Reduction in Energy Pacing Thresholds by Overlapping Biphasic Stimulation Versus Conventional Bipolar Pacing.

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Title: Reduction in Energy Pacing Thresholds by Overlapping Biphasic Stimulation Versus Conventional Bipolar Pacing.
Authors: Lazarus, A.1 Alazarusl@aol.com, Taskiran, M.2, Ritter, P.1, Gras, D.1, Cazeau, S.1, Mugica, J.1
Source: Pacing & Clinical Electrophysiology. Nov1998, Vol. 21 Issue 11, p2166-2170. 5p.
Subjects: Cardiac pacing, Cardiac pacemakers, Electrodes, Lead, Heart atrium, Myocardium, Implanted cardiovascular instruments
Abstract: Overlapping biphasic (OLBI) stimulation is a new pacing waveform consisting of two simultaneous monophasic pulses of opposite polarities applied to a bipolar electrode. The goal of this prospective study was to compare, using conventional pacing leads, the acute energy pacing thresholds, measured at 0.5-ms pulse duration, associated with bipolar versus OLBI (mode 7 and mode 8) pulse delivery. Results: Thirty one leads were tested in 20 patients. Of these leads, 7 (23%) were implanted chronically, 12 (39%) were in atrial positions, and 19 (61%) in ventricular positions. Energy pacing thresholds were significantly lower (-25.6 ± 25.6 %, P = 0.005) in OLBI mode 8 (1.30 ± 3.96 μJ) compared to bipolar (1.55 ± 4.37 μJ) pacing, regardless of the pacing site or length of service of the leads. In contrast, OLBI mode 7, which has an anodal component, at the tip electrode was associated with higher energy pacing thresholds (3.65 ± 6.48 μJ; +358.3 ± 219.4%, P = 0.002). Conclusions: Mode 8 OLBI pacing is associated with lower acute energy pacing thresholds when used with bipolar leads in contact with the myocardium. OLBI pacing may increase pacemaker longevity by reducing long-term energy consumption. [ABSTRACT FROM AUTHOR]
Copyright of Pacing & Clinical Electrophysiology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Label: Title
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  Data: Reduction in Energy Pacing Thresholds by Overlapping Biphasic Stimulation Versus Conventional Bipolar Pacing.
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  Data: <searchLink fieldCode="AR" term="%22Lazarus%2C+A%2E%22">Lazarus, A.</searchLink><relatesTo>1</relatesTo><i> Alazarusl@aol.com</i><br /><searchLink fieldCode="AR" term="%22Taskiran%2C+M%2E%22">Taskiran, M.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Ritter%2C+P%2E%22">Ritter, P.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Gras%2C+D%2E%22">Gras, D.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Cazeau%2C+S%2E%22">Cazeau, S.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Mugica%2C+J%2E%22">Mugica, J.</searchLink><relatesTo>1</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Pacing+%26+Clinical+Electrophysiology%22">Pacing & Clinical Electrophysiology</searchLink>. Nov1998, Vol. 21 Issue 11, p2166-2170. 5p.
– Name: Subject
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  Data: <searchLink fieldCode="DE" term="%22Cardiac+pacing%22">Cardiac pacing</searchLink><br /><searchLink fieldCode="DE" term="%22Cardiac+pacemakers%22">Cardiac pacemakers</searchLink><br /><searchLink fieldCode="DE" term="%22Electrodes%22">Electrodes</searchLink><br /><searchLink fieldCode="DE" term="%22Lead%22">Lead</searchLink><br /><searchLink fieldCode="DE" term="%22Heart+atrium%22">Heart atrium</searchLink><br /><searchLink fieldCode="DE" term="%22Myocardium%22">Myocardium</searchLink><br /><searchLink fieldCode="DE" term="%22Implanted+cardiovascular+instruments%22">Implanted cardiovascular instruments</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Overlapping biphasic (OLBI) stimulation is a new pacing waveform consisting of two simultaneous monophasic pulses of opposite polarities applied to a bipolar electrode. The goal of this prospective study was to compare, using conventional pacing leads, the acute energy pacing thresholds, measured at 0.5-ms pulse duration, associated with bipolar versus OLBI (mode 7 and mode 8) pulse delivery. Results: Thirty one leads were tested in 20 patients. Of these leads, 7 (23%) were implanted chronically, 12 (39%) were in atrial positions, and 19 (61%) in ventricular positions. Energy pacing thresholds were significantly lower (-25.6 ± 25.6 %, P = 0.005) in OLBI mode 8 (1.30 ± 3.96 μJ) compared to bipolar (1.55 ± 4.37 μJ) pacing, regardless of the pacing site or length of service of the leads. In contrast, OLBI mode 7, which has an anodal component, at the tip electrode was associated with higher energy pacing thresholds (3.65 ± 6.48 μJ; +358.3 ± 219.4%, P = 0.002). Conclusions: Mode 8 OLBI pacing is associated with lower acute energy pacing thresholds when used with bipolar leads in contact with the myocardium. OLBI pacing may increase pacemaker longevity by reducing long-term energy consumption. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Pacing & Clinical Electrophysiology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1111/j.1540-8159.1998.tb01146.x
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      – Code: eng
        Text: English
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      – SubjectFull: Cardiac pacing
        Type: general
      – SubjectFull: Cardiac pacemakers
        Type: general
      – SubjectFull: Electrodes
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      – SubjectFull: Lead
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      – SubjectFull: Heart atrium
        Type: general
      – SubjectFull: Myocardium
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      – SubjectFull: Implanted cardiovascular instruments
        Type: general
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      – TitleFull: Reduction in Energy Pacing Thresholds by Overlapping Biphasic Stimulation Versus Conventional Bipolar Pacing.
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              Text: Nov1998
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              Y: 1998
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