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A computational design of experiments based method for evaluation of off-the-shelf total knee replacement implants.

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Title: A computational design of experiments based method for evaluation of off-the-shelf total knee replacement implants.
Authors: Burge, Thomas A.1 (AUTHOR), Jeffers, Jonathan R. T.2 (AUTHOR), Myant, Connor W.1 (AUTHOR)
Source: Computer Methods in Biomechanics & Biomedical Engineering. May2023, Vol. 26 Issue 6, p629-638. 10p.
Subjects: Total knee replacement, Knee, Experimental design, Evaluation methodology, Tibia
Abstract: A methodology to explore the design space of off-the-shelf total knee replacement implant designs is outlined. Generic femur component and tibia plate designs were scaled to thousands of sizes and virtually fitted to 244 test subjects. Various implant designs and sizing requirements between genders and ethnicities were evaluated. 5 sizes optimised via the methodology produced a good global fit for most subjects. However, clinically significant over/underhang was present in 19% of subjects for tibia plates and 25% for femur components, reducing to 11/20% with 8 sizes. The analysis highlighted subtly better fit performance was obtained using sizes with unequal spacing. [ABSTRACT FROM AUTHOR]
Copyright of Computer Methods in Biomechanics & Biomedical Engineering is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
An: 163111304
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PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
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  Data: A computational design of experiments based method for evaluation of off-the-shelf total knee replacement implants.
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  Data: <searchLink fieldCode="AR" term="%22Burge%2C+Thomas+A%2E%22">Burge, Thomas A.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Jeffers%2C+Jonathan+R%2E+T%2E%22">Jeffers, Jonathan R. T.</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Myant%2C+Connor+W%2E%22">Myant, Connor W.</searchLink><relatesTo>1</relatesTo> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Computer+Methods+in+Biomechanics+%26+Biomedical+Engineering%22">Computer Methods in Biomechanics & Biomedical Engineering</searchLink>. May2023, Vol. 26 Issue 6, p629-638. 10p.
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  Data: <searchLink fieldCode="DE" term="%22Total+knee+replacement%22">Total knee replacement</searchLink><br /><searchLink fieldCode="DE" term="%22Knee%22">Knee</searchLink><br /><searchLink fieldCode="DE" term="%22Experimental+design%22">Experimental design</searchLink><br /><searchLink fieldCode="DE" term="%22Evaluation+methodology%22">Evaluation methodology</searchLink><br /><searchLink fieldCode="DE" term="%22Tibia%22">Tibia</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: A methodology to explore the design space of off-the-shelf total knee replacement implant designs is outlined. Generic femur component and tibia plate designs were scaled to thousands of sizes and virtually fitted to 244 test subjects. Various implant designs and sizing requirements between genders and ethnicities were evaluated. 5 sizes optimised via the methodology produced a good global fit for most subjects. However, clinically significant over/underhang was present in 19% of subjects for tibia plates and 25% for femur components, reducing to 11/20% with 8 sizes. The analysis highlighted subtly better fit performance was obtained using sizes with unequal spacing. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Computer Methods in Biomechanics & Biomedical Engineering is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=163111304
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        Value: 10.1080/10255842.2022.2075224
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      – Code: eng
        Text: English
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      – SubjectFull: Total knee replacement
        Type: general
      – SubjectFull: Knee
        Type: general
      – SubjectFull: Experimental design
        Type: general
      – SubjectFull: Evaluation methodology
        Type: general
      – SubjectFull: Tibia
        Type: general
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      – TitleFull: A computational design of experiments based method for evaluation of off-the-shelf total knee replacement implants.
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              M: 05
              Text: May2023
              Type: published
              Y: 2023
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              Value: 26
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