The Use of Cell-free Protein Synthesis to Push the Boundaries of Synthetic Biology.

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Title: The Use of Cell-free Protein Synthesis to Push the Boundaries of Synthetic Biology.
Authors: Kim, Kyu Jae1 (AUTHOR), Lee, So-Jeong1 (AUTHOR), Kim, Dong-Myung1 (AUTHOR) dmkim@cnu.ac.kr
Source: Biotechnology & Bioprocess Engineering. Dec2023, Vol. 28 Issue 6, p922-928. 7p.
Subjects: Protein synthesis, Synthetic biology, Biological systems, Green business, Artificial cells, Recombinant proteins
Abstract: Cell-free protein synthesis is emerging as a powerful tool to accelerate the progress of synthetic biology. Notably, cell-free systems that harness extracted synthetic machinery of cells can address many of the issues associated with the complexity and variability of living systems. In particular, cell-free systems can be programmed with various configurations of genetic information, providing great flexibility and accessibility to the field of synthetic biology. Empowered by recent progress, cell-free systems are now evolving into artificial biological systems that can be tailored for various applications, including on-demand biomanufacturing, diagnostics, and new materials design. Here, we review the key developments related to cell-free protein synthesis systems, and discuss the future directions of these promising technologies. [ABSTRACT FROM AUTHOR]
Copyright of Biotechnology & Bioprocess Engineering is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: The Use of Cell-free Protein Synthesis to Push the Boundaries of Synthetic Biology.
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  Data: <searchLink fieldCode="AR" term="%22Kim%2C+Kyu+Jae%22">Kim, Kyu Jae</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lee%2C+So-Jeong%22">Lee, So-Jeong</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim%2C+Dong-Myung%22">Kim, Dong-Myung</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> dmkim@cnu.ac.kr</i>
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  Data: <searchLink fieldCode="JN" term="%22Biotechnology+%26+Bioprocess+Engineering%22">Biotechnology & Bioprocess Engineering</searchLink>. Dec2023, Vol. 28 Issue 6, p922-928. 7p.
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  Data: <searchLink fieldCode="DE" term="%22Protein+synthesis%22">Protein synthesis</searchLink><br /><searchLink fieldCode="DE" term="%22Synthetic+biology%22">Synthetic biology</searchLink><br /><searchLink fieldCode="DE" term="%22Biological+systems%22">Biological systems</searchLink><br /><searchLink fieldCode="DE" term="%22Green+business%22">Green business</searchLink><br /><searchLink fieldCode="DE" term="%22Artificial+cells%22">Artificial cells</searchLink><br /><searchLink fieldCode="DE" term="%22Recombinant+proteins%22">Recombinant proteins</searchLink>
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  Label: Abstract
  Group: Ab
  Data: Cell-free protein synthesis is emerging as a powerful tool to accelerate the progress of synthetic biology. Notably, cell-free systems that harness extracted synthetic machinery of cells can address many of the issues associated with the complexity and variability of living systems. In particular, cell-free systems can be programmed with various configurations of genetic information, providing great flexibility and accessibility to the field of synthetic biology. Empowered by recent progress, cell-free systems are now evolving into artificial biological systems that can be tailored for various applications, including on-demand biomanufacturing, diagnostics, and new materials design. Here, we review the key developments related to cell-free protein synthesis systems, and discuss the future directions of these promising technologies. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Biotechnology & Bioprocess Engineering is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1007/s12257-022-0279-2
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      – Code: eng
        Text: English
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      – SubjectFull: Protein synthesis
        Type: general
      – SubjectFull: Synthetic biology
        Type: general
      – SubjectFull: Biological systems
        Type: general
      – SubjectFull: Green business
        Type: general
      – SubjectFull: Artificial cells
        Type: general
      – SubjectFull: Recombinant proteins
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      – TitleFull: The Use of Cell-free Protein Synthesis to Push the Boundaries of Synthetic Biology.
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            NameFull: Kim, Kyu Jae
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            NameFull: Lee, So-Jeong
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              M: 12
              Text: Dec2023
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              Y: 2023
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