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Any‐nucleus distributed active programmable transmit coil.

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Title: Any‐nucleus distributed active programmable transmit coil.
Authors: Han, Victor1 (AUTHOR), Reeder, Charlie P.1 (AUTHOR), Hernández‐Morales, Miriam1,2 (AUTHOR), Liu, Chunlei1,2 (AUTHOR) chunlei.liu@berkeley.edu
Source: Magnetic Resonance in Medicine. Jul2024, Vol. 92 Issue 1, p389-405. 17p.
Subjects: Real-time programming, Semiconductor switches, Magnetic fields
Abstract: Purpose: There are 118 known elements. Nearly all of them have NMR active isotopes and at least 39 different nuclei have biological relevance. Despite this, most of today's MRI is based on only one nucleus—1H. To facilitate imaging all potential nuclei, we present a single transmit coil able to excite arbitrary nuclei in human‐scale MRI. Theory and Methods: We present a completely new type of RF coil, the Any‐nucleus Distributed Active Programmable Transmit Coil (ADAPT Coil), with fast switches integrated into the structure of the coil to allow it to operate at any relevant frequency. This coil eliminates the need for the expensive traditional RF amplifier by directly converting direct current (DC) power into RF magnetic fields with frequencies chosen by digital control signals sent to the switches. Semiconductor switch imperfections are overcome by segmenting the coil. Results: Circuit simulations demonstrated the effectiveness of the ADAPT Coil approach, and a 9 cm diameter surface ADAPT Coil was implemented. Using the ADAPT Coil, 1H, 23Na, 2H, and 13C phantom images were acquired, and 1H and 23Na ex vivo images were acquired. To excite different nuclei, only digital control signals were changed, which can be programmed in real time. Conclusion: The ADAPT Coil presents a low‐cost, scalable, and efficient method for exciting arbitrary nuclei in human‐scale MRI. This coil concept provides further opportunities for scaling, programmability, lowering coil costs, lowering dead‐time, streamlining multinuclear MRI workflows, and enabling the study of dozens of biologically relevant nuclei. [ABSTRACT FROM AUTHOR]
Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Any‐nucleus distributed active programmable transmit coil.
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  Data: <searchLink fieldCode="AR" term="%22Han%2C+Victor%22">Han, Victor</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Reeder%2C+Charlie+P%2E%22">Reeder, Charlie P.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hernández‐Morales%2C+Miriam%22">Hernández‐Morales, Miriam</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liu%2C+Chunlei%22">Liu, Chunlei</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> chunlei.liu@berkeley.edu</i>
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  Data: <searchLink fieldCode="JN" term="%22Magnetic+Resonance+in+Medicine%22">Magnetic Resonance in Medicine</searchLink>. Jul2024, Vol. 92 Issue 1, p389-405. 17p.
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– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Purpose: There are 118 known elements. Nearly all of them have NMR active isotopes and at least 39 different nuclei have biological relevance. Despite this, most of today's MRI is based on only one nucleus—1H. To facilitate imaging all potential nuclei, we present a single transmit coil able to excite arbitrary nuclei in human‐scale MRI. Theory and Methods: We present a completely new type of RF coil, the Any‐nucleus Distributed Active Programmable Transmit Coil (ADAPT Coil), with fast switches integrated into the structure of the coil to allow it to operate at any relevant frequency. This coil eliminates the need for the expensive traditional RF amplifier by directly converting direct current (DC) power into RF magnetic fields with frequencies chosen by digital control signals sent to the switches. Semiconductor switch imperfections are overcome by segmenting the coil. Results: Circuit simulations demonstrated the effectiveness of the ADAPT Coil approach, and a 9 cm diameter surface ADAPT Coil was implemented. Using the ADAPT Coil, 1H, 23Na, 2H, and 13C phantom images were acquired, and 1H and 23Na ex vivo images were acquired. To excite different nuclei, only digital control signals were changed, which can be programmed in real time. Conclusion: The ADAPT Coil presents a low‐cost, scalable, and efficient method for exciting arbitrary nuclei in human‐scale MRI. This coil concept provides further opportunities for scaling, programmability, lowering coil costs, lowering dead‐time, streamlining multinuclear MRI workflows, and enabling the study of dozens of biologically relevant nuclei. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1002/mrm.30044
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        Text: English
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      – SubjectFull: Real-time programming
        Type: general
      – SubjectFull: Semiconductor switches
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      – SubjectFull: Magnetic fields
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      – TitleFull: Any‐nucleus distributed active programmable transmit coil.
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            NameFull: Reeder, Charlie P.
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            NameFull: Hernández‐Morales, Miriam
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            NameFull: Liu, Chunlei
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            – D: 01
              M: 07
              Text: Jul2024
              Type: published
              Y: 2024
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