Changes in the metabolite profile and bacterial neuraminidase inhibitory activity in adzuki bean (Vigna angularis) seedlings during harvest, as revealed by an LC-MS based metabolomic approach.
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| Title: | Changes in the metabolite profile and bacterial neuraminidase inhibitory activity in adzuki bean (Vigna angularis) seedlings during harvest, as revealed by an LC-MS based metabolomic approach. |
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| Authors: | Lee, Han Gyeol1 (AUTHOR) gajae54@korea.kr, Son, So-Ri1,2 (AUTHOR) allosori@khu.ac.kr, Lee, So Young3 (AUTHOR) thdudrhswl@khu.ac.kr, Ju, Young Kwang4 (AUTHOR) jyh5807@korea.kr, Seo, Hye Young1 (AUTHOR) seohy1228@korea.kr, Jang, Dae Sik1,2,3 (AUTHOR) dsjang@khu.ac.kr, Seo, Woo Duck1 (AUTHOR) swd2002@korea.kr |
| Source: | Food Chemistry. Aug2025, Vol. 483, pN.PAG-N.PAG. 1p. |
| Subjects: | Principal components analysis, Bacterial metabolites, Discriminant analysis, Numbers of species, Cultivars |
| Abstract: | Edible seedlings are known for their nutritional value and potential health benefits; however, only a limited number of species are currently utilized. To explore new resources, we performed comprehensive metabolite profiling of adzuki bean (Vigna angularis) seedlings using eight cultivars. Through LC-MS/MS fingerprint analysis combined with principal component analysis, significant metabolic changes were revealed in day 11 seedlings, leading to the identification of sixteen compounds including a new coumestan glycoside. Further LC-MS/MS analysis identified 133 metabolites, which were validated by molecular networking. Using fold change and orthogonal partial least squares discriminant analysis, we found that the metabolite changes effectively distinguished between different growth states and cultivars, with flavonoids, and saponins being predominantly observed on days 7–11. Notably, high levels of bacterial neuraminidase metabolites were detected in ARR cultivar at day 7 and in YDC cultivar during days 9–11, suggesting the potential of adzuki bean seedlings as a functional food. [Display omitted] • Sixteen compounds, including an unreported coumestan glycoside, were isolated from adzuki bean seedlings. • LC-MS/MS analysis identified 133 metabolites, as validated by molecular networking • The metabolite changes distinguished between different growth states and cultivars • High levels of bacterial neuraminidase metabolites were detected at day 7 in ARR and days 9–11 in YDC cultivar [ABSTRACT FROM AUTHOR] |
| Copyright of Food Chemistry is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 184912003 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Changes in the metabolite profile and bacterial neuraminidase inhibitory activity in adzuki bean (Vigna angularis) seedlings during harvest, as revealed by an LC-MS based metabolomic approach. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Lee%2C+Han+Gyeol%22">Lee, Han Gyeol</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> gajae54@korea.kr</i><br /><searchLink fieldCode="AR" term="%22Son%2C+So-Ri%22">Son, So-Ri</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> allosori@khu.ac.kr</i><br /><searchLink fieldCode="AR" term="%22Lee%2C+So+Young%22">Lee, So Young</searchLink><relatesTo>3</relatesTo> (AUTHOR)<i> thdudrhswl@khu.ac.kr</i><br /><searchLink fieldCode="AR" term="%22Ju%2C+Young+Kwang%22">Ju, Young Kwang</searchLink><relatesTo>4</relatesTo> (AUTHOR)<i> jyh5807@korea.kr</i><br /><searchLink fieldCode="AR" term="%22Seo%2C+Hye+Young%22">Seo, Hye Young</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> seohy1228@korea.kr</i><br /><searchLink fieldCode="AR" term="%22Jang%2C+Dae+Sik%22">Jang, Dae Sik</searchLink><relatesTo>1,2,3</relatesTo> (AUTHOR)<i> dsjang@khu.ac.kr</i><br /><searchLink fieldCode="AR" term="%22Seo%2C+Woo+Duck%22">Seo, Woo Duck</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> swd2002@korea.kr</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Food+Chemistry%22">Food Chemistry</searchLink>. Aug2025, Vol. 483, pN.PAG-N.PAG. 1p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Principal+components+analysis%22">Principal components analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Bacterial+metabolites%22">Bacterial metabolites</searchLink><br /><searchLink fieldCode="DE" term="%22Discriminant+analysis%22">Discriminant analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Numbers+of+species%22">Numbers of species</searchLink><br /><searchLink fieldCode="DE" term="%22Cultivars%22">Cultivars</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Edible seedlings are known for their nutritional value and potential health benefits; however, only a limited number of species are currently utilized. To explore new resources, we performed comprehensive metabolite profiling of adzuki bean (Vigna angularis) seedlings using eight cultivars. Through LC-MS/MS fingerprint analysis combined with principal component analysis, significant metabolic changes were revealed in day 11 seedlings, leading to the identification of sixteen compounds including a new coumestan glycoside. Further LC-MS/MS analysis identified 133 metabolites, which were validated by molecular networking. Using fold change and orthogonal partial least squares discriminant analysis, we found that the metabolite changes effectively distinguished between different growth states and cultivars, with flavonoids, and saponins being predominantly observed on days 7–11. Notably, high levels of bacterial neuraminidase metabolites were detected in ARR cultivar at day 7 and in YDC cultivar during days 9–11, suggesting the potential of adzuki bean seedlings as a functional food. [Display omitted] • Sixteen compounds, including an unreported coumestan glycoside, were isolated from adzuki bean seedlings. • LC-MS/MS analysis identified 133 metabolites, as validated by molecular networking • The metabolite changes distinguished between different growth states and cultivars • High levels of bacterial neuraminidase metabolites were detected at day 7 in ARR and days 9–11 in YDC cultivar [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Food Chemistry is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.foodchem.2025.144060 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 1 StartPage: N.PAG Subjects: – SubjectFull: Principal components analysis Type: general – SubjectFull: Bacterial metabolites Type: general – SubjectFull: Discriminant analysis Type: general – SubjectFull: Numbers of species Type: general – SubjectFull: Cultivars Type: general Titles: – TitleFull: Changes in the metabolite profile and bacterial neuraminidase inhibitory activity in adzuki bean (Vigna angularis) seedlings during harvest, as revealed by an LC-MS based metabolomic approach. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lee, Han Gyeol – PersonEntity: Name: NameFull: Son, So-Ri – PersonEntity: Name: NameFull: Lee, So Young – PersonEntity: Name: NameFull: Ju, Young Kwang – PersonEntity: Name: NameFull: Seo, Hye Young – PersonEntity: Name: NameFull: Jang, Dae Sik – PersonEntity: Name: NameFull: Seo, Woo Duck IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 08 Text: Aug2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 03088146 Numbering: – Type: volume Value: 483 Titles: – TitleFull: Food Chemistry Type: main |
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