Transforming medical diagnostics with metasurface terahertz biosensing technology: a label-free biosensor for detecting multiple diseases.
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| Title: | Transforming medical diagnostics with metasurface terahertz biosensing technology: a label-free biosensor for detecting multiple diseases. |
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| Authors: | Sheheryar, Taha1 (AUTHOR), Tian, Ye2 (AUTHOR), Lv, Bo1 (AUTHOR) lb19840313@126.com, Gao, Lei3 (AUTHOR) gaolei_yida@126.com |
| Source: | Optical & Quantum Electronics. May2025, Vol. 57 Issue 5, p1-20. 20p. |
| Subjects: | Spectral sensitivity, Aluminum construction, Terahertz technology, Quality factor, Refractive index |
| Abstract: | This study presents an innovative metasurface-based terahertz biosensor that enables label-free, non-invasive and cost-effective detection of a wide array of diseases including malaria and eight types of cancers. The sensor uses a triple-resonance response to detect spectral shifts caused by refractive index variations in diseased tissues and offers exceptional disease diagnostic performance. It's simple yet innovative layered structure composed of Aluminum (Al) and Polyimide eliminates the need for complex fabrication processes and use of expensive or 2 dimensional materials which makes it a highly scalable and affordable solution in the field of advanced disease detection. With sensitivities up to 1.43 THz/RIU, a Figure of Merit of 17.54 RIU⁻¹ and a Quality Factor of 18.33, the biosensor is capable of detecting even the smallest changes in dielectric properties enabling early-stage diagnosis of infectious diseases like malaria and brain cancer. Completely polarization insensitive with wide angular stability of up to 70°, the sensor ensures reliable performance across a wide range of diverse diagnostic environments. This handy platform not only eliminates the reliance on disease-specific devices but also streamlines diagnostics which makes it ideal for resource-constrained healthcare settings. Its ease of fabrication, adaptability and ability to deliver precise, real-time and rapid results positions itself as a game-changer in personalized medicine, point-of-care diagnostics and global health initiatives while setting new standards for disease detection and management. [ABSTRACT FROM AUTHOR] |
| Copyright of Optical & Quantum Electronics is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Header | DbId: egs DbLabel: Engineering Source An: 185447737 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Transforming medical diagnostics with metasurface terahertz biosensing technology: a label-free biosensor for detecting multiple diseases. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Sheheryar%2C+Taha%22">Sheheryar, Taha</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tian%2C+Ye%22">Tian, Ye</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lv%2C+Bo%22">Lv, Bo</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> lb19840313@126.com</i><br /><searchLink fieldCode="AR" term="%22Gao%2C+Lei%22">Gao, Lei</searchLink><relatesTo>3</relatesTo> (AUTHOR)<i> gaolei_yida@126.com</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Optical+%26+Quantum+Electronics%22">Optical & Quantum Electronics</searchLink>. May2025, Vol. 57 Issue 5, p1-20. 20p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Spectral+sensitivity%22">Spectral sensitivity</searchLink><br /><searchLink fieldCode="DE" term="%22Aluminum+construction%22">Aluminum construction</searchLink><br /><searchLink fieldCode="DE" term="%22Terahertz+technology%22">Terahertz technology</searchLink><br /><searchLink fieldCode="DE" term="%22Quality+factor%22">Quality factor</searchLink><br /><searchLink fieldCode="DE" term="%22Refractive+index%22">Refractive index</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: This study presents an innovative metasurface-based terahertz biosensor that enables label-free, non-invasive and cost-effective detection of a wide array of diseases including malaria and eight types of cancers. The sensor uses a triple-resonance response to detect spectral shifts caused by refractive index variations in diseased tissues and offers exceptional disease diagnostic performance. It's simple yet innovative layered structure composed of Aluminum (Al) and Polyimide eliminates the need for complex fabrication processes and use of expensive or 2 dimensional materials which makes it a highly scalable and affordable solution in the field of advanced disease detection. With sensitivities up to 1.43 THz/RIU, a Figure of Merit of 17.54 RIU⁻¹ and a Quality Factor of 18.33, the biosensor is capable of detecting even the smallest changes in dielectric properties enabling early-stage diagnosis of infectious diseases like malaria and brain cancer. Completely polarization insensitive with wide angular stability of up to 70°, the sensor ensures reliable performance across a wide range of diverse diagnostic environments. This handy platform not only eliminates the reliance on disease-specific devices but also streamlines diagnostics which makes it ideal for resource-constrained healthcare settings. Its ease of fabrication, adaptability and ability to deliver precise, real-time and rapid results positions itself as a game-changer in personalized medicine, point-of-care diagnostics and global health initiatives while setting new standards for disease detection and management. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Optical & Quantum Electronics is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s11082-025-08225-w Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 20 StartPage: 1 Subjects: – SubjectFull: Spectral sensitivity Type: general – SubjectFull: Aluminum construction Type: general – SubjectFull: Terahertz technology Type: general – SubjectFull: Quality factor Type: general – SubjectFull: Refractive index Type: general Titles: – TitleFull: Transforming medical diagnostics with metasurface terahertz biosensing technology: a label-free biosensor for detecting multiple diseases. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sheheryar, Taha – PersonEntity: Name: NameFull: Tian, Ye – PersonEntity: Name: NameFull: Lv, Bo – PersonEntity: Name: NameFull: Gao, Lei IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: May2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 03068919 Numbering: – Type: volume Value: 57 – Type: issue Value: 5 Titles: – TitleFull: Optical & Quantum Electronics Type: main |
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