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Biomedical Applications of Aerogels: Therapeutic Potential, Safety, and Future Research Directions.

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Title: Biomedical Applications of Aerogels: Therapeutic Potential, Safety, and Future Research Directions.
Authors: Jaiswal, Sheetal1 (AUTHOR), Yadav, Paramjeet1 (AUTHOR), Kumar, Rajesh1 (AUTHOR) orajesh@bhu.ac.in
Source: Polymers for Advanced Technologies. Dec2024, Vol. 35 Issue 12, p1-26. 26p.
Subjects: Aerogels, Porosity, Tissue engineering, Regenerative medicine, Medical research
Abstract: Aerogels are garnering considerable attention in biomedical fields due to their unique physicochemical properties. These materials are noted for their low density, high porosity, and customizable pore structures, making them highly suitable for applications such as drug delivery, regenerative medicine, and wound healing. They provide excellent platforms for loading drugs and active biomolecules. Consequently, research into the therapeutic potential of aerogels has surged, both in vitro and in vivo, reflecting an increased acknowledgment of their biomedical promise. Despite this growing body of research, detailed data on the in vivo performance and safety of aerogels remain sparse. While polymer‐based, silica‐based, and hybrid aerogels are generally deemed safe, there is still a lack of comprehensive understanding regarding their acute, subacute, and chronic toxicity. This review presents a thorough examination of the biomedical applications of aerogels, exploring both conventional uses and innovative applications like decontamination. We assess the biological impacts of aerogels on cells and organisms, focusing on their therapeutic effectiveness and safety. Through this detailed review, we aim to highlight the current state of aerogel research in the biomedical field and pinpoint key areas where further investigation is needed to ensure their safe and effective use in medical applications. [ABSTRACT FROM AUTHOR]
Copyright of Polymers for Advanced Technologies is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Biomedical Applications of Aerogels: Therapeutic Potential, Safety, and Future Research Directions.
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  Data: <searchLink fieldCode="AR" term="%22Jaiswal%2C+Sheetal%22">Jaiswal, Sheetal</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yadav%2C+Paramjeet%22">Yadav, Paramjeet</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kumar%2C+Rajesh%22">Kumar, Rajesh</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> orajesh@bhu.ac.in</i>
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  Data: <searchLink fieldCode="JN" term="%22Polymers+for+Advanced+Technologies%22">Polymers for Advanced Technologies</searchLink>. Dec2024, Vol. 35 Issue 12, p1-26. 26p.
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  Data: <searchLink fieldCode="DE" term="%22Aerogels%22">Aerogels</searchLink><br /><searchLink fieldCode="DE" term="%22Porosity%22">Porosity</searchLink><br /><searchLink fieldCode="DE" term="%22Tissue+engineering%22">Tissue engineering</searchLink><br /><searchLink fieldCode="DE" term="%22Regenerative+medicine%22">Regenerative medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+research%22">Medical research</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Aerogels are garnering considerable attention in biomedical fields due to their unique physicochemical properties. These materials are noted for their low density, high porosity, and customizable pore structures, making them highly suitable for applications such as drug delivery, regenerative medicine, and wound healing. They provide excellent platforms for loading drugs and active biomolecules. Consequently, research into the therapeutic potential of aerogels has surged, both in vitro and in vivo, reflecting an increased acknowledgment of their biomedical promise. Despite this growing body of research, detailed data on the in vivo performance and safety of aerogels remain sparse. While polymer‐based, silica‐based, and hybrid aerogels are generally deemed safe, there is still a lack of comprehensive understanding regarding their acute, subacute, and chronic toxicity. This review presents a thorough examination of the biomedical applications of aerogels, exploring both conventional uses and innovative applications like decontamination. We assess the biological impacts of aerogels on cells and organisms, focusing on their therapeutic effectiveness and safety. Through this detailed review, we aim to highlight the current state of aerogel research in the biomedical field and pinpoint key areas where further investigation is needed to ensure their safe and effective use in medical applications. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Polymers for Advanced Technologies is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1002/pat.70019
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      – Code: eng
        Text: English
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        PageCount: 26
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      – SubjectFull: Aerogels
        Type: general
      – SubjectFull: Porosity
        Type: general
      – SubjectFull: Tissue engineering
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      – SubjectFull: Regenerative medicine
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      – SubjectFull: Medical research
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      – TitleFull: Biomedical Applications of Aerogels: Therapeutic Potential, Safety, and Future Research Directions.
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            – D: 01
              M: 12
              Text: Dec2024
              Type: published
              Y: 2024
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