ESTUDIO DE LAS ETAPAS CRÍTICAS DEL PROCESO DE PRODUCCIÓN DE UN POLIFÁRMACO/TABLETAS DE DIPIRONA CON DIAZEPAM.
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| Title: | ESTUDIO DE LAS ETAPAS CRÍTICAS DEL PROCESO DE PRODUCCIÓN DE UN POLIFÁRMACO/TABLETAS DE DIPIRONA CON DIAZEPAM. |
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| Authors: | Vigo, Marlén Vistel1, Rubio, Arlobia Bosch1, Diegues, Isabel Falcón1 |
| Source: | Tecnología Química. 1999, Vol. 19 Issue 2, p60-65. 6p. |
| Subjects: | Total quality control, Quality control, Drugs, Manufacturing processes, Pharmaceutical industry |
| Abstract (English): | The need to increase our production quality, including polymedicaments non collected in Pharmacopeias, in the light of the total quality control, which is a premise for the performance of the circular letter from the State Center for Drug Control (CECMED), in relation to the process validation and the demonstration of the good performance of existing drugs. This led to a deepening in critical stages from the production process of such formula: the dry powder blending and the compression. The feasibility of attaining a lower range for the average mass by means of an adequate adjustment of shaping machines and the influence of stages after the dry blending in obtaining the sample homogeneity. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | La necesidad de elevar la calidad de nuestras producciones, incluyendo los polifármacos no recogidos en Farmacopeas, a la luz del control total de la calidad, lo que constituye una premisa para el cumplimiento de la circular del Centro Estatal para el Control de los Medicamentos (CECMED) en relación con la validación de los procesos y la demostración del buen desempeño de los medicamentos existentes, conllevó una profundización en las etapas críticas del proceso de producción de dicha fórmula: el mezclado seco de los polvos y la compresión. Se demuestra la factibilidad de lograr un rango menor para la masa promedio mediante un adecuado ajuste de las máquinas troqueladoras y la influencia de las etapas posteriores al mezclado seco en la obtención de una adecuada homogeneidad de la muestra. [ABSTRACT FROM AUTHOR] |
| Copyright of Tecnología Química is the property of Direccion de Informacion Cientifico-Tecnica Universidad de Oriente and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 18428587 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: ESTUDIO DE LAS ETAPAS CRÍTICAS DEL PROCESO DE PRODUCCIÓN DE UN POLIFÁRMACO/TABLETAS DE DIPIRONA CON DIAZEPAM. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Vigo%2C+Marlén+Vistel%22">Vigo, Marlén Vistel</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Rubio%2C+Arlobia+Bosch%22">Rubio, Arlobia Bosch</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Diegues%2C+Isabel+Falcón%22">Diegues, Isabel Falcón</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Tecnología+Química%22">Tecnología Química</searchLink>. 1999, Vol. 19 Issue 2, p60-65. 6p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Total+quality+control%22">Total quality control</searchLink><br /><searchLink fieldCode="DE" term="%22Quality+control%22">Quality control</searchLink><br /><searchLink fieldCode="DE" term="%22Drugs%22">Drugs</searchLink><br /><searchLink fieldCode="DE" term="%22Manufacturing+processes%22">Manufacturing processes</searchLink><br /><searchLink fieldCode="DE" term="%22Pharmaceutical+industry%22">Pharmaceutical industry</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: The need to increase our production quality, including polymedicaments non collected in Pharmacopeias, in the light of the total quality control, which is a premise for the performance of the circular letter from the State Center for Drug Control (CECMED), in relation to the process validation and the demonstration of the good performance of existing drugs. This led to a deepening in critical stages from the production process of such formula: the dry powder blending and the compression. The feasibility of attaining a lower range for the average mass by means of an adequate adjustment of shaping machines and the influence of stages after the dry blending in obtaining the sample homogeneity. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: La necesidad de elevar la calidad de nuestras producciones, incluyendo los polifármacos no recogidos en Farmacopeas, a la luz del control total de la calidad, lo que constituye una premisa para el cumplimiento de la circular del Centro Estatal para el Control de los Medicamentos (CECMED) en relación con la validación de los procesos y la demostración del buen desempeño de los medicamentos existentes, conllevó una profundización en las etapas críticas del proceso de producción de dicha fórmula: el mezclado seco de los polvos y la compresión. Se demuestra la factibilidad de lograr un rango menor para la masa promedio mediante un adecuado ajuste de las máquinas troqueladoras y la influencia de las etapas posteriores al mezclado seco en la obtención de una adecuada homogeneidad de la muestra. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Tecnología Química is the property of Direccion de Informacion Cientifico-Tecnica Universidad de Oriente and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 6 StartPage: 60 Subjects: – SubjectFull: Total quality control Type: general – SubjectFull: Quality control Type: general – SubjectFull: Drugs Type: general – SubjectFull: Manufacturing processes Type: general – SubjectFull: Pharmaceutical industry Type: general Titles: – TitleFull: ESTUDIO DE LAS ETAPAS CRÍTICAS DEL PROCESO DE PRODUCCIÓN DE UN POLIFÁRMACO/TABLETAS DE DIPIRONA CON DIAZEPAM. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Vigo, Marlén Vistel – PersonEntity: Name: NameFull: Rubio, Arlobia Bosch – PersonEntity: Name: NameFull: Diegues, Isabel Falcón IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: 1999 Type: published Y: 1999 Identifiers: – Type: issn-print Value: 00418420 Numbering: – Type: volume Value: 19 – Type: issue Value: 2 Titles: – TitleFull: Tecnología Química Type: main |
| ResultId | 1 |
