Changes in the metabolite profile and bacterial neuraminidase inhibitory activity in adzuki bean (Vigna angularis) seedlings during harvest, as revealed by an LC-MS based metabolomic approach.
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| Title: | Changes in the metabolite profile and bacterial neuraminidase inhibitory activity in adzuki bean (Vigna angularis) seedlings during harvest, as revealed by an LC-MS based metabolomic approach. |
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| Authors: | Lee, Han Gyeol1 (AUTHOR) gajae54@korea.kr, Son, So-Ri1,2 (AUTHOR) allosori@khu.ac.kr, Lee, So Young3 (AUTHOR) thdudrhswl@khu.ac.kr, Ju, Young Kwang4 (AUTHOR) jyh5807@korea.kr, Seo, Hye Young1 (AUTHOR) seohy1228@korea.kr, Jang, Dae Sik1,2,3 (AUTHOR) dsjang@khu.ac.kr, Seo, Woo Duck1 (AUTHOR) swd2002@korea.kr |
| Source: | Food Chemistry. Aug2025, Vol. 483, pN.PAG-N.PAG. 1p. |
| Subjects: | Principal components analysis, Bacterial metabolites, Discriminant analysis, Numbers of species, Cultivars |
| Abstract: | Edible seedlings are known for their nutritional value and potential health benefits; however, only a limited number of species are currently utilized. To explore new resources, we performed comprehensive metabolite profiling of adzuki bean (Vigna angularis) seedlings using eight cultivars. Through LC-MS/MS fingerprint analysis combined with principal component analysis, significant metabolic changes were revealed in day 11 seedlings, leading to the identification of sixteen compounds including a new coumestan glycoside. Further LC-MS/MS analysis identified 133 metabolites, which were validated by molecular networking. Using fold change and orthogonal partial least squares discriminant analysis, we found that the metabolite changes effectively distinguished between different growth states and cultivars, with flavonoids, and saponins being predominantly observed on days 7–11. Notably, high levels of bacterial neuraminidase metabolites were detected in ARR cultivar at day 7 and in YDC cultivar during days 9–11, suggesting the potential of adzuki bean seedlings as a functional food. [Display omitted] • Sixteen compounds, including an unreported coumestan glycoside, were isolated from adzuki bean seedlings. • LC-MS/MS analysis identified 133 metabolites, as validated by molecular networking • The metabolite changes distinguished between different growth states and cultivars • High levels of bacterial neuraminidase metabolites were detected at day 7 in ARR and days 9–11 in YDC cultivar [ABSTRACT FROM AUTHOR] |
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| Database: | Engineering Source |
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