Picosecond laser‐induced hybrid groove structures on Ti‐6Al‐4V bio‐alloy to accelerate osseointegration.
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| Title: | Picosecond laser‐induced hybrid groove structures on Ti‐6Al‐4V bio‐alloy to accelerate osseointegration. |
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| Authors: | Kedia, S.1,2 (AUTHOR) skedia@barc.gov.in, Checker, R.2,3 (AUTHOR), Sandur, S. K.2,3 (AUTHOR), Nilaya, J. P.1,2 (AUTHOR) |
| Source: | Journal of Biomedical Materials Research, Part B: Applied Biomaterials. Oct2023, Vol. 111 Issue 10, p1775-1784. 10p. |
| Subjects: | Artificial implants, Osseointegration, Cell growth, Extracellular matrix, Surface topography |
| Abstract: | Regulating cell growth, extracellular matrix deposition and mineralization of artificial implants are some important parameters that decide the longevity of implants in the body. Picosecond laser‐induced hybrid groove structures have been shown to improve these properties of the Ti‐6Al‐4V bio‐alloy. Two hybrid structures containing groove patterns with periodic and non‐periodic substructures therein were generated on Ti‐6Al‐4V by varying the extent of laser pulse overlapping on sample surface. Laser‐induced alteration in surface topography, chemical composition and wettability of Ti‐6Al‐4V resulted in 3‐fold increase in the rate of hydroxyapatite growth, 2.5‐fold increment in protein adsorption and 2‐fold enhancement in cell adhesion in comparison to pristine sample. While the periodic substructure was found to guide cell growth, the nonperiodic sub structure offered homogenous growth leading to higher overall cell density on the substrate surface. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Biomedical Materials Research, Part B: Applied Biomaterials is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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