View in EDS

Hydroxyapatite nucleation and growth modulated by amino acid-capped gold nanoparticles: An in vitro study.

Saved in:
Bibliographic Details
Title: Hydroxyapatite nucleation and growth modulated by amino acid-capped gold nanoparticles: An in vitro study.
Authors: Sari, Yessie W.1 (AUTHOR) yessie.sari@apps.ipb.ac.id, Tsalsabila, Annisa1,2 (AUTHOR), Saputra, Angga1 (AUTHOR), Nuzulia, Nur Aisyah1 (AUTHOR), Herbani, Yuliati2 (AUTHOR)
Source: Ceramics International. Jun2023:Part A, Vol. 49 Issue 11, p17166-17173. 8p.
Subjects: Discontinuous precipitation, Gold nanoparticles, Hydroxyapatite, X-ray powder diffraction, Bioactive glasses, Scanning electron microscopes
Abstract: Surface modification of biomaterials significantly influences implantable materials' surface reactivity to induce an apatite-like layer formation. This study observed the bioactivity and surface reactivity of modified biomaterials (calcium-deficient hydroxyapatite [CDHA] on amino acid-capped AuNPs [AA-AuNPs]) through immersion in simulated body fluid (SBF). AuNPs capped with eight different amino acids (AA)—both charged and polar uncharged AAs—showed the ability to induce the biomimetic hydroxyapatite formation. The presence of a hydroxyapatite peak in the X-ray powder diffraction (XRD) pattern indicated hydroxyapatite formation after all samples' immersion in SBF. Moreover, longer immersion time in SBF contributed to the nucleation and growth of hydroxyapatite shown by the changing of the crystal structure including lattice parameters, crystallinity index, and crystallite size. The XRD results confirmed that surface modification using AA-AuNPs significantly affected the orientation of the hydroxyapatite crystal, where AAs served as a binding site for Ca2+ and PO 4 3− ions. Furthermore, grayscale analysis based on scanning electron microscope images showed that charged AAs exhibited a role in hydroxyapatite nucleation and growth while polar uncharged AAs only contributed to hydroxyapatite growth. The calculated Ca/P ratio also confirmed the formation of hydroxyapatite from CDHA. XRD and scanning electron microscopy/energy-dispersive X-ray spectroscopy results signify the bioactivity of CDHA-modulated AA-AuNPs in hydroxyapatite formation for new bone tissue regeneration. [ABSTRACT FROM AUTHOR]
Copyright of Ceramics International is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 163229862
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Hydroxyapatite nucleation and growth modulated by amino acid-capped gold nanoparticles: An in vitro study.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Sari%2C+Yessie+W%2E%22">Sari, Yessie W.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> yessie.sari@apps.ipb.ac.id</i><br /><searchLink fieldCode="AR" term="%22Tsalsabila%2C+Annisa%22">Tsalsabila, Annisa</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Saputra%2C+Angga%22">Saputra, Angga</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nuzulia%2C+Nur+Aisyah%22">Nuzulia, Nur Aisyah</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Herbani%2C+Yuliati%22">Herbani, Yuliati</searchLink><relatesTo>2</relatesTo> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Ceramics+International%22">Ceramics International</searchLink>. Jun2023:Part A, Vol. 49 Issue 11, p17166-17173. 8p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Discontinuous+precipitation%22">Discontinuous precipitation</searchLink><br /><searchLink fieldCode="DE" term="%22Gold+nanoparticles%22">Gold nanoparticles</searchLink><br /><searchLink fieldCode="DE" term="%22Hydroxyapatite%22">Hydroxyapatite</searchLink><br /><searchLink fieldCode="DE" term="%22X-ray+powder+diffraction%22">X-ray powder diffraction</searchLink><br /><searchLink fieldCode="DE" term="%22Bioactive+glasses%22">Bioactive glasses</searchLink><br /><searchLink fieldCode="DE" term="%22Scanning+electron+microscopes%22">Scanning electron microscopes</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Surface modification of biomaterials significantly influences implantable materials' surface reactivity to induce an apatite-like layer formation. This study observed the bioactivity and surface reactivity of modified biomaterials (calcium-deficient hydroxyapatite [CDHA] on amino acid-capped AuNPs [AA-AuNPs]) through immersion in simulated body fluid (SBF). AuNPs capped with eight different amino acids (AA)—both charged and polar uncharged AAs—showed the ability to induce the biomimetic hydroxyapatite formation. The presence of a hydroxyapatite peak in the X-ray powder diffraction (XRD) pattern indicated hydroxyapatite formation after all samples' immersion in SBF. Moreover, longer immersion time in SBF contributed to the nucleation and growth of hydroxyapatite shown by the changing of the crystal structure including lattice parameters, crystallinity index, and crystallite size. The XRD results confirmed that surface modification using AA-AuNPs significantly affected the orientation of the hydroxyapatite crystal, where AAs served as a binding site for Ca2+ and PO 4 3− ions. Furthermore, grayscale analysis based on scanning electron microscope images showed that charged AAs exhibited a role in hydroxyapatite nucleation and growth while polar uncharged AAs only contributed to hydroxyapatite growth. The calculated Ca/P ratio also confirmed the formation of hydroxyapatite from CDHA. XRD and scanning electron microscopy/energy-dispersive X-ray spectroscopy results signify the bioactivity of CDHA-modulated AA-AuNPs in hydroxyapatite formation for new bone tissue regeneration. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Ceramics International is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=163229862
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.ceramint.2023.02.080
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 17166
    Subjects:
      – SubjectFull: Discontinuous precipitation
        Type: general
      – SubjectFull: Gold nanoparticles
        Type: general
      – SubjectFull: Hydroxyapatite
        Type: general
      – SubjectFull: X-ray powder diffraction
        Type: general
      – SubjectFull: Bioactive glasses
        Type: general
      – SubjectFull: Scanning electron microscopes
        Type: general
    Titles:
      – TitleFull: Hydroxyapatite nucleation and growth modulated by amino acid-capped gold nanoparticles: An in vitro study.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Sari, Yessie W.
      – PersonEntity:
          Name:
            NameFull: Tsalsabila, Annisa
      – PersonEntity:
          Name:
            NameFull: Saputra, Angga
      – PersonEntity:
          Name:
            NameFull: Nuzulia, Nur Aisyah
      – PersonEntity:
          Name:
            NameFull: Herbani, Yuliati
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 05
              M: 06
              Text: Jun2023:Part A
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-print
              Value: 02728842
          Numbering:
            – Type: volume
              Value: 49
            – Type: issue
              Value: 11
          Titles:
            – TitleFull: Ceramics International
              Type: main
ResultId 1