Design, implementation and effectiveness of human fascia lata biomechanics for tissue engineering.

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Title: Design, implementation and effectiveness of human fascia lata biomechanics for tissue engineering.
Authors: Bonaldi, Lorenza1 (AUTHOR) lorenza.bonaldi@phd.unipd.it, Fontanella, Chiara Giulia1,2,3 (AUTHOR) chiaragiulia.fontanella@unipd.it, Stecco, Carla3,4 (AUTHOR) carla.stecco@unipd.it, Berardo, Alice1,3 (AUTHOR) alice.berardo@unipd.it
Source: Journal of Biomechanics. Nov2024, Vol. 176, pN.PAG-N.PAG. 1p.
Subjects: Scientific literature, Tensile strength, Young's modulus, Tissue mechanics, Tissue engineering
Abstract: The fascia lata (FL) is a multi-layered connective tissue with anisotropic mechanical behavior due to its fiber organization. It plays a key role in musculoskeletal functionality, making it important in tissue engineering. Understanding its mechanical response to stimuli like movement or applied pressure is crucial, as the elastic and viscoelastic behavior can vary significantly based on morphological characteristics, harvesting site, and load direction. Thus, the aim of this review is to summarise through a gap analysis the scientific literature on the biomechanical properties of the human FL, identifying all those features (from the experimental set up to its inherent structural variability) that could affect its biomechanical behaviour, and thus unveiling these emerging correlations. Our research reported key mechanical properties of the FL, such as Young's modulus, Ultimate Tensile Strength, failure strain, and anisotropic response, which are crucial for designing and applying obtained allografts and autografts in soft tissue repair. These insights can help surgeons optimize graft applications—selecting the proper harvesting location, technique, graft type, and suture size—and guide clinicians in rehabilitation for personalized medicine. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Biomechanics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
An: 180699261
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PubTypeId: academicJournal
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  Data: Design, implementation and effectiveness of human fascia lata biomechanics for tissue engineering.
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  Data: <searchLink fieldCode="AR" term="%22Bonaldi%2C+Lorenza%22">Bonaldi, Lorenza</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> lorenza.bonaldi@phd.unipd.it</i><br /><searchLink fieldCode="AR" term="%22Fontanella%2C+Chiara+Giulia%22">Fontanella, Chiara Giulia</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<i> chiaragiulia.fontanella@unipd.it</i><br /><searchLink fieldCode="AR" term="%22Stecco%2C+Carla%22">Stecco, Carla</searchLink><relatesTo>3,4</relatesTo> (AUTHOR)<i> carla.stecco@unipd.it</i><br /><searchLink fieldCode="AR" term="%22Berardo%2C+Alice%22">Berardo, Alice</searchLink><relatesTo>1,3</relatesTo> (AUTHOR)<i> alice.berardo@unipd.it</i>
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  Data: <searchLink fieldCode="DE" term="%22Scientific+literature%22">Scientific literature</searchLink><br /><searchLink fieldCode="DE" term="%22Tensile+strength%22">Tensile strength</searchLink><br /><searchLink fieldCode="DE" term="%22Young's+modulus%22">Young's modulus</searchLink><br /><searchLink fieldCode="DE" term="%22Tissue+mechanics%22">Tissue mechanics</searchLink><br /><searchLink fieldCode="DE" term="%22Tissue+engineering%22">Tissue engineering</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The fascia lata (FL) is a multi-layered connective tissue with anisotropic mechanical behavior due to its fiber organization. It plays a key role in musculoskeletal functionality, making it important in tissue engineering. Understanding its mechanical response to stimuli like movement or applied pressure is crucial, as the elastic and viscoelastic behavior can vary significantly based on morphological characteristics, harvesting site, and load direction. Thus, the aim of this review is to summarise through a gap analysis the scientific literature on the biomechanical properties of the human FL, identifying all those features (from the experimental set up to its inherent structural variability) that could affect its biomechanical behaviour, and thus unveiling these emerging correlations. Our research reported key mechanical properties of the FL, such as Young's modulus, Ultimate Tensile Strength, failure strain, and anisotropic response, which are crucial for designing and applying obtained allografts and autografts in soft tissue repair. These insights can help surgeons optimize graft applications—selecting the proper harvesting location, technique, graft type, and suture size—and guide clinicians in rehabilitation for personalized medicine. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Biomechanics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.jbiomech.2024.112369
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
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        PageCount: 1
        StartPage: N.PAG
    Subjects:
      – SubjectFull: Scientific literature
        Type: general
      – SubjectFull: Tensile strength
        Type: general
      – SubjectFull: Young's modulus
        Type: general
      – SubjectFull: Tissue mechanics
        Type: general
      – SubjectFull: Tissue engineering
        Type: general
    Titles:
      – TitleFull: Design, implementation and effectiveness of human fascia lata biomechanics for tissue engineering.
        Type: main
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            NameFull: Bonaldi, Lorenza
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            NameFull: Fontanella, Chiara Giulia
      – PersonEntity:
          Name:
            NameFull: Stecco, Carla
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            NameFull: Berardo, Alice
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          Dates:
            – D: 01
              M: 11
              Text: Nov2024
              Type: published
              Y: 2024
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              Value: 176
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            – TitleFull: Journal of Biomechanics
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