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Current Research on Zinc Oxide Nanoparticles: Synthesis, Characterization, and Biomedical Applications.

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Title: Current Research on Zinc Oxide Nanoparticles: Synthesis, Characterization, and Biomedical Applications.
Authors: Mandal, Ashok Kumar1 (AUTHOR), Katuwal, Saurav2 (AUTHOR), Tettey, Felix3 (AUTHOR), Gupta, Aakash4 (AUTHOR), Bhattarai, Salyan5 (AUTHOR), Jaisi, Shankar2 (AUTHOR), Bhandari, Devi Prasad1,2 (AUTHOR), Shah, Ajay Kumar6 (AUTHOR), Bhattarai, Narayan3 (AUTHOR) nbhattar@ncat.edu, Parajuli, Niranjan2 (AUTHOR) nbhattar@ncat.edu
Source: Nanomaterials (2079-4991). Sep2022, Vol. 12 Issue 17, p3066. 31p.
Subjects: Zinc oxide synthesis, Metal nanoparticles, Zinc oxide, Phytotherapy, Extraction techniques, Surface morphology
Abstract: Zinc oxide nanoparticles (ZnO-NPs) have piqued the curiosity of researchers all over the world due to their extensive biological activity. They are less toxic and biodegradable with the capacity to greatly boost pharmacophore bioactivity. ZnO-NPs are the most extensively used metal oxide nanoparticles in electronic and optoelectronics because of their distinctive optical and chemical properties which can be readily modified by altering the morphology and the wide bandgap. The biosynthesis of nanoparticles using extracts of therapeutic plants, fungi, bacteria, algae, etc., improves their stability and biocompatibility in many biological settings, and its biofabrication alters its physiochemical behavior, contributing to biological potency. As such, ZnO-NPs can be used as an effective nanocarrier for conventional drugs due to their cost-effectiveness and benefits of being biodegradable and biocompatible. This article covers a comprehensive review of different synthesis approaches of ZnO-NPs including physical, chemical, biochemical, and green synthesis techniques, and also emphasizes their biopotency through antibacterial, antifungal, anticancer, anti-inflammatory, antidiabetic, antioxidant, antiviral, wound healing, and cardioprotective activity. Green synthesis from plants, bacteria, and fungus is given special attention, with a particular emphasis on extraction techniques, precursors used for the synthesis and reaction conditions, characterization techniques, and surface morphology of the particles. [ABSTRACT FROM AUTHOR]
Copyright of Nanomaterials (2079-4991) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Current Research on Zinc Oxide Nanoparticles: Synthesis, Characterization, and Biomedical Applications.
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  Data: <searchLink fieldCode="DE" term="%22Zinc+oxide+synthesis%22">Zinc oxide synthesis</searchLink><br /><searchLink fieldCode="DE" term="%22Metal+nanoparticles%22">Metal nanoparticles</searchLink><br /><searchLink fieldCode="DE" term="%22Zinc+oxide%22">Zinc oxide</searchLink><br /><searchLink fieldCode="DE" term="%22Phytotherapy%22">Phytotherapy</searchLink><br /><searchLink fieldCode="DE" term="%22Extraction+techniques%22">Extraction techniques</searchLink><br /><searchLink fieldCode="DE" term="%22Surface+morphology%22">Surface morphology</searchLink>
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  Data: Zinc oxide nanoparticles (ZnO-NPs) have piqued the curiosity of researchers all over the world due to their extensive biological activity. They are less toxic and biodegradable with the capacity to greatly boost pharmacophore bioactivity. ZnO-NPs are the most extensively used metal oxide nanoparticles in electronic and optoelectronics because of their distinctive optical and chemical properties which can be readily modified by altering the morphology and the wide bandgap. The biosynthesis of nanoparticles using extracts of therapeutic plants, fungi, bacteria, algae, etc., improves their stability and biocompatibility in many biological settings, and its biofabrication alters its physiochemical behavior, contributing to biological potency. As such, ZnO-NPs can be used as an effective nanocarrier for conventional drugs due to their cost-effectiveness and benefits of being biodegradable and biocompatible. This article covers a comprehensive review of different synthesis approaches of ZnO-NPs including physical, chemical, biochemical, and green synthesis techniques, and also emphasizes their biopotency through antibacterial, antifungal, anticancer, anti-inflammatory, antidiabetic, antioxidant, antiviral, wound healing, and cardioprotective activity. Green synthesis from plants, bacteria, and fungus is given special attention, with a particular emphasis on extraction techniques, precursors used for the synthesis and reaction conditions, characterization techniques, and surface morphology of the particles. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of Nanomaterials (2079-4991) is the property of MDPI and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.3390/nano12173066
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        Text: English
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      – SubjectFull: Zinc oxide synthesis
        Type: general
      – SubjectFull: Metal nanoparticles
        Type: general
      – SubjectFull: Zinc oxide
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      – SubjectFull: Phytotherapy
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      – SubjectFull: Extraction techniques
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      – SubjectFull: Surface morphology
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              Text: Sep2022
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