Localized Nanopore Fabrication via Controlled Breakdown.
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| Title: | Localized Nanopore Fabrication via Controlled Breakdown. |
|---|---|
| Authors: | Ying, Cuifeng1 (AUTHOR) cuifeng.ying@ntu.ac.uk, Ma, Tianji2 (AUTHOR) tianji.ma@csust.edu.cn, Xu, Lei1 (AUTHOR) mohsen.rahmani@ntu.ac.uk, Rahmani, Mohsen1 (AUTHOR) |
| Source: | Nanomaterials (2079-4991). Jul2022, Vol. 12 Issue 14, pN.PAG-N.PAG. 22p. |
| Subjects: | Field-effect devices, Field-effect transistors, Chemical labeling, Nanopores, Cannabidiol, Nucleic acids |
| Abstract: | Nanopore sensors provide a unique platform to detect individual nucleic acids, proteins, and other biomolecules without the need for fluorescent labeling or chemical modifications. Solid-state nanopores offer the potential to integrate nanopore sensing with other technologies such as field-effect transistors (FETs), optics, plasmonics, and microfluidics, thereby attracting attention to the development of commercial instruments for diagnostics and healthcare applications. Stable nanopores with ideal dimensions are particularly critical for nanopore sensors to be integrated into other sensing devices and provide a high signal-to-noise ratio. Nanopore fabrication, although having benefited largely from the development of sophisticated nanofabrication techniques, remains a challenge in terms of cost, time consumption and accessibility. One of the latest developed methods—controlled breakdown (CBD)—has made the nanopore technique broadly accessible, boosting the use of nanopore sensing in both fundamental research and biomedical applications. Many works have been developed to improve the efficiency and robustness of pore formation by CBD. However, nanopores formed by traditional CBD are randomly positioned in the membrane. To expand nanopore sensing to a wider biomedical application, controlling the localization of nanopores formed by CBD is essential. This article reviews the recent strategies to control the location of nanopores formed by CBD. We discuss the fundamental mechanism and the efforts of different approaches to confine the region of nanopore formation. [ABSTRACT FROM AUTHOR] |
| Copyright of Nanomaterials (2079-4991) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Header | DbId: egs DbLabel: Engineering Source An: 158299444 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Localized Nanopore Fabrication via Controlled Breakdown. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Ying%2C+Cuifeng%22">Ying, Cuifeng</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> cuifeng.ying@ntu.ac.uk</i><br /><searchLink fieldCode="AR" term="%22Ma%2C+Tianji%22">Ma, Tianji</searchLink><relatesTo>2</relatesTo> (AUTHOR)<i> tianji.ma@csust.edu.cn</i><br /><searchLink fieldCode="AR" term="%22Xu%2C+Lei%22">Xu, Lei</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> mohsen.rahmani@ntu.ac.uk</i><br /><searchLink fieldCode="AR" term="%22Rahmani%2C+Mohsen%22">Rahmani, Mohsen</searchLink><relatesTo>1</relatesTo> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Nanomaterials+%282079-4991%29%22">Nanomaterials (2079-4991)</searchLink>. Jul2022, Vol. 12 Issue 14, pN.PAG-N.PAG. 22p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Field-effect+devices%22">Field-effect devices</searchLink><br /><searchLink fieldCode="DE" term="%22Field-effect+transistors%22">Field-effect transistors</searchLink><br /><searchLink fieldCode="DE" term="%22Chemical+labeling%22">Chemical labeling</searchLink><br /><searchLink fieldCode="DE" term="%22Nanopores%22">Nanopores</searchLink><br /><searchLink fieldCode="DE" term="%22Cannabidiol%22">Cannabidiol</searchLink><br /><searchLink fieldCode="DE" term="%22Nucleic+acids%22">Nucleic acids</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Nanopore sensors provide a unique platform to detect individual nucleic acids, proteins, and other biomolecules without the need for fluorescent labeling or chemical modifications. Solid-state nanopores offer the potential to integrate nanopore sensing with other technologies such as field-effect transistors (FETs), optics, plasmonics, and microfluidics, thereby attracting attention to the development of commercial instruments for diagnostics and healthcare applications. Stable nanopores with ideal dimensions are particularly critical for nanopore sensors to be integrated into other sensing devices and provide a high signal-to-noise ratio. Nanopore fabrication, although having benefited largely from the development of sophisticated nanofabrication techniques, remains a challenge in terms of cost, time consumption and accessibility. One of the latest developed methods—controlled breakdown (CBD)—has made the nanopore technique broadly accessible, boosting the use of nanopore sensing in both fundamental research and biomedical applications. Many works have been developed to improve the efficiency and robustness of pore formation by CBD. However, nanopores formed by traditional CBD are randomly positioned in the membrane. To expand nanopore sensing to a wider biomedical application, controlling the localization of nanopores formed by CBD is essential. This article reviews the recent strategies to control the location of nanopores formed by CBD. We discuss the fundamental mechanism and the efforts of different approaches to confine the region of nanopore formation. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Nanomaterials (2079-4991) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3390/nano12142384 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 22 StartPage: N.PAG Subjects: – SubjectFull: Field-effect devices Type: general – SubjectFull: Field-effect transistors Type: general – SubjectFull: Chemical labeling Type: general – SubjectFull: Nanopores Type: general – SubjectFull: Cannabidiol Type: general – SubjectFull: Nucleic acids Type: general Titles: – TitleFull: Localized Nanopore Fabrication via Controlled Breakdown. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ying, Cuifeng – PersonEntity: Name: NameFull: Ma, Tianji – PersonEntity: Name: NameFull: Xu, Lei – PersonEntity: Name: NameFull: Rahmani, Mohsen IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 07 Text: Jul2022 Type: published Y: 2022 Identifiers: – Type: issn-print Value: 20794991 Numbering: – Type: volume Value: 12 – Type: issue Value: 14 Titles: – TitleFull: Nanomaterials (2079-4991) Type: main |
| ResultId | 1 |
