View in EDS HTML Full Text PDF Full Text

Assessment of four-dimensional flow MRI for prediction of varices risk in cirrhotic patients.

Saved in:
Bibliographic Details
Title: Assessment of four-dimensional flow MRI for prediction of varices risk in cirrhotic patients.
Authors: Hu, Qinqin1 (AUTHOR), Li, Gangjing1 (AUTHOR), Zhang, Dechuan1 (AUTHOR), Jiang, Yang1 (AUTHOR), Nie, Lisha2 (AUTHOR), Yang, Huiping1 (AUTHOR) 8661054@qq.com, Yang, Hua1 (AUTHOR) 13527547568@163.com
Source: European Radiology. Jun2025, Vol. 35 Issue 6, p3568-3575. 8p.
Subjects: Cirrhosis of the liver, Varicose veins, Portal vein, Splenic artery, Computer-assisted image analysis (Medicine), Hemodynamic monitoring, Clinical medicine
Abstract: Objective: This study aims to validate the application of abdominal four-dimensional flow magnetic resonance imaging (MRI) for cirrhotic patients and quantify its effectiveness in assessing the hemodynamic impacts of cirrhosis to evaluate varices. Methods: All consecutive patients who underwent MRIs between September 2022 and June 2023 were enrolled. Groups were divided into varicose, non-varicose, and healthy groups. ANOVA and post hoc LSD-t tests were used for statistical analysis. The correlation between hemodynamic parameters and liver function grade was evaluated using Kendall's correlation coefficient. Results: A total of 80 patients were included (53 cirrhotic, 27 healthy). Significant disparities were found in main portal vein flow (MPV-FR), splenic vein flow (SV-FR), and vessel diameters (MPV-VD, SV-VD) among the groups (p < 0.05). MPV-FR was higher in the varicose group (24.81 ± 8.52) compared to non-varicose (19.52 ± 5.07) and healthy groups (17.26 ± 5.48). The most robust assessment of variceal risk was achieved by combining the flow rates (FRs) and VDs of MPV and SV (AUC 0.83, 95% CI 0.72–0.94). Conclusion: The combined indices of FRs and VDs of MPV and SV effectively predict the occurrence of varicose veins in cirrhotic patients. Key Points: QuestionNon-invasive prediction of variceal risk is essential for the clinical management of advanced chronic cirrhosis, yet existing clinical examinations are inadequate. FindingsThe effective assessment of variceal risk was achieved by combining the flow rates and vessel diameters of the main portal vein and splenic vein. Clinical relevanceFour-dimensional flow MRI can reveal hemodynamic changes in cirrhotic patients and assist in identifying gastroesophageal varices, serving as a marker for varices risk prediction. [ABSTRACT FROM AUTHOR]
Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: egs
DbLabel: Engineering Source
An: 185184273
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Assessment of four-dimensional flow MRI for prediction of varices risk in cirrhotic patients.
– Name: Author
  Label: Authors
  Group: Au
  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Hu%2C+Qinqin%22&quot;&gt;Hu, Qinqin&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Li%2C+Gangjing%22&quot;&gt;Li, Gangjing&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Zhang%2C+Dechuan%22&quot;&gt;Zhang, Dechuan&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Jiang%2C+Yang%22&quot;&gt;Jiang, Yang&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Nie%2C+Lisha%22&quot;&gt;Nie, Lisha&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Yang%2C+Huiping%22&quot;&gt;Yang, Huiping&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt; (AUTHOR)&lt;i&gt; 8661054@qq.com&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Yang%2C+Hua%22&quot;&gt;Yang, Hua&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt; (AUTHOR)&lt;i&gt; 13527547568@163.com&lt;/i&gt;
– Name: TitleSource
  Label: Source
  Group: Src
  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22European+Radiology%22&quot;&gt;European Radiology&lt;/searchLink&gt;. Jun2025, Vol. 35 Issue 6, p3568-3575. 8p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Cirrhosis+of+the+liver%22&quot;&gt;Cirrhosis of the liver&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Varicose+veins%22&quot;&gt;Varicose veins&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Portal+vein%22&quot;&gt;Portal vein&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Splenic+artery%22&quot;&gt;Splenic artery&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Computer-assisted+image+analysis+%28Medicine%29%22&quot;&gt;Computer-assisted image analysis (Medicine)&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Hemodynamic+monitoring%22&quot;&gt;Hemodynamic monitoring&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Clinical+medicine%22&quot;&gt;Clinical medicine&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objective: This study aims to validate the application of abdominal four-dimensional flow magnetic resonance imaging (MRI) for cirrhotic patients and quantify its effectiveness in assessing the hemodynamic impacts of cirrhosis to evaluate varices. Methods: All consecutive patients who underwent MRIs between September 2022 and June 2023 were enrolled. Groups were divided into varicose, non-varicose, and healthy groups. ANOVA and post hoc LSD-t tests were used for statistical analysis. The correlation between hemodynamic parameters and liver function grade was evaluated using Kendall&#39;s correlation coefficient. Results: A total of 80 patients were included (53 cirrhotic, 27 healthy). Significant disparities were found in main portal vein flow (MPV-FR), splenic vein flow (SV-FR), and vessel diameters (MPV-VD, SV-VD) among the groups (p &lt; 0.05). MPV-FR was higher in the varicose group (24.81 &#177; 8.52) compared to non-varicose (19.52 &#177; 5.07) and healthy groups (17.26 &#177; 5.48). The most robust assessment of variceal risk was achieved by combining the flow rates (FRs) and VDs of MPV and SV (AUC 0.83, 95% CI 0.72–0.94). Conclusion: The combined indices of FRs and VDs of MPV and SV effectively predict the occurrence of varicose veins in cirrhotic patients. Key Points: QuestionNon-invasive prediction of variceal risk is essential for the clinical management of advanced chronic cirrhosis, yet existing clinical examinations are inadequate. FindingsThe effective assessment of variceal risk was achieved by combining the flow rates and vessel diameters of the main portal vein and splenic vein. Clinical relevanceFour-dimensional flow MRI can reveal hemodynamic changes in cirrhotic patients and assist in identifying gastroesophageal varices, serving as a marker for varices risk prediction. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: &lt;i&gt;Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=185184273
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s00330-024-11222-4
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 3568
    Subjects:
      – SubjectFull: Cirrhosis of the liver
        Type: general
      – SubjectFull: Varicose veins
        Type: general
      – SubjectFull: Portal vein
        Type: general
      – SubjectFull: Splenic artery
        Type: general
      – SubjectFull: Computer-assisted image analysis (Medicine)
        Type: general
      – SubjectFull: Hemodynamic monitoring
        Type: general
      – SubjectFull: Clinical medicine
        Type: general
    Titles:
      – TitleFull: Assessment of four-dimensional flow MRI for prediction of varices risk in cirrhotic patients.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Hu, Qinqin
      – PersonEntity:
          Name:
            NameFull: Li, Gangjing
      – PersonEntity:
          Name:
            NameFull: Zhang, Dechuan
      – PersonEntity:
          Name:
            NameFull: Jiang, Yang
      – PersonEntity:
          Name:
            NameFull: Nie, Lisha
      – PersonEntity:
          Name:
            NameFull: Yang, Huiping
      – PersonEntity:
          Name:
            NameFull: Yang, Hua
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 06
              Text: Jun2025
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 09387994
          Numbering:
            – Type: volume
              Value: 35
            – Type: issue
              Value: 6
          Titles:
            – TitleFull: European Radiology
              Type: main
ResultId 1