Molecular vessels from preorganised natural building blocks.
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| Title: | Molecular vessels from preorganised natural building blocks. |
|---|---|
| Authors: | Llamosí, Arturo1 (AUTHOR), Szymański, Marek P.1 (AUTHOR), Szumna, Agnieszka1 (AUTHOR) agnieszka.szumna@icho.edu.pl |
| Source: | Chemical Society Reviews. 5/7/2024, Vol. 53 Issue 9, p4434-4462. 29p. |
| Subjects: | Multivalent molecules, Crown ethers, Cyclodextrins, Building design & construction, Resorcinol, Metalloporphyrins, Carbohydrates |
| Abstract: | Supramolecular vessels emerged as tools to mimic and better understand compartmentalisation, a central aspect of living matter. However, many more applications that go beyond those initial goals have been documented in recent years, including new sensory systems, artificial transmembrane transporters, catalysis, and targeted drug or gene delivery. Peptides, carbohydrates, nucleobases, and steroids bear great potential as building blocks for the construction of supramolecular vessels, possessing complexity that is still difficult to attain with synthetic methods – they are rich in functional groups and well-defined stereogenic centers, ready for noncovalent interactions and further functions. One of the options to tame the functional and dynamic complexity of natural building blocks is to place them at spatially designed positions using synthetic scaffolds. In this review, we summarise the historical and recent advances in the construction of molecular-sized vessels by the strategy that couples synthetic predictability and durability of various scaffolds (cyclodextrins, porphyrins, crown ethers, calix[n]arenes, resorcin[n]arenes, pillar[n]arenes, cyclotriveratrylenes, coordination frameworks and multivalent high-symmetry molecules) with functionality originating from natural building blocks to obtain nanocontainers, cages, capsules, cavitands, carcerands or coordination cages by covalent chemistry, self-assembly, or dynamic covalent chemistry with the ultimate goal to apply them in sensing, transport, or catalysis. [ABSTRACT FROM AUTHOR] |
| Copyright of Chemical Society Reviews is the property of Royal Society of Chemistry and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 177090703 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Molecular vessels from preorganised natural building blocks. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Llamosí%2C+Arturo%22">Llamosí, Arturo</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Szymański%2C+Marek+P%2E%22">Szymański, Marek P.</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Szumna%2C+Agnieszka%22">Szumna, Agnieszka</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> agnieszka.szumna@icho.edu.pl</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Chemical+Society+Reviews%22">Chemical Society Reviews</searchLink>. 5/7/2024, Vol. 53 Issue 9, p4434-4462. 29p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Multivalent+molecules%22">Multivalent molecules</searchLink><br /><searchLink fieldCode="DE" term="%22Crown+ethers%22">Crown ethers</searchLink><br /><searchLink fieldCode="DE" term="%22Cyclodextrins%22">Cyclodextrins</searchLink><br /><searchLink fieldCode="DE" term="%22Building+design+%26+construction%22">Building design & construction</searchLink><br /><searchLink fieldCode="DE" term="%22Resorcinol%22">Resorcinol</searchLink><br /><searchLink fieldCode="DE" term="%22Metalloporphyrins%22">Metalloporphyrins</searchLink><br /><searchLink fieldCode="DE" term="%22Carbohydrates%22">Carbohydrates</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Supramolecular vessels emerged as tools to mimic and better understand compartmentalisation, a central aspect of living matter. However, many more applications that go beyond those initial goals have been documented in recent years, including new sensory systems, artificial transmembrane transporters, catalysis, and targeted drug or gene delivery. Peptides, carbohydrates, nucleobases, and steroids bear great potential as building blocks for the construction of supramolecular vessels, possessing complexity that is still difficult to attain with synthetic methods – they are rich in functional groups and well-defined stereogenic centers, ready for noncovalent interactions and further functions. One of the options to tame the functional and dynamic complexity of natural building blocks is to place them at spatially designed positions using synthetic scaffolds. In this review, we summarise the historical and recent advances in the construction of molecular-sized vessels by the strategy that couples synthetic predictability and durability of various scaffolds (cyclodextrins, porphyrins, crown ethers, calix[n]arenes, resorcin[n]arenes, pillar[n]arenes, cyclotriveratrylenes, coordination frameworks and multivalent high-symmetry molecules) with functionality originating from natural building blocks to obtain nanocontainers, cages, capsules, cavitands, carcerands or coordination cages by covalent chemistry, self-assembly, or dynamic covalent chemistry with the ultimate goal to apply them in sensing, transport, or catalysis. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Chemical Society Reviews is the property of Royal Society of Chemistry and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1039/d3cs00801k Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 29 StartPage: 4434 Subjects: – SubjectFull: Multivalent molecules Type: general – SubjectFull: Crown ethers Type: general – SubjectFull: Cyclodextrins Type: general – SubjectFull: Building design & construction Type: general – SubjectFull: Resorcinol Type: general – SubjectFull: Metalloporphyrins Type: general – SubjectFull: Carbohydrates Type: general Titles: – TitleFull: Molecular vessels from preorganised natural building blocks. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Llamosí, Arturo – PersonEntity: Name: NameFull: Szymański, Marek P. – PersonEntity: Name: NameFull: Szumna, Agnieszka IsPartOfRelationships: – BibEntity: Dates: – D: 07 M: 05 Text: 5/7/2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 03060012 Numbering: – Type: volume Value: 53 – Type: issue Value: 9 Titles: – TitleFull: Chemical Society Reviews Type: main |
| ResultId | 1 |
