The Probability of Defibrillation Success and the Incidence of Postshock Arrhythmia as a Function of Shock Strength.

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Title: The Probability of Defibrillation Success and the Incidence of Postshock Arrhythmia as a Function of Shock Strength.
Authors: Gates, Adam W.1,2, Wolf, Patrick D.1,2, Hillsley, Russell E.1,2, Souza, Joseph J.3, Smith, William M.1,2, Ideker, Raymond E.1,2
Source: Pacing & Clinical Electrophysiology. Jul1994, Vol. 17 Issue 7, p1208-1217. 10p.
Subjects: Electric countershock, Cardiac resuscitation, Arrhythmia, Electrodes, Right heart ventricle, Electrotherapeutics
Abstract: The effects of high voltage defibrillation shocks given to six swine were studied to determine if there is a limit to the advantage gained from increasing the shock strength. An endocardial electrode was placed in the right ventricle, and a 114-cm² cutaneous patch was placed on the left lateral thorax. Monophasic (10 msec) and single capacitor biphosic (5/5 msec) shocks with leading edge voltages of 200, 400, 600, 800, and 990 volts (approximately 2.3-59 J) were tested. For monophasic shocks, the probability of successful defibrillation ranged from 0% at 200 V to 90% at 990 V. The incidence of postshock arrhythmia increased from 0% for successful shocks at 600 V to 67% for successful shocks at 990 V. For biphasic shocks, the probability of success peaked at 97% for the 600-, 800-, and 990-V shocks. The incidence of postshock arrhythmia increased from 8% at 400 V to 55% at 990 V. Although more postshock arrhythmias occurred at lower strengths for biphasic than for monophasic shocks, an efficacy criterion, quantifying the probability of defibrillation success acid the probability that a postshock arrhythmia will not occur, was always higher for biphasic shocks. The probability of success never reached 100% for either waveform while the incidence of postshock arrhythmia increased as the shock strength increased. In conclusion, for the catheter-patch electrode configuration, increasing the shock strength does not always improve the probability of success and may increase the incidence of postshock arrhythmia. [ABSTRACT FROM AUTHOR]
Copyright of Pacing & Clinical Electrophysiology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: The Probability of Defibrillation Success and the Incidence of Postshock Arrhythmia as a Function of Shock Strength.
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  Data: <searchLink fieldCode="DE" term="%22Electric+countershock%22">Electric countershock</searchLink><br /><searchLink fieldCode="DE" term="%22Cardiac+resuscitation%22">Cardiac resuscitation</searchLink><br /><searchLink fieldCode="DE" term="%22Arrhythmia%22">Arrhythmia</searchLink><br /><searchLink fieldCode="DE" term="%22Electrodes%22">Electrodes</searchLink><br /><searchLink fieldCode="DE" term="%22Right+heart+ventricle%22">Right heart ventricle</searchLink><br /><searchLink fieldCode="DE" term="%22Electrotherapeutics%22">Electrotherapeutics</searchLink>
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  Data: The effects of high voltage defibrillation shocks given to six swine were studied to determine if there is a limit to the advantage gained from increasing the shock strength. An endocardial electrode was placed in the right ventricle, and a 114-cm² cutaneous patch was placed on the left lateral thorax. Monophasic (10 msec) and single capacitor biphosic (5/5 msec) shocks with leading edge voltages of 200, 400, 600, 800, and 990 volts (approximately 2.3-59 J) were tested. For monophasic shocks, the probability of successful defibrillation ranged from 0% at 200 V to 90% at 990 V. The incidence of postshock arrhythmia increased from 0% for successful shocks at 600 V to 67% for successful shocks at 990 V. For biphasic shocks, the probability of success peaked at 97% for the 600-, 800-, and 990-V shocks. The incidence of postshock arrhythmia increased from 8% at 400 V to 55% at 990 V. Although more postshock arrhythmias occurred at lower strengths for biphasic than for monophasic shocks, an efficacy criterion, quantifying the probability of defibrillation success acid the probability that a postshock arrhythmia will not occur, was always higher for biphasic shocks. The probability of success never reached 100% for either waveform while the incidence of postshock arrhythmia increased as the shock strength increased. In conclusion, for the catheter-patch electrode configuration, increasing the shock strength does not always improve the probability of success and may increase the incidence of postshock arrhythmia. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of Pacing & Clinical Electrophysiology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1111/j.1540-8159.1994.tb01487.x
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      – Code: eng
        Text: English
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        PageCount: 10
        StartPage: 1208
    Subjects:
      – SubjectFull: Electric countershock
        Type: general
      – SubjectFull: Cardiac resuscitation
        Type: general
      – SubjectFull: Arrhythmia
        Type: general
      – SubjectFull: Electrodes
        Type: general
      – SubjectFull: Right heart ventricle
        Type: general
      – SubjectFull: Electrotherapeutics
        Type: general
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      – TitleFull: The Probability of Defibrillation Success and the Incidence of Postshock Arrhythmia as a Function of Shock Strength.
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            NameFull: Gates, Adam W.
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            NameFull: Wolf, Patrick D.
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            NameFull: Hillsley, Russell E.
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            NameFull: Souza, Joseph J.
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            NameFull: Smith, William M.
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              M: 07
              Text: Jul1994
              Type: published
              Y: 1994
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