Interpenetrating Polymer Networks in Biomedical Fields: Recent Advanced and Applications.

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Title: Interpenetrating Polymer Networks in Biomedical Fields: Recent Advanced and Applications.
Authors: Shahi, Farangis1 (AUTHOR), Zarei, Sara2 (AUTHOR), Salah Othman, Razhan3,4 (AUTHOR), Afshar, Hana5 (AUTHOR), Kamran, Farimah6 (AUTHOR), Afshar Taromi, Arsia7 (AUTHOR) arsia.afshar@ippi.ac.ir, Khonakdar, Hossein Ali2 (AUTHOR) hakhonakdar@gmail.com
Source: Polymers for Advanced Technologies. Feb2025, Vol. 36 Issue 2, p1-33. 33p.
Subjects: Cell adhesion, Medical polymers, Hydrogels, Research personnel, Polymer networks
Abstract: Recent developments in polymer materials have led to an increased implementation of hydrogels in biomedical settings, especially in the creation of smart hydrogels. Traditional single‐network hydrogels often exhibit challenges, such as poor mechanical strength, insufficient biocompatibility, and slow response rates. To address these issues, researchers have introduced Interpenetrating Polymer Network (IPN) hydrogels, which significantly improve mechanical strength via topological entanglements and physical interactions. This dual‐network design not only enhances biocompatibility but also responsiveness to stimuli, endowing the hydrogels with distinctive properties like cell adhesion, conductivity, hemostatic functions, antioxidant abilities, and color‐changing properties. The purpose of this article is to elucidate the factors that trigger stimuli responsiveness in IPN hydrogels, their impacts on cellular behavior, and the various biomedical applications they can serve. A comprehensive overview is provided regarding their classification, mechanisms, performance attributes, and related subjects. Ultimately, this review emphasizes the promise that smart IPN hydrogels hold in fulfilling the increasing need for innovative materials with improved mechanical features and biocompatibility in the biomedical sector. [ABSTRACT FROM AUTHOR]
Copyright of Polymers for Advanced Technologies is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Interpenetrating Polymer Networks in Biomedical Fields: Recent Advanced and Applications.
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  Data: <searchLink fieldCode="AR" term="%22Shahi%2C+Farangis%22">Shahi, Farangis</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zarei%2C+Sara%22">Zarei, Sara</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Salah+Othman%2C+Razhan%22">Salah Othman, Razhan</searchLink><relatesTo>3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Afshar%2C+Hana%22">Afshar, Hana</searchLink><relatesTo>5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kamran%2C+Farimah%22">Kamran, Farimah</searchLink><relatesTo>6</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Afshar+Taromi%2C+Arsia%22">Afshar Taromi, Arsia</searchLink><relatesTo>7</relatesTo> (AUTHOR)<i> arsia.afshar@ippi.ac.ir</i><br /><searchLink fieldCode="AR" term="%22Khonakdar%2C+Hossein+Ali%22">Khonakdar, Hossein Ali</searchLink><relatesTo>2</relatesTo> (AUTHOR)<i> hakhonakdar@gmail.com</i>
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  Data: <searchLink fieldCode="JN" term="%22Polymers+for+Advanced+Technologies%22">Polymers for Advanced Technologies</searchLink>. Feb2025, Vol. 36 Issue 2, p1-33. 33p.
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  Data: <searchLink fieldCode="DE" term="%22Cell+adhesion%22">Cell adhesion</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+polymers%22">Medical polymers</searchLink><br /><searchLink fieldCode="DE" term="%22Hydrogels%22">Hydrogels</searchLink><br /><searchLink fieldCode="DE" term="%22Research+personnel%22">Research personnel</searchLink><br /><searchLink fieldCode="DE" term="%22Polymer+networks%22">Polymer networks</searchLink>
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  Data: Recent developments in polymer materials have led to an increased implementation of hydrogels in biomedical settings, especially in the creation of smart hydrogels. Traditional single‐network hydrogels often exhibit challenges, such as poor mechanical strength, insufficient biocompatibility, and slow response rates. To address these issues, researchers have introduced Interpenetrating Polymer Network (IPN) hydrogels, which significantly improve mechanical strength via topological entanglements and physical interactions. This dual‐network design not only enhances biocompatibility but also responsiveness to stimuli, endowing the hydrogels with distinctive properties like cell adhesion, conductivity, hemostatic functions, antioxidant abilities, and color‐changing properties. The purpose of this article is to elucidate the factors that trigger stimuli responsiveness in IPN hydrogels, their impacts on cellular behavior, and the various biomedical applications they can serve. A comprehensive overview is provided regarding their classification, mechanisms, performance attributes, and related subjects. Ultimately, this review emphasizes the promise that smart IPN hydrogels hold in fulfilling the increasing need for innovative materials with improved mechanical features and biocompatibility in the biomedical sector. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of Polymers for Advanced Technologies is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1002/pat.70099
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        Text: English
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        PageCount: 33
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    Subjects:
      – SubjectFull: Cell adhesion
        Type: general
      – SubjectFull: Medical polymers
        Type: general
      – SubjectFull: Hydrogels
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      – SubjectFull: Research personnel
        Type: general
      – SubjectFull: Polymer networks
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      – TitleFull: Interpenetrating Polymer Networks in Biomedical Fields: Recent Advanced and Applications.
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            NameFull: Shahi, Farangis
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            NameFull: Zarei, Sara
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            NameFull: Salah Othman, Razhan
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            NameFull: Afshar, Hana
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            NameFull: Kamran, Farimah
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            NameFull: Afshar Taromi, Arsia
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            NameFull: Khonakdar, Hossein Ali
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              M: 02
              Text: Feb2025
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              Y: 2025
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