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Design and characterisation of a minibeam collimator utilising Monte Carlo simulation and a clinical linear accelerator.

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Title: Design and characterisation of a minibeam collimator utilising Monte Carlo simulation and a clinical linear accelerator.
Authors: Carver, Antony1 (AUTHOR), Baker, Sam2 (AUTHOR) samibaker1997@googlemail.com, Dumbill, Andrew1 (AUTHOR), Horton, Steven1 (AUTHOR), Green, Stuart1 (AUTHOR)
Source: Physics in Medicine & Biology. 7/7/2024, Vol. 69 Issue 13, p1-13. 13p.
Subjects: Linear accelerators, Monte Carlo method, Collimators, Photon beams, Proton therapy
Abstract: Objective. Spatially fractionated radiotherapy is showing promise as a treatment modality. Initial focus was on beams of photons at low energy produced from a synchrotron but more recently research has expanded to include applications in proton therapy. Interest in photon beams remains and this is the focus of this paper Approach. This study presents a 3D printed tungsten minibeam collimator intended to produce peak-to-valley dose ratios (PVDR) of between seven and ten with a 1 MV, bremsstrahlung generated, photon beam. The design of the collimator is motivated by a Monte Carlo study estimating the PVDR for different collimator designs at different energies. This collimator was characterised on a clinical linear accelerator (Elekta VersaHD) as well as an orthovoltage unit. Main results. The performance of the fabricated collimator was measured on Elekta VersaHD running in unflattened mode with a 6 MV beam. On the Elekta VersaHD units the PVDR was measured to be between approximately 1.5 and 2.0 at 3 cm deep. For measurements with the orthovoltage unit PVDRs of greater than 10 were observed at a depth of 4 cm. Significance. The results confirmed that the predictions from simulation could be reproduced on linear accelerators currently in clinical usage, producing PVDRs between 2–2.5. Using the model to predict PVDRs using 1 MV photon beams, the threshold considered to produce enhanced normal tissue dose tolerance ( > 7) was surpassed. This suggests the possibility of using such techniques with versions of existing Linac technology which have been modified to operate at low energy and high beam currents. [ABSTRACT FROM AUTHOR]
© 2025 IOP Publishing Ltd. All rights, including for text and data mining, AI training, and similar technologies, are reserved (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
An: 177991109
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Design and characterisation of a minibeam collimator utilising Monte Carlo simulation and a clinical linear accelerator.
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  Data: <searchLink fieldCode="AR" term="%22Carver%2C+Antony%22">Carver, Antony</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Baker%2C+Sam%22">Baker, Sam</searchLink><relatesTo>2</relatesTo> (AUTHOR)<i> samibaker1997@googlemail.com</i><br /><searchLink fieldCode="AR" term="%22Dumbill%2C+Andrew%22">Dumbill, Andrew</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Horton%2C+Steven%22">Horton, Steven</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Green%2C+Stuart%22">Green, Stuart</searchLink><relatesTo>1</relatesTo> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Physics+in+Medicine+%26+Biology%22">Physics in Medicine & Biology</searchLink>. 7/7/2024, Vol. 69 Issue 13, p1-13. 13p.
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  Data: <searchLink fieldCode="DE" term="%22Linear+accelerators%22">Linear accelerators</searchLink><br /><searchLink fieldCode="DE" term="%22Monte+Carlo+method%22">Monte Carlo method</searchLink><br /><searchLink fieldCode="DE" term="%22Collimators%22">Collimators</searchLink><br /><searchLink fieldCode="DE" term="%22Photon+beams%22">Photon beams</searchLink><br /><searchLink fieldCode="DE" term="%22Proton+therapy%22">Proton therapy</searchLink>
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  Label: Abstract
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  Data: Objective. Spatially fractionated radiotherapy is showing promise as a treatment modality. Initial focus was on beams of photons at low energy produced from a synchrotron but more recently research has expanded to include applications in proton therapy. Interest in photon beams remains and this is the focus of this paper Approach. This study presents a 3D printed tungsten minibeam collimator intended to produce peak-to-valley dose ratios (PVDR) of between seven and ten with a 1 MV, bremsstrahlung generated, photon beam. The design of the collimator is motivated by a Monte Carlo study estimating the PVDR for different collimator designs at different energies. This collimator was characterised on a clinical linear accelerator (Elekta VersaHD) as well as an orthovoltage unit. Main results. The performance of the fabricated collimator was measured on Elekta VersaHD running in unflattened mode with a 6 MV beam. On the Elekta VersaHD units the PVDR was measured to be between approximately 1.5 and 2.0 at 3 cm deep. For measurements with the orthovoltage unit PVDRs of greater than 10 were observed at a depth of 4 cm. Significance. The results confirmed that the predictions from simulation could be reproduced on linear accelerators currently in clinical usage, producing PVDRs between 2–2.5. Using the model to predict PVDRs using 1 MV photon beams, the threshold considered to produce enhanced normal tissue dose tolerance ( > 7) was surpassed. This suggests the possibility of using such techniques with versions of existing Linac technology which have been modified to operate at low energy and high beam currents. [ABSTRACT FROM AUTHOR]
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  Data: <i>© 2025 IOP Publishing Ltd. All rights, including for text and data mining, AI training, and similar technologies, are reserved</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1088/1361-6560/ad4d52
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      – Code: eng
        Text: English
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        PageCount: 13
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      – SubjectFull: Linear accelerators
        Type: general
      – SubjectFull: Monte Carlo method
        Type: general
      – SubjectFull: Collimators
        Type: general
      – SubjectFull: Photon beams
        Type: general
      – SubjectFull: Proton therapy
        Type: general
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            NameFull: Dumbill, Andrew
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              Text: 7/7/2024
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              Y: 2024
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