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An efficient protocol for commissioning radiophotoluminescence dosimeters for radiotherapy dosimetry audits.

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Title: An efficient protocol for commissioning radiophotoluminescence dosimeters for radiotherapy dosimetry audits.
Authors: Dimitriadis, Alexis1 (AUTHOR) Al.Dimitriadis@iaea.org, Kazantsev, Pavel1 (AUTHOR), Titovich, Egor1 (AUTHOR), Ule-Duque, Geraldyne1 (AUTHOR), Abdulrahim, Roua1 (AUTHOR), Magnus, Talent1 (AUTHOR), Azangwe, Godfrey1 (AUTHOR), Swamidas, Jamema1 (AUTHOR)
Source: Radiation Measurements. Sep2024, Vol. 177, pN.PAG-N.PAG. 1p.
Subjects: Medical dosimetry, Correction factors, Dosimeters, Standard deviations, Auditing
Abstract: The aim of this study was to develop an efficient protocol for the commissioning of 1000 radiophotoluminescence dosimeters (RPLDs) for use in postal dosimetry audits in radiotherapy. This involved the determination of correction factors necessary to reduce measurement uncertainty and ensure accurate dose measurements. The commissioning process started with the RPLDs subjected to a series of controlled irradiations to determine their individual nominal response. Experiments were also conducted to assess the influence of irradiation position, reading position, and ambient temperature on the dosimeter readings all which were accounted for calculating individual sensitivity correction factors (SCFs) for each dosimeter. Statistical analysis was performed to evaluate the variability of SCFs depending on normalization group. An additional investigation simulating different dosimetry audit batches was conducted to study the effect of SCF variability on dosimetry audit measurements. The adopted commissioning protocol required irradiation position correction factors (0.990–0.996), readout tray position correction factors (0.992–1.01) and room temperature corrections (∼0.4 % per ° C). This enabled the calculation of SCFs for a batch of 1000 RPLDs and the analysis found the majority of SCFs falling within the range of 0.985–1.015. The standard deviations of the SCF distributions were approximately 1% for all normalization groups. It was observed that SCFs normalized to the entire batch of 1000 dosimeters could be effectively used for smaller audit batches, with an additional uncertainty contribution of up to 0.2%. This minimal increase in uncertainty is acceptable within the context of dosimetry audits. The developed protocol for commissioning RPLDs provides a reliable method for ensuring accurate dose measurements in postal radiotherapy dosimetry audits. The correction factors applied during the commissioning process were thoroughly described to effectively minimize measurement uncertainty. The findings support the use of SCFs normalized to large dosimeter batches for smaller audit groups, thereby streamlining the dosimetry audit process. Future research should focus on the long-term stability of SCFs to further enhance the reliability of RPLD-based dosimetry audits. • An efficient protocol for commissioning radiophotoluminescence dosimeters for radiotherapy dosimetry audits is described. • The concepts of irradiation position correction, reading position correction and room temperature correction are presented complementing the available literature. • Sensitivity correction factors for radiophotoluminescence dosimeters are calculated and the uncertainties associated with them are evaluated. [ABSTRACT FROM AUTHOR]
Copyright of Radiation Measurements is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: An efficient protocol for commissioning radiophotoluminescence dosimeters for radiotherapy dosimetry audits.
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  Data: The aim of this study was to develop an efficient protocol for the commissioning of 1000 radiophotoluminescence dosimeters (RPLDs) for use in postal dosimetry audits in radiotherapy. This involved the determination of correction factors necessary to reduce measurement uncertainty and ensure accurate dose measurements. The commissioning process started with the RPLDs subjected to a series of controlled irradiations to determine their individual nominal response. Experiments were also conducted to assess the influence of irradiation position, reading position, and ambient temperature on the dosimeter readings all which were accounted for calculating individual sensitivity correction factors (SCFs) for each dosimeter. Statistical analysis was performed to evaluate the variability of SCFs depending on normalization group. An additional investigation simulating different dosimetry audit batches was conducted to study the effect of SCF variability on dosimetry audit measurements. The adopted commissioning protocol required irradiation position correction factors (0.990–0.996), readout tray position correction factors (0.992–1.01) and room temperature corrections (∼0.4 % per ° C). This enabled the calculation of SCFs for a batch of 1000 RPLDs and the analysis found the majority of SCFs falling within the range of 0.985–1.015. The standard deviations of the SCF distributions were approximately 1% for all normalization groups. It was observed that SCFs normalized to the entire batch of 1000 dosimeters could be effectively used for smaller audit batches, with an additional uncertainty contribution of up to 0.2%. This minimal increase in uncertainty is acceptable within the context of dosimetry audits. The developed protocol for commissioning RPLDs provides a reliable method for ensuring accurate dose measurements in postal radiotherapy dosimetry audits. The correction factors applied during the commissioning process were thoroughly described to effectively minimize measurement uncertainty. The findings support the use of SCFs normalized to large dosimeter batches for smaller audit groups, thereby streamlining the dosimetry audit process. Future research should focus on the long-term stability of SCFs to further enhance the reliability of RPLD-based dosimetry audits. • An efficient protocol for commissioning radiophotoluminescence dosimeters for radiotherapy dosimetry audits is described. • The concepts of irradiation position correction, reading position correction and room temperature correction are presented complementing the available literature. • Sensitivity correction factors for radiophotoluminescence dosimeters are calculated and the uncertainties associated with them are evaluated. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of Radiation Measurements is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.radmeas.2024.107268
    Languages:
      – Code: eng
        Text: English
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        PageCount: 1
        StartPage: N.PAG
    Subjects:
      – SubjectFull: Medical dosimetry
        Type: general
      – SubjectFull: Correction factors
        Type: general
      – SubjectFull: Dosimeters
        Type: general
      – SubjectFull: Standard deviations
        Type: general
      – SubjectFull: Auditing
        Type: general
    Titles:
      – TitleFull: An efficient protocol for commissioning radiophotoluminescence dosimeters for radiotherapy dosimetry audits.
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            – D: 01
              M: 09
              Text: Sep2024
              Type: published
              Y: 2024
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