Bridging environmental and biological monitoring: Constructing platform for hexavalent chromium detection and cancer-cells screening based on red fluorescent carbonized polymer dots.
Saved in:
| Title: | Bridging environmental and biological monitoring: Constructing platform for hexavalent chromium detection and cancer-cells screening based on red fluorescent carbonized polymer dots. |
|---|---|
| Authors: | Wang, Xin1 (AUTHOR), Hu, Jinshuang1 (AUTHOR), Yao, Boxuan1 (AUTHOR), Wei, Hua1 (AUTHOR), Zhang, Caiyun1 (AUTHOR), Zhou, Jiarui1 (AUTHOR), Liu, Jian2 (AUTHOR), Yang, Shenghong1 (AUTHOR) yangsh@qlu.edu.cn |
| Source: | Chemical Engineering Journal. Jan2023:Part 1, Vol. 451, pN.PAG-N.PAG. 1p. |
| Subjects: | Fluorescent polymers, Hexavalent chromium, Biological monitoring, Environmental monitoring, Cell imaging, Image analysis |
| Abstract: | • Rational designed R-PDs was obtained through facile hydrothermal method. • A high-throughput scanometric analysis platform of Cr(VI) was constructed. • Visual imaging analysis of Cr(Ⅵ) in living cells and in vivo was realized. • R-PDs was successfully used for distinguishing cancerous and normal cells. Intensive research on biocompatible carbon-based fluorescent nanomaterials provides a brand-new platform for environmental and biological monitoring, but its applicability is limited by the single signal response, unfriendly synthesis route, or rare red fluorescence performance. In this study, we designed and prepared a new type of high-efficiency red fluorescent carbonized polymer dots (R-PDs) through rationally preferred raw materials. The proposed R-PDs with colorimetric and fluorescent dual-signal response to hexavalent chromium (Cr(VI)) can be obtained easily by hydrothermal treatment of o-hydroxybenzoic acid and p-phenylenediamine. A high-throughput smartphone-mediated scanometric analysis platform was constructed based on sensitive gray change, which was further applied for the rapid, simple, and low-cost detection of Cr(VI) in real environmental water. The fluorescent analysis mode exhibits high sensitivity with the limit of detection 20 nM, thereby realizing the Cr(VI) imaging in living cells and aquatic species. More importantly, R-PDs exhibited excellent nucleolus targeting capacity by virtue of their inherent high nitrogen content, thus successfully screening normal and cancerous cells. Encouraged by the simplicity of synthesis and availability of constructed analysis platform, the proposed R-PDs has great potential applications in environmental monitoring, biosensing and biomedical. [ABSTRACT FROM AUTHOR] |
| Copyright of Chemical Engineering Journal is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: egs DbLabel: Engineering Source An: 159564776 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Bridging environmental and biological monitoring: Constructing platform for hexavalent chromium detection and cancer-cells screening based on red fluorescent carbonized polymer dots. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Wang%2C+Xin%22">Wang, Xin</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hu%2C+Jinshuang%22">Hu, Jinshuang</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yao%2C+Boxuan%22">Yao, Boxuan</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wei%2C+Hua%22">Wei, Hua</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhang%2C+Caiyun%22">Zhang, Caiyun</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhou%2C+Jiarui%22">Zhou, Jiarui</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liu%2C+Jian%22">Liu, Jian</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yang%2C+Shenghong%22">Yang, Shenghong</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> yangsh@qlu.edu.cn</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Chemical+Engineering+Journal%22">Chemical Engineering Journal</searchLink>. Jan2023:Part 1, Vol. 451, pN.PAG-N.PAG. 1p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Fluorescent+polymers%22">Fluorescent polymers</searchLink><br /><searchLink fieldCode="DE" term="%22Hexavalent+chromium%22">Hexavalent chromium</searchLink><br /><searchLink fieldCode="DE" term="%22Biological+monitoring%22">Biological monitoring</searchLink><br /><searchLink fieldCode="DE" term="%22Environmental+monitoring%22">Environmental monitoring</searchLink><br /><searchLink fieldCode="DE" term="%22Cell+imaging%22">Cell imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Image+analysis%22">Image analysis</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: • Rational designed R-PDs was obtained through facile hydrothermal method. • A high-throughput scanometric analysis platform of Cr(VI) was constructed. • Visual imaging analysis of Cr(Ⅵ) in living cells and in vivo was realized. • R-PDs was successfully used for distinguishing cancerous and normal cells. Intensive research on biocompatible carbon-based fluorescent nanomaterials provides a brand-new platform for environmental and biological monitoring, but its applicability is limited by the single signal response, unfriendly synthesis route, or rare red fluorescence performance. In this study, we designed and prepared a new type of high-efficiency red fluorescent carbonized polymer dots (R-PDs) through rationally preferred raw materials. The proposed R-PDs with colorimetric and fluorescent dual-signal response to hexavalent chromium (Cr(VI)) can be obtained easily by hydrothermal treatment of o-hydroxybenzoic acid and p-phenylenediamine. A high-throughput smartphone-mediated scanometric analysis platform was constructed based on sensitive gray change, which was further applied for the rapid, simple, and low-cost detection of Cr(VI) in real environmental water. The fluorescent analysis mode exhibits high sensitivity with the limit of detection 20 nM, thereby realizing the Cr(VI) imaging in living cells and aquatic species. More importantly, R-PDs exhibited excellent nucleolus targeting capacity by virtue of their inherent high nitrogen content, thus successfully screening normal and cancerous cells. Encouraged by the simplicity of synthesis and availability of constructed analysis platform, the proposed R-PDs has great potential applications in environmental monitoring, biosensing and biomedical. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Chemical Engineering Journal is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=159564776 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.cej.2022.138524 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 1 StartPage: N.PAG Subjects: – SubjectFull: Fluorescent polymers Type: general – SubjectFull: Hexavalent chromium Type: general – SubjectFull: Biological monitoring Type: general – SubjectFull: Environmental monitoring Type: general – SubjectFull: Cell imaging Type: general – SubjectFull: Image analysis Type: general Titles: – TitleFull: Bridging environmental and biological monitoring: Constructing platform for hexavalent chromium detection and cancer-cells screening based on red fluorescent carbonized polymer dots. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wang, Xin – PersonEntity: Name: NameFull: Hu, Jinshuang – PersonEntity: Name: NameFull: Yao, Boxuan – PersonEntity: Name: NameFull: Wei, Hua – PersonEntity: Name: NameFull: Zhang, Caiyun – PersonEntity: Name: NameFull: Zhou, Jiarui – PersonEntity: Name: NameFull: Liu, Jian – PersonEntity: Name: NameFull: Yang, Shenghong IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan2023:Part 1 Type: published Y: 2023 Identifiers: – Type: issn-print Value: 13858947 Numbering: – Type: volume Value: 451 Titles: – TitleFull: Chemical Engineering Journal Type: main |
| ResultId | 1 |
