Görg, Christian2 (AUTHOR), Burchert, Andreas1 (AUTHOR), Michel, Christian1 (AUTHOR), Kipper, Katharina2 (AUTHOR), Westhoff, Christina Carolin3 (AUTHOR), Keber, Corinna Ulrike3 (AUTHOR), Safai Zadeh, Ehsan2 (AUTHOR) ehsan_sz@yahoo.de
Source: Ultrasound in Medicine & Biology. Sep2022, Vol. 48 Issue 9, p1933-1940. 8p.
Subjects: Myeloid sarcoma, Extramedullary diseases, Acute myeloid leukemia, Progenitor cells, Myeloid cells, Ultrasonic imaging, Myeloid leukemia, Differential diagnosis, Contrast media, Retrospective studies
Abstract: Chloromas, also referred to as myeloid sarcomas, describe rare extramedullary tumor aggregates of malignant myeloid progenitor cells. The aim of this study was investigate the diagnostic features and characteristics of chloromas using contrast-enhanced ultrasound (CEUS). Between July 2007 and April 2021, 15 patients with 20 myeloid neoplasms and suspected chloroma manifestations were examined using B-mode US (B-US) and CEUS. Clinical data and B-US (echogenicity, border, size) and CEUS (hyper-, iso-, hypo- or complex enhancement) characteristics were retrospectively analyzed. Absolute and relative frequencies were determined. In B-US, the chloromas were most frequently hypo-echoic (n = 15, 75%). In addition, a hyperechoic (n = 2, 10%) or echocomplex (n = 3, 15%) presentation was observed. On CEUS, 7 chloromas (35%) had an arterial hyperenhancement, 8 (40%) an iso-enhancement and 3 (15%) a complex enhancement. Two chloromas (10%) did not exhibit any enhancement. We describe for the first time CEUS and B-US patterns of chloromas. They are typically hypo-echoic on B-US and have a strong iso- or hyperenhancement on CEUS, which may help in the differential diagnosis of some unclear masses (e.g., hematoma, abscess) in patients with myeloid neoplasias. Nevertheless, histology is necessary for a reliable diagnosis. [ABSTRACT FROM AUTHOR]
Copyright of Ultrasound in Medicine & Biology is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Label: Title
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  Data: Presentation of Chloromas in B-Mode Ultrasound and Contrast-Enhanced Ultrasound.
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  Label: Authors
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  Data: <searchLink fieldCode="AR" term="%22Trenker%2C+Corinna%22">Trenker, Corinna</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> Trenker@med.uni-marburg.de</i><br /><searchLink fieldCode="AR" term="%22Görg%2C+Christian%22">Görg, Christian</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Burchert%2C+Andreas%22">Burchert, Andreas</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Michel%2C+Christian%22">Michel, Christian</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kipper%2C+Katharina%22">Kipper, Katharina</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Westhoff%2C+Christina+Carolin%22">Westhoff, Christina Carolin</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Keber%2C+Corinna+Ulrike%22">Keber, Corinna Ulrike</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Safai+Zadeh%2C+Ehsan%22">Safai Zadeh, Ehsan</searchLink><relatesTo>2</relatesTo> (AUTHOR)<i> ehsan_sz@yahoo.de</i>
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  Data: <searchLink fieldCode="JN" term="%22Ultrasound+in+Medicine+%26+Biology%22">Ultrasound in Medicine & Biology</searchLink>. Sep2022, Vol. 48 Issue 9, p1933-1940. 8p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Myeloid+sarcoma%22">Myeloid sarcoma</searchLink><br /><searchLink fieldCode="DE" term="%22Extramedullary+diseases%22">Extramedullary diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Acute+myeloid+leukemia%22">Acute myeloid leukemia</searchLink><br /><searchLink fieldCode="DE" term="%22Progenitor+cells%22">Progenitor cells</searchLink><br /><searchLink fieldCode="DE" term="%22Myeloid+cells%22">Myeloid cells</searchLink><br /><searchLink fieldCode="DE" term="%22Ultrasonic+imaging%22">Ultrasonic imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Myeloid+leukemia%22">Myeloid leukemia</searchLink><br /><searchLink fieldCode="DE" term="%22Differential+diagnosis%22">Differential diagnosis</searchLink><br /><searchLink fieldCode="DE" term="%22Contrast+media%22">Contrast media</searchLink><br /><searchLink fieldCode="DE" term="%22Retrospective+studies%22">Retrospective studies</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Chloromas, also referred to as myeloid sarcomas, describe rare extramedullary tumor aggregates of malignant myeloid progenitor cells. The aim of this study was investigate the diagnostic features and characteristics of chloromas using contrast-enhanced ultrasound (CEUS). Between July 2007 and April 2021, 15 patients with 20 myeloid neoplasms and suspected chloroma manifestations were examined using B-mode US (B-US) and CEUS. Clinical data and B-US (echogenicity, border, size) and CEUS (hyper-, iso-, hypo- or complex enhancement) characteristics were retrospectively analyzed. Absolute and relative frequencies were determined. In B-US, the chloromas were most frequently hypo-echoic (n = 15, 75%). In addition, a hyperechoic (n = 2, 10%) or echocomplex (n = 3, 15%) presentation was observed. On CEUS, 7 chloromas (35%) had an arterial hyperenhancement, 8 (40%) an iso-enhancement and 3 (15%) a complex enhancement. Two chloromas (10%) did not exhibit any enhancement. We describe for the first time CEUS and B-US patterns of chloromas. They are typically hypo-echoic on B-US and have a strong iso- or hyperenhancement on CEUS, which may help in the differential diagnosis of some unclear masses (e.g., hematoma, abscess) in patients with myeloid neoplasias. Nevertheless, histology is necessary for a reliable diagnosis. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Ultrasound in Medicine & Biology is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.ultrasmedbio.2022.05.024
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 1933
    Subjects:
      – SubjectFull: Myeloid sarcoma
        Type: general
      – SubjectFull: Extramedullary diseases
        Type: general
      – SubjectFull: Acute myeloid leukemia
        Type: general
      – SubjectFull: Progenitor cells
        Type: general
      – SubjectFull: Myeloid cells
        Type: general
      – SubjectFull: Ultrasonic imaging
        Type: general
      – SubjectFull: Myeloid leukemia
        Type: general
      – SubjectFull: Differential diagnosis
        Type: general
      – SubjectFull: Contrast media
        Type: general
      – SubjectFull: Retrospective studies
        Type: general
    Titles:
      – TitleFull: Presentation of Chloromas in B-Mode Ultrasound and Contrast-Enhanced Ultrasound.
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            NameFull: Trenker, Corinna
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            NameFull: Görg, Christian
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            – D: 01
              M: 09
              Text: Sep2022
              Type: published
              Y: 2022
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              Value: 48
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