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Iridium oxide-based non-enzymatic glucose sensor: Superior electro-catalytic performance in biological environmental media.

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Title: Iridium oxide-based non-enzymatic glucose sensor: Superior electro-catalytic performance in biological environmental media.
Authors: Jeon, Ji Hwan1 (AUTHOR), Lim, Hyo-Ryoung2 (AUTHOR), Park, Ji Young1 (AUTHOR) jiyoung3073@hanyang.ac.kr, Choa, Yong-Ho1 (AUTHOR) choa15@hanyang.ac.kr
Source: Environmental Research. Jul2024:Part 2, Vol. 252, pN.PAG-N.PAG. 1p.
Subjects: Glucose analysis, Continuous glucose monitoring, Iridium, Glucose, Iridium oxide, Detectors, Extracellular fluid
Abstract: Nanostructured inorganic materials have potential advantages as glucose-sensing elements in diabetes care, thereby circumventing the need for expensive enzymatic agents. However, many nonenzymatic sensors face challenges related to selectivity and reliability, reducing their efficacy in body fluids. In this study, we introduce an Iridium oxide (IrO 2)-based non-enzymatic glucose sensor. This sensor demonstrates exceptional electro-catalytic properties in human serum, characterized by high sensitivity (638 μA μM−1cm2) and a consistent recovery rate (∼104%) across 15 cycles in saline. Furthermore, its impressive performance in human serum, as evidenced by a low relative standard deviation (RSD <1.57%), underscores its applicability in biological matrices such as interstitial fluids. Overall, the IrO 2 sensor is a promising, highly reversible, economical, and simple method for detecting glucose in continuous monitoring systems. [Display omitted] • Economical IrO 2 non-enzymatic glucose sensor with high sensitivity. • Optimized IrO 2 coating on Au layer ensures stability and robust adhesion. • Superior selectivity in presence of interferents in uric acid and ascorbic acid. • Demonstrated consistent recovery (∼104%) at IrO 2 of 300 cycles in human serum. • Biosensor offers broad linear range and notable stability in human serum. [ABSTRACT FROM AUTHOR]
Copyright of Environmental Research is the property of Academic Press Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
An: 177630319
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PubTypeId: academicJournal
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  Data: Iridium oxide-based non-enzymatic glucose sensor: Superior electro-catalytic performance in biological environmental media.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Jeon%2C+Ji+Hwan%22&quot;&gt;Jeon, Ji Hwan&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lim%2C+Hyo-Ryoung%22&quot;&gt;Lim, Hyo-Ryoung&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Park%2C+Ji+Young%22&quot;&gt;Park, Ji Young&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt; (AUTHOR)&lt;i&gt; jiyoung3073@hanyang.ac.kr&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Choa%2C+Yong-Ho%22&quot;&gt;Choa, Yong-Ho&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt; (AUTHOR)&lt;i&gt; choa15@hanyang.ac.kr&lt;/i&gt;
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Environmental+Research%22&quot;&gt;Environmental Research&lt;/searchLink&gt;. Jul2024:Part 2, Vol. 252, pN.PAG-N.PAG. 1p.
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– Name: Abstract
  Label: Abstract
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  Data: Nanostructured inorganic materials have potential advantages as glucose-sensing elements in diabetes care, thereby circumventing the need for expensive enzymatic agents. However, many nonenzymatic sensors face challenges related to selectivity and reliability, reducing their efficacy in body fluids. In this study, we introduce an Iridium oxide (IrO 2)-based non-enzymatic glucose sensor. This sensor demonstrates exceptional electro-catalytic properties in human serum, characterized by high sensitivity (638 μA μM−1cm2) and a consistent recovery rate (∼104%) across 15 cycles in saline. Furthermore, its impressive performance in human serum, as evidenced by a low relative standard deviation (RSD &lt;1.57%), underscores its applicability in biological matrices such as interstitial fluids. Overall, the IrO 2 sensor is a promising, highly reversible, economical, and simple method for detecting glucose in continuous monitoring systems. [Display omitted] • Economical IrO 2 non-enzymatic glucose sensor with high sensitivity. • Optimized IrO 2 coating on Au layer ensures stability and robust adhesion. • Superior selectivity in presence of interferents in uric acid and ascorbic acid. • Demonstrated consistent recovery (∼104%) at IrO 2 of 300 cycles in human serum. • Biosensor offers broad linear range and notable stability in human serum. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: &lt;i&gt;Copyright of Environmental Research is the property of Academic Press Inc. and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.envres.2024.118772
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 1
        StartPage: N.PAG
    Subjects:
      – SubjectFull: Glucose analysis
        Type: general
      – SubjectFull: Continuous glucose monitoring
        Type: general
      – SubjectFull: Iridium
        Type: general
      – SubjectFull: Glucose
        Type: general
      – SubjectFull: Iridium oxide
        Type: general
      – SubjectFull: Detectors
        Type: general
      – SubjectFull: Extracellular fluid
        Type: general
    Titles:
      – TitleFull: Iridium oxide-based non-enzymatic glucose sensor: Superior electro-catalytic performance in biological environmental media.
        Type: main
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      – PersonEntity:
          Name:
            NameFull: Jeon, Ji Hwan
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            NameFull: Lim, Hyo-Ryoung
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            NameFull: Park, Ji Young
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            NameFull: Choa, Yong-Ho
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          Dates:
            – D: 05
              M: 07
              Text: Jul2024:Part 2
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-print
              Value: 00139351
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            – Type: volume
              Value: 252
          Titles:
            – TitleFull: Environmental Research
              Type: main
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