The effect of photobiomodulation on the radiosensitivity of cancer cells: a literature review.
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| Title: | The effect of photobiomodulation on the radiosensitivity of cancer cells: a literature review. |
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| Authors: | Durães, Cristina1 (AUTHOR) cristinaduraes22@gmail.com, Tabosa, Angeliny1 (AUTHOR) angel.tabosa@yahoo.com.br, Santos, Eloá1 (AUTHOR) esmangabeira@gmail.com, Jesus, Sabrina1 (AUTHOR) sabrinadejesus86@gmail.com, Guimarães, Victor Hugo1 (AUTHOR) victorhg23354@hotmail.com, Queiroz, Lorena1 (AUTHOR) lorenadosreis31@gmail.com, Farias, Lucyana1 (AUTHOR) lucyanacfarias@gmail.com, Guimarães, André1 (AUTHOR) andreluizguimaraes@gmail.com |
| Source: | Lasers in Medical Science. 4/23/2025, Vol. 40 Issue 1, p1-10. 10p. |
| Abstract: | The goal of radiotherapy (RT) in cancer treatment is to destroy tumor tissue while preserving nearby healthy tissue. However, RT often causes adverse effects that significantly impact patients’ quality of life. Tumor cells, which have high proliferation rates, are susceptible to radiation, especially during the G2 and mitosis phases of the cell cycle. Numerous studies have explored ways to enhance the Radiosensitivity of tumors to make RT more effective while minimizing harm to healthy cells. This review examines the potential use of photobiomodulation (PBM) as a radiosensitizer for cancer cells to improve the effectiveness and safety of radiotherapy. A literature search was conducted in the MEDLINE/PubMed and Google Scholar databases using keywords like “PBM, low-level light therapy, cancer cells, tumor cells, radiosensitizer, and ionizing radiation.” Studies meeting the inclusion criteria were reviewed and analyzed. Several studies investigated PBM as a radiosensitizer for various cancer cell lines, including HeLa, HeLa Kyoto, A431, SCC9, and Cal 27. Most of these studies found that pre-exposure of cancer cells to PBM improved the effectiveness of radiation in destroying tumor cells. PBM is a promising, affordable, and noninvasive technique that could improve cancer treatment outcomes by increasing tumor sensitivity to radiation and reducing side effects. However, more research is needed to thoroughly assess the benefits of combining PBM with RT. Clinical trial number: not applicable. Clinical trial number: not applicable. [ABSTRACT FROM AUTHOR] |
| Copyright of Lasers in Medical Science is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Header | DbId: egs DbLabel: Engineering Source An: 185711865 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The effect of photobiomodulation on the radiosensitivity of cancer cells: a literature review. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Durães%2C+Cristina%22">Durães, Cristina</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> cristinaduraes22@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Tabosa%2C+Angeliny%22">Tabosa, Angeliny</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> angel.tabosa@yahoo.com.br</i><br /><searchLink fieldCode="AR" term="%22Santos%2C+Eloá%22">Santos, Eloá</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> esmangabeira@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Jesus%2C+Sabrina%22">Jesus, Sabrina</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> sabrinadejesus86@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Guimarães%2C+Victor+Hugo%22">Guimarães, Victor Hugo</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> victorhg23354@hotmail.com</i><br /><searchLink fieldCode="AR" term="%22Queiroz%2C+Lorena%22">Queiroz, Lorena</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> lorenadosreis31@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Farias%2C+Lucyana%22">Farias, Lucyana</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> lucyanacfarias@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Guimarães%2C+André%22">Guimarães, André</searchLink><relatesTo>1</relatesTo> (AUTHOR)<i> andreluizguimaraes@gmail.com</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Lasers+in+Medical+Science%22">Lasers in Medical Science</searchLink>. 4/23/2025, Vol. 40 Issue 1, p1-10. 10p. – Name: Abstract Label: Abstract Group: Ab Data: The goal of radiotherapy (RT) in cancer treatment is to destroy tumor tissue while preserving nearby healthy tissue. However, RT often causes adverse effects that significantly impact patients’ quality of life. Tumor cells, which have high proliferation rates, are susceptible to radiation, especially during the G2 and mitosis phases of the cell cycle. Numerous studies have explored ways to enhance the Radiosensitivity of tumors to make RT more effective while minimizing harm to healthy cells. This review examines the potential use of photobiomodulation (PBM) as a radiosensitizer for cancer cells to improve the effectiveness and safety of radiotherapy. A literature search was conducted in the MEDLINE/PubMed and Google Scholar databases using keywords like “PBM, low-level light therapy, cancer cells, tumor cells, radiosensitizer, and ionizing radiation.” Studies meeting the inclusion criteria were reviewed and analyzed. Several studies investigated PBM as a radiosensitizer for various cancer cell lines, including HeLa, HeLa Kyoto, A431, SCC9, and Cal 27. Most of these studies found that pre-exposure of cancer cells to PBM improved the effectiveness of radiation in destroying tumor cells. PBM is a promising, affordable, and noninvasive technique that could improve cancer treatment outcomes by increasing tumor sensitivity to radiation and reducing side effects. However, more research is needed to thoroughly assess the benefits of combining PBM with RT. Clinical trial number: not applicable. Clinical trial number: not applicable. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Lasers in Medical Science is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10103-025-04465-0 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 10 StartPage: 1 Titles: – TitleFull: The effect of photobiomodulation on the radiosensitivity of cancer cells: a literature review. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Durães, Cristina – PersonEntity: Name: NameFull: Tabosa, Angeliny – PersonEntity: Name: NameFull: Santos, Eloá – PersonEntity: Name: NameFull: Jesus, Sabrina – PersonEntity: Name: NameFull: Guimarães, Victor Hugo – PersonEntity: Name: NameFull: Queiroz, Lorena – PersonEntity: Name: NameFull: Farias, Lucyana – PersonEntity: Name: NameFull: Guimarães, André IsPartOfRelationships: – BibEntity: Dates: – D: 23 M: 04 Text: 4/23/2025 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 02688921 Numbering: – Type: volume Value: 40 – Type: issue Value: 1 Titles: – TitleFull: Lasers in Medical Science Type: main |
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