Presentation of Chloromas in B-Mode Ultrasound and Contrast-Enhanced Ultrasound.
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| Title: | Presentation of Chloromas in B-Mode Ultrasound and Contrast-Enhanced Ultrasound. |
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| Authors: | Trenker, Corinna1 (AUTHOR) Trenker@med.uni-marburg.de, Görg, Christian2 (AUTHOR), Burchert, Andreas1 (AUTHOR), Michel, Christian1 (AUTHOR), Kipper, Katharina2 (AUTHOR), Westhoff, Christina Carolin3 (AUTHOR), Keber, Corinna Ulrike3 (AUTHOR), Safai Zadeh, Ehsan2 (AUTHOR) ehsan_sz@yahoo.de |
| Source: | Ultrasound in Medicine & Biology. Sep2022, Vol. 48 Issue 9, p1933-1940. 8p. |
| Subjects: | Myeloid sarcoma, Extramedullary diseases, Acute myeloid leukemia, Progenitor cells, Myeloid cells, Ultrasonic imaging, Myeloid leukemia, Differential diagnosis, Contrast media, Retrospective studies |
| Abstract: | Chloromas, also referred to as myeloid sarcomas, describe rare extramedullary tumor aggregates of malignant myeloid progenitor cells. The aim of this study was investigate the diagnostic features and characteristics of chloromas using contrast-enhanced ultrasound (CEUS). Between July 2007 and April 2021, 15 patients with 20 myeloid neoplasms and suspected chloroma manifestations were examined using B-mode US (B-US) and CEUS. Clinical data and B-US (echogenicity, border, size) and CEUS (hyper-, iso-, hypo- or complex enhancement) characteristics were retrospectively analyzed. Absolute and relative frequencies were determined. In B-US, the chloromas were most frequently hypo-echoic (n = 15, 75%). In addition, a hyperechoic (n = 2, 10%) or echocomplex (n = 3, 15%) presentation was observed. On CEUS, 7 chloromas (35%) had an arterial hyperenhancement, 8 (40%) an iso-enhancement and 3 (15%) a complex enhancement. Two chloromas (10%) did not exhibit any enhancement. We describe for the first time CEUS and B-US patterns of chloromas. They are typically hypo-echoic on B-US and have a strong iso- or hyperenhancement on CEUS, which may help in the differential diagnosis of some unclear masses (e.g., hematoma, abscess) in patients with myeloid neoplasias. Nevertheless, histology is necessary for a reliable diagnosis. [ABSTRACT FROM AUTHOR] |
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| Database: | Engineering Source |
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