Coral incorporating microplastics leads to a health-risking immunometabolic shift.
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| Title: | Coral incorporating microplastics leads to a health-risking immunometabolic shift. |
|---|---|
| Authors: | Tang, Chuan-Ho1,2,3 (AUTHOR) chtang@nmmba.gov.tw, Lin, Ching-Yu4 (AUTHOR), Li, Hsing-Hui1,2 (AUTHOR) |
| Source: | Chemosphere. Apr2025, Vol. 374, pN.PAG-N.PAG. 1p. |
| Subjects: | Coral diseases, Ether lipids, Marine pollution, Disease susceptibility, Cell death |
| Abstract: | Microplastic pollution has been associated with coral susceptibility to disease, yet the underlying mechanism is unclear. An untargeted lipidomic profiling was therefore performed to gain an insight into the effect of microplastics on a vulnerable coral (Turbinaria mesenterina) of actively reacting to suspended particles. Expending storage lipids on actions such as increasing 20:4-possessing ether membrane lipids and mitochondrial β-oxidation for immunoactivation was observed in coral hosts. A molecular realignment of symbiotic communication was correspondingly observed from symbiotic algae activating anti-inflammatory actions, which employed the 22:6-deriving effects that expended storage lipids as well, by, for example, increasing 22:6-possessing membrane lipids. Symbiotic algae reacting against the heightened host immunity also led to a metabolic compromise that lowered photoprotective capacity. Worryingly, increasing these polyunsaturated membrane lipids potentially sensitize the cells to oxidative stress-induced cell death that was simultaneously indicated by a sphingolipid profile as lipid peroxidation preliminarily increased in coral. Microplastic accumulation thus potentially increase coral susceptibility to environmental factors being able to elevating the oxidative stress, such as light-heat stress. In this manner, microplastic pollution in the ocean would chronically impair coral health, being highlighted by this study. [Display omitted] • Coral incorporating microplastics induces an inflammatory response. • Lipid immunometabolism is activated in coral host cells. • Algal symbionts realign molecular communication against the host hyper-immunity. • Incorporated microplastics would sensitize coral to environmental insults. [ABSTRACT FROM AUTHOR] |
| Copyright of Chemosphere is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 183277006 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Coral incorporating microplastics leads to a health-risking immunometabolic shift. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Tang%2C+Chuan-Ho%22">Tang, Chuan-Ho</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<i> chtang@nmmba.gov.tw</i><br /><searchLink fieldCode="AR" term="%22Lin%2C+Ching-Yu%22">Lin, Ching-Yu</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Li%2C+Hsing-Hui%22">Li, Hsing-Hui</searchLink><relatesTo>1,2</relatesTo> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Chemosphere%22">Chemosphere</searchLink>. Apr2025, Vol. 374, pN.PAG-N.PAG. 1p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Coral+diseases%22">Coral diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Ether+lipids%22">Ether lipids</searchLink><br /><searchLink fieldCode="DE" term="%22Marine+pollution%22">Marine pollution</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+susceptibility%22">Disease susceptibility</searchLink><br /><searchLink fieldCode="DE" term="%22Cell+death%22">Cell death</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Microplastic pollution has been associated with coral susceptibility to disease, yet the underlying mechanism is unclear. An untargeted lipidomic profiling was therefore performed to gain an insight into the effect of microplastics on a vulnerable coral (Turbinaria mesenterina) of actively reacting to suspended particles. Expending storage lipids on actions such as increasing 20:4-possessing ether membrane lipids and mitochondrial β-oxidation for immunoactivation was observed in coral hosts. A molecular realignment of symbiotic communication was correspondingly observed from symbiotic algae activating anti-inflammatory actions, which employed the 22:6-deriving effects that expended storage lipids as well, by, for example, increasing 22:6-possessing membrane lipids. Symbiotic algae reacting against the heightened host immunity also led to a metabolic compromise that lowered photoprotective capacity. Worryingly, increasing these polyunsaturated membrane lipids potentially sensitize the cells to oxidative stress-induced cell death that was simultaneously indicated by a sphingolipid profile as lipid peroxidation preliminarily increased in coral. Microplastic accumulation thus potentially increase coral susceptibility to environmental factors being able to elevating the oxidative stress, such as light-heat stress. In this manner, microplastic pollution in the ocean would chronically impair coral health, being highlighted by this study. [Display omitted] • Coral incorporating microplastics induces an inflammatory response. • Lipid immunometabolism is activated in coral host cells. • Algal symbionts realign molecular communication against the host hyper-immunity. • Incorporated microplastics would sensitize coral to environmental insults. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Chemosphere is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.chemosphere.2025.144245 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 1 StartPage: N.PAG Subjects: – SubjectFull: Coral diseases Type: general – SubjectFull: Ether lipids Type: general – SubjectFull: Marine pollution Type: general – SubjectFull: Disease susceptibility Type: general – SubjectFull: Cell death Type: general Titles: – TitleFull: Coral incorporating microplastics leads to a health-risking immunometabolic shift. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tang, Chuan-Ho – PersonEntity: Name: NameFull: Lin, Ching-Yu – PersonEntity: Name: NameFull: Li, Hsing-Hui IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: Apr2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 00456535 Numbering: – Type: volume Value: 374 Titles: – TitleFull: Chemosphere Type: main |
| ResultId | 1 |
