View in EDS

An evidence map of polychlorinated biphenyl exposure and health outcome studies among residents of the Akwesasne Mohawk Nation.

Saved in:
Bibliographic Details
Title: An evidence map of polychlorinated biphenyl exposure and health outcome studies among residents of the Akwesasne Mohawk Nation.
Authors: Weitekamp, Chelsea A.1 (AUTHOR), Shaffer, Rachel M.2 (AUTHOR), Chiang, Catheryne1 (AUTHOR), Lehmann, Geniece M.1 (AUTHOR) lehmann.geniece@epa.gov, Christensen, Krista2 (AUTHOR)
Source: Chemosphere. Nov2022, Vol. 306, pN.PAG-N.PAG. 1p.
Subjects: Polychlorinated biphenyls, Hazardous waste sites, Diphenyl, Human ecology, Detection limit, Sample size (Statistics)
Abstract: From the 1950s to the 1970s, three Superfund sites discharged polychlorinated biphenyl (PCB)-contaminated waste upstream of the Mohawk Nation at Akwesasne, resulting in PCB contamination of groundwater, soil, and sediment in the surrounding area. Given the persistence of PCBs in the environment and in human tissues, there are continued concerns regarding PCB exposures and the potential for adverse health effects in the community. We developed an evidence map of PCB research at Akwesasne in order to characterize the available data and to highlight potential research needs. Human health and exposure biomarker studies were identified from a literature search based on population, exposure, comparator, and outcome (PECO) criteria. Data extracted from references that met the inclusion criteria after full-text review included study characteristics (e.g., sample size, study design, sampling years), details on PCB measurements (e.g., analytical method, number of congeners analyzed, method detection limits), and results (e.g., PCB levels and summary of study conclusions). We identified 33 studies, conducted between 1986 and 2013, that examined PCB exposure characteristics and health effects in residents of the Akwesasne Mohawk Nation. Organizing this literature into an evidence map including information on study cohort, congener groupings, exposure biomarker characteristics, and health effects allowed us to identify research gaps and to suggest future research priorities for the community. We identified current PCB exposure levels and PCB source characterization as major uncertainties, both of which could be addressed by new studies of PCB concentrations in environmental media. [Display omitted] • This evidence map describes human health research on PCBs at Akwesasne. • We identified 33 studies of PCB health effects and/or exposure characteristics. • We organized studies by cohort, PCB exposure measures, and health effects. • Major uncertainties are current PCB exposure levels and source characterization. [ABSTRACT FROM AUTHOR]
Copyright of Chemosphere is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 158746814
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: An evidence map of polychlorinated biphenyl exposure and health outcome studies among residents of the Akwesasne Mohawk Nation.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Weitekamp%2C+Chelsea+A%2E%22">Weitekamp, Chelsea A.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Shaffer%2C+Rachel+M%2E%22">Shaffer, Rachel M.</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chiang%2C+Catheryne%22">Chiang, Catheryne</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lehmann%2C+Geniece+M%2E%22">Lehmann, Geniece M.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> lehmann.geniece@epa.gov</i><br /><searchLink fieldCode="AR" term="%22Christensen%2C+Krista%22">Christensen, Krista</searchLink><relatesTo>2</relatesTo> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Chemosphere%22">Chemosphere</searchLink>. Nov2022, Vol. 306, pN.PAG-N.PAG. 1p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Polychlorinated+biphenyls%22">Polychlorinated biphenyls</searchLink><br /><searchLink fieldCode="DE" term="%22Hazardous+waste+sites%22">Hazardous waste sites</searchLink><br /><searchLink fieldCode="DE" term="%22Diphenyl%22">Diphenyl</searchLink><br /><searchLink fieldCode="DE" term="%22Human+ecology%22">Human ecology</searchLink><br /><searchLink fieldCode="DE" term="%22Detection+limit%22">Detection limit</searchLink><br /><searchLink fieldCode="DE" term="%22Sample+size+%28Statistics%29%22">Sample size (Statistics)</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: From the 1950s to the 1970s, three Superfund sites discharged polychlorinated biphenyl (PCB)-contaminated waste upstream of the Mohawk Nation at Akwesasne, resulting in PCB contamination of groundwater, soil, and sediment in the surrounding area. Given the persistence of PCBs in the environment and in human tissues, there are continued concerns regarding PCB exposures and the potential for adverse health effects in the community. We developed an evidence map of PCB research at Akwesasne in order to characterize the available data and to highlight potential research needs. Human health and exposure biomarker studies were identified from a literature search based on population, exposure, comparator, and outcome (PECO) criteria. Data extracted from references that met the inclusion criteria after full-text review included study characteristics (e.g., sample size, study design, sampling years), details on PCB measurements (e.g., analytical method, number of congeners analyzed, method detection limits), and results (e.g., PCB levels and summary of study conclusions). We identified 33 studies, conducted between 1986 and 2013, that examined PCB exposure characteristics and health effects in residents of the Akwesasne Mohawk Nation. Organizing this literature into an evidence map including information on study cohort, congener groupings, exposure biomarker characteristics, and health effects allowed us to identify research gaps and to suggest future research priorities for the community. We identified current PCB exposure levels and PCB source characterization as major uncertainties, both of which could be addressed by new studies of PCB concentrations in environmental media. [Display omitted] • This evidence map describes human health research on PCBs at Akwesasne. • We identified 33 studies of PCB health effects and/or exposure characteristics. • We organized studies by cohort, PCB exposure measures, and health effects. • Major uncertainties are current PCB exposure levels and source characterization. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Chemosphere is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=158746814
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.chemosphere.2022.135454
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 1
        StartPage: N.PAG
    Subjects:
      – SubjectFull: Polychlorinated biphenyls
        Type: general
      – SubjectFull: Hazardous waste sites
        Type: general
      – SubjectFull: Diphenyl
        Type: general
      – SubjectFull: Human ecology
        Type: general
      – SubjectFull: Detection limit
        Type: general
      – SubjectFull: Sample size (Statistics)
        Type: general
    Titles:
      – TitleFull: An evidence map of polychlorinated biphenyl exposure and health outcome studies among residents of the Akwesasne Mohawk Nation.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Weitekamp, Chelsea A.
      – PersonEntity:
          Name:
            NameFull: Shaffer, Rachel M.
      – PersonEntity:
          Name:
            NameFull: Chiang, Catheryne
      – PersonEntity:
          Name:
            NameFull: Lehmann, Geniece M.
      – PersonEntity:
          Name:
            NameFull: Christensen, Krista
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 11
              Text: Nov2022
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-print
              Value: 00456535
          Numbering:
            – Type: volume
              Value: 306
          Titles:
            – TitleFull: Chemosphere
              Type: main
ResultId 1