Risk of Complications of Atrial Fibrillation.

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Title: Risk of Complications of Atrial Fibrillation.
Authors: Capucci, Alessandro1, Villani, Giovanni Quinto1, Aschieri, Daniela1
Source: Pacing & Clinical Electrophysiology. Oct1997, Vol. 20 Issue 10, p2684-2691. 8p.
Subjects: Atrial fibrillation, Disease complications, Atrial arrhythmias, Thromboembolism, Hemodynamics, Embolisms
Abstract: Fibrillation. Atrial fibrillation is associated with three major risk of complications: thromboembolism, hemodynamic compromise, and arrhythmogenesis. In patients with chronic atrial fibrillation the incidence of embolization is about 5% per year. The risk of embolism and in particular of stroke can be reduced by warfarine anticoagulation. Aspirin is generally less effective than warfarin, although it is probably more effective than placebo. The hemodynamic complications which may occur during atrial fibrillation are mainly due to the loss of effective atrial contraction, the irregular ventricular rhythm, and the possible excessively rapid ventricular rate. Sudden death is a recognized manifestation of Wolff-Parkinson-White syndrome and is considered to be precipitated by atrial fibrillation in the majority of patients. Torsades de pointes is perhaps the most widely recognized proarrhythmia associated with treatment of atrial fibrillation, especially with lA antiarrhythmic drugs and sotalol. The chronic treatment with type lC drugs in 3.5%-5% of patients may induce atrial flutter with 1:1 conduction with significant hemodynamic compromise. [ABSTRACT FROM AUTHOR]
Copyright of Pacing & Clinical Electrophysiology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Risk of Complications of Atrial Fibrillation.
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  Data: <searchLink fieldCode="AR" term="%22Capucci%2C+Alessandro%22">Capucci, Alessandro</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Villani%2C+Giovanni+Quinto%22">Villani, Giovanni Quinto</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Aschieri%2C+Daniela%22">Aschieri, Daniela</searchLink><relatesTo>1</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Pacing+%26+Clinical+Electrophysiology%22">Pacing & Clinical Electrophysiology</searchLink>. Oct1997, Vol. 20 Issue 10, p2684-2691. 8p.
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  Data: <searchLink fieldCode="DE" term="%22Atrial+fibrillation%22">Atrial fibrillation</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+complications%22">Disease complications</searchLink><br /><searchLink fieldCode="DE" term="%22Atrial+arrhythmias%22">Atrial arrhythmias</searchLink><br /><searchLink fieldCode="DE" term="%22Thromboembolism%22">Thromboembolism</searchLink><br /><searchLink fieldCode="DE" term="%22Hemodynamics%22">Hemodynamics</searchLink><br /><searchLink fieldCode="DE" term="%22Embolisms%22">Embolisms</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Fibrillation. Atrial fibrillation is associated with three major risk of complications: thromboembolism, hemodynamic compromise, and arrhythmogenesis. In patients with chronic atrial fibrillation the incidence of embolization is about 5% per year. The risk of embolism and in particular of stroke can be reduced by warfarine anticoagulation. Aspirin is generally less effective than warfarin, although it is probably more effective than placebo. The hemodynamic complications which may occur during atrial fibrillation are mainly due to the loss of effective atrial contraction, the irregular ventricular rhythm, and the possible excessively rapid ventricular rate. Sudden death is a recognized manifestation of Wolff-Parkinson-White syndrome and is considered to be precipitated by atrial fibrillation in the majority of patients. Torsades de pointes is perhaps the most widely recognized proarrhythmia associated with treatment of atrial fibrillation, especially with lA antiarrhythmic drugs and sotalol. The chronic treatment with type lC drugs in 3.5%-5% of patients may induce atrial flutter with 1:1 conduction with significant hemodynamic compromise. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Group: Ab
  Data: <i>Copyright of Pacing & Clinical Electrophysiology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1111/j.1540-8159.1997.tb06117.x
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      – Code: eng
        Text: English
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        PageCount: 8
        StartPage: 2684
    Subjects:
      – SubjectFull: Atrial fibrillation
        Type: general
      – SubjectFull: Disease complications
        Type: general
      – SubjectFull: Atrial arrhythmias
        Type: general
      – SubjectFull: Thromboembolism
        Type: general
      – SubjectFull: Hemodynamics
        Type: general
      – SubjectFull: Embolisms
        Type: general
    Titles:
      – TitleFull: Risk of Complications of Atrial Fibrillation.
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            NameFull: Capucci, Alessandro
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            NameFull: Villani, Giovanni Quinto
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            NameFull: Aschieri, Daniela
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            – D: 15
              M: 10
              Text: Oct1997
              Type: published
              Y: 1997
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            – TitleFull: Pacing & Clinical Electrophysiology
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