View in EDS HTML Full Text PDF Full Text

Pectus excavatum in motion: dynamic evaluation using real-time MRI.

Saved in:
Bibliographic Details
Title: Pectus excavatum in motion: dynamic evaluation using real-time MRI.
Authors: Gräfe, Daniel1 daniel.graefe@medizin.uni-leipzig.de, Lacher, Martin2, Martynov, Illya2, Hirsch, Franz Wolfgang1, Voit, Dirk3, Frahm, Jens3, Busse, Harald4, Sesia, Sergio Bruno5, Krämer, Sebastian6, Zimmermann, Peter2
Source: European Radiology. Mar2023, Vol. 33 Issue 3, p2128-2135. 8p. 1 Color Photograph, 4 Graphs.
Subjects: Pectus excavatum, Respiration, Magnetic resonance imaging, Rib abnormalities, Sternum abnormalities
Abstract: Objectives: The breathing phase for the determination of thoracic indices in patients with pectus excavatum is not standardized. The aim of this study was to identify the best period for reliable assessments of morphologic indices by dynamic observations of the chest wall using real-time MRI. Methods: In this prospective study, patients with pectus excavatum underwent morphologic evaluation by real-time MRI at 3 T between January 2020 and June 2021. The Haller index (HI), correction index (CI), modified asymmetry index (AI), and modified eccentricity index (EI) were determined during free, quiet, and forced breathing respectively. Breathing-related differences in the thoracic indices were analyzed with the Wilcoxon signed-rank test. Motion of the anterior chest wall was analyzed as well. Results: A total of 56 patients (11 females and 45 males, median age 15.4 years, interquartile range 14.3–16.9) were included. In quiet expiration, the median HI in the cohort equaled 5.7 (4.5–7.2). The median absolute differences (Δ) in the thoracic indices between peak inspiration and peak expiration were ΔHI = 1.1 (0.7–1.6, p <.001), ΔCI = 4.8% (1.3–7.5%, p <.001), ΔAI = 3.0% (1.0–5.0%, p <.001), and ΔEI = 8.0% (3.0–14.0%, p <.05). The indices varied significantly during different inspiratory phases, but not during expiration (p >.05 each). Furthermore, the dynamic evaluation revealed three distinctive movement patterns of the funnel chest. Conclusions: Real-time MRI reveals patterns of chest wall motion and indicate that thoracic indices of pectus excavatum should be assessed in the end-expiratory phase of quiet expiration. Key Points: • The thoracic indices in patients with pectus excavatum depend on the breathing phase. • Quiet expiration represents the best breathing phase for determining thoracic indices. • Real-time MRI can identify different chest wall motion patterns in pectus excavatum. [ABSTRACT FROM AUTHOR]
Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: egs
DbLabel: Engineering Source
An: 161963610
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Pectus excavatum in motion: dynamic evaluation using real-time MRI.
