Strain-rate-dependent material properties of human lung parenchymal tissue using inverse finite element approach.
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| Title: | Strain-rate-dependent material properties of human lung parenchymal tissue using inverse finite element approach. |
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| Authors: | Pydi, Yeswanth S.1 (AUTHOR) pyeswantsai@gmail.com, Nath, Atri1 (AUTHOR), Chawla, Anoop1 (AUTHOR), Mukherjee, Sudipto1 (AUTHOR), Lalwani, Sanjeev2 (AUTHOR), Malhotra, Rajesh3 (AUTHOR), Datla, Naresh V.1 (AUTHOR) |
| Source: | Biomechanics & Modeling in Mechanobiology. Dec2023, Vol. 22 Issue 6, p2083-2096. 14p. |
| Subjects: | Strain rate, Toes, Traffic accidents, Lungs, Elastic modulus, Blunt trauma, Tissues |
| Abstract: | Automobile crashes and blunt trauma often lead to life-threatening thoracic injuries, especially to the lung tissues. These injuries can be simulated using finite element-based human body models that need dynamic material properties of lung tissue. The strain-rate-dependent material parameters of human parenchymal tissues were determined in this study using uniaxial quasi-static (1 mm/s) and dynamic (1.6, 3, and 5 m/s) compression tests. A bilinear material model was used to capture the nonlinear behavior of the lung tissue, which was implemented using a user-defined material in LS-DYNA. Inverse mapping using genetic algorithm-based optimization of all experimental data with the corresponding FE models yielded a set of strain-rate-dependent material parameters. The bilinear material parameters are obtained for the strain rates of 0.1, 100, 300, and 500 s−1. The estimated elastic modulus increased from 43 to 153 kPa, while the toe strain reduced from 0.39 to 0.29 when the strain rate was increased from 0.1 to 500 s−1. The optimized bilinear material properties of parenchymal tissue exhibit a piecewise linear relationship with the strain rate. [ABSTRACT FROM AUTHOR] |
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| Database: | Engineering Source |
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| Abstract: | Automobile crashes and blunt trauma often lead to life-threatening thoracic injuries, especially to the lung tissues. These injuries can be simulated using finite element-based human body models that need dynamic material properties of lung tissue. The strain-rate-dependent material parameters of human parenchymal tissues were determined in this study using uniaxial quasi-static (1 mm/s) and dynamic (1.6, 3, and 5 m/s) compression tests. A bilinear material model was used to capture the nonlinear behavior of the lung tissue, which was implemented using a user-defined material in LS-DYNA. Inverse mapping using genetic algorithm-based optimization of all experimental data with the corresponding FE models yielded a set of strain-rate-dependent material parameters. The bilinear material parameters are obtained for the strain rates of 0.1, 100, 300, and 500 s−1. The estimated elastic modulus increased from 43 to 153 kPa, while the toe strain reduced from 0.39 to 0.29 when the strain rate was increased from 0.1 to 500 s−1. The optimized bilinear material properties of parenchymal tissue exhibit a piecewise linear relationship with the strain rate. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 16177959 |
| DOI: | 10.1007/s10237-023-01751-0 |