– Name: Author
  Label: Authors
  Group: Au
  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Gr&#228;fe%2C+Daniel%22&quot;&gt;Gr&#228;fe, Daniel&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;i&gt; daniel.graefe@medizin.uni-leipzig.de&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lacher%2C+Martin%22&quot;&gt;Lacher, Martin&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Martynov%2C+Illya%22&quot;&gt;Martynov, Illya&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Hirsch%2C+Franz+Wolfgang%22&quot;&gt;Hirsch, Franz Wolfgang&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Voit%2C+Dirk%22&quot;&gt;Voit, Dirk&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Frahm%2C+Jens%22&quot;&gt;Frahm, Jens&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Busse%2C+Harald%22&quot;&gt;Busse, Harald&lt;/searchLink&gt;&lt;relatesTo&gt;4&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Sesia%2C+Sergio+Bruno%22&quot;&gt;Sesia, Sergio Bruno&lt;/searchLink&gt;&lt;relatesTo&gt;5&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Kr&#228;mer%2C+Sebastian%22&quot;&gt;Kr&#228;mer, Sebastian&lt;/searchLink&gt;&lt;relatesTo&gt;6&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Zimmermann%2C+Peter%22&quot;&gt;Zimmermann, Peter&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;
– Name: TitleSource
  Label: Source
  Group: Src
  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22European+Radiology%22&quot;&gt;European Radiology&lt;/searchLink&gt;. Mar2023, Vol. 33 Issue 3, p2128-2135. 8p. 1 Color Photograph, 4 Graphs.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Pectus+excavatum%22&quot;&gt;Pectus excavatum&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Respiration%22&quot;&gt;Respiration&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Magnetic+resonance+imaging%22&quot;&gt;Magnetic resonance imaging&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Rib+abnormalities%22&quot;&gt;Rib abnormalities&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Sternum+abnormalities%22&quot;&gt;Sternum abnormalities&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objectives: The breathing phase for the determination of thoracic indices in patients with pectus excavatum is not standardized. The aim of this study was to identify the best period for reliable assessments of morphologic indices by dynamic observations of the chest wall using real-time MRI. Methods: In this prospective study, patients with pectus excavatum underwent morphologic evaluation by real-time MRI at 3 T between January 2020 and June 2021. The Haller index (HI), correction index (CI), modified asymmetry index (AI), and modified eccentricity index (EI) were determined during free, quiet, and forced breathing respectively. Breathing-related differences in the thoracic indices were analyzed with the Wilcoxon signed-rank test. Motion of the anterior chest wall was analyzed as well. Results: A total of 56 patients (11 females and 45 males, median age 15.4 years, interquartile range 14.3–16.9) were included. In quiet expiration, the median HI in the cohort equaled 5.7 (4.5–7.2). The median absolute differences (Δ) in the thoracic indices between peak inspiration and peak expiration were ΔHI = 1.1 (0.7–1.6, p &lt;.001), ΔCI = 4.8% (1.3–7.5%, p &lt;.001), ΔAI = 3.0% (1.0–5.0%, p &lt;.001), and ΔEI = 8.0% (3.0–14.0%, p &lt;.05). The indices varied significantly during different inspiratory phases, but not during expiration (p &gt;.05 each). Furthermore, the dynamic evaluation revealed three distinctive movement patterns of the funnel chest. Conclusions: Real-time MRI reveals patterns of chest wall motion and indicate that thoracic indices of pectus excavatum should be assessed in the end-expiratory phase of quiet expiration. Key Points: • The thoracic indices in patients with pectus excavatum depend on the breathing phase. • Quiet expiration represents the best breathing phase for determining thoracic indices. • Real-time MRI can identify different chest wall motion patterns in pectus excavatum. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: &lt;i&gt;Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=161963610
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s00330-022-09197-1
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 2128
    Subjects:
      – SubjectFull: Pectus excavatum
        Type: general
      – SubjectFull: Respiration
        Type: general
      – SubjectFull: Magnetic resonance imaging
        Type: general
      – SubjectFull: Rib abnormalities
        Type: general
      – SubjectFull: Sternum abnormalities
        Type: general
    Titles:
      – TitleFull: Pectus excavatum in motion: dynamic evaluation using real-time MRI.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Gräfe, Daniel
      – PersonEntity:
          Name:
            NameFull: Lacher, Martin
      – PersonEntity:
          Name:
            NameFull: Martynov, Illya
      – PersonEntity:
          Name:
            NameFull: Hirsch, Franz Wolfgang
      – PersonEntity:
          Name:
            NameFull: Voit, Dirk
      – PersonEntity:
          Name:
            NameFull: Frahm, Jens
      – PersonEntity:
          Name:
            NameFull: Busse, Harald
      – PersonEntity:
          Name:
            NameFull: Sesia, Sergio Bruno
      – PersonEntity:
          Name:
            NameFull: Krämer, Sebastian
      – PersonEntity:
          Name:
            NameFull: Zimmermann, Peter
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 03
              Text: Mar2023
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-print
              Value: 09387994
          Numbering:
            – Type: volume
              Value: 33
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: European Radiology
              Type: main
ResultId 1